INTRODUCTION

RITZA contains Rizatriptan belongs to a class of medicines called selective serotonin 5-HT1B/1D receptor agonists. It is used to treat the headache phase of the migraine attack in adults. It reduces the swelling of blood vessels surrounding in the brain. It works by the narrowing blood vessels in the brain, stopping pain signals from being sent to the brain and blocking release of certain natural substances that cause pain, nausea and other symptoms of migraine.

Always take RITZA as directed by physician. Your doctor will decide the dose and duration of therapy depending upon your age, weight and condition. Swallow the medicine with a glass of water. It is not recommended for the use in children and adolescents under 18 years. Do not take this medicine, if you have reduced the blood flow to your legs and arms due to blocked arteries (peripheral vascular disease). It should be used with caution in pregnant or breastfeeding women. Consult your doctor before taking this medicine. Tell your doctor, if you are taking or taken or might take any other medicines. The most common side effects include dizziness, sleepiness and tiredness.

USES OF RITZA

• indicated for the treatment of migraine attacks in adults

HOW RITZA WORKS

It works by the narrowing blood vessels in the brain, stopping pain signals from being sent to the brain and blocking release of certain natural substances that cause pain, nausea and other symptoms of migraine.

DIRECTIONS FOR USE

Always take RITZA exactly as prescribed by your doctor. Swallow the medicine whole with plenty of water. If you take more of this medicine than you should, talk to your doctor. Overdose of this medicine can include dizziness, drowsiness, vomiting, fainting and slow heart rate.

SIDE EFFECTS OF RITZA

HOW TO MANAGE SIDE EFFECTS

Skin itching:

Avoid bath in hot water because hot water can irritate the skin. Moisturizers can be used regular basis to soothe and hydrate the affected area.

Nausea and vomiting:

Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

Diarrhea:

Drink lot of fluid, such as water or squash, to avoid dehydration. Do not take any other medicine without consulting your doctor.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor if you are taking:

• monoamine oxidase (MAO) inhibitor includes moclobemide, phenelzine, tranylcypromine, linezolid, or pargyline
• ergotamine or dihydro-ergotamine to treat your migraine
• methergine to prevent a migraine attack

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT RITZA

Can RITZA be used in pregnant women?

No. It should be used with caution in pregnant women. Consult your doctor before taking this medicine.

Can you take RITZA every day?

Do not use more than the two doses in any 24-hour period. Do not use this medicine more than prescribed.

REFERENCES

1. Miguel JA Láinez; Rizatriptan in the treatment of migraine; [Revised on Sep 2006] [Accessed 24 Dec 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671815/

2. K.D.Tripathi, Essentials of medical pharmacology, AUTACOIDS AND RELATED DRUGS, Chapter 12 – 5-HT, ITS ANTAGONISTS AND DRUG THERAPY OF MIGRAINE, 7th edition 2013, Page – 179.

3. Glenmark Pharmaceuticals s.r.o., Electronic Medicines Compendium (EMC); [Revised on July 2016] [Accessed 24 Dec 2020] https://www.medicines.org.uk/emc/files/pil.9893.pdf

4. Merck Sharp & Dohme Limited; Electronic Medicines Compendium (EMC); [Revised on Feb 2018] [Accessed 24 Dec 2020] https://www.medicines.org.uk/emc/files/pil.7797.pdf