Rifakem 550mg Tablet 10'S

Infection Rx required

Best Price*  ₹ 319.20
MRP ₹399.00
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mfr: Alkem Laboratories Ltd * Country of Origin: India
TOTAL AMOUNT ₹ 399.00

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INTRODUCTION

RIFAKEM 550MG contains Rifaximin which belongs to the group of medicines called antibiotics. It is used to treat and prevent the recurrence of hepatic encephalopathy in adults. Hepatic encephalopathy can be defined as a decline in brain function that occurs as a result of severe liver disease like liver cirrhosis or hepatitis. It is a spectrum of neuropsychiatric abnormalities characterized by agitation, confusion, muscle problems, difficulty in speaking and in some cases coma.

RIFAKEM 550MG can also be used in the treatment of irritable bowel syndrome with diarrhea in adults. Rifaximin kills the toxic bacteria in the GI tract and which relieve the symptoms of hepatic encephalopathy and irritable bowel syndrome. This medicine can either be used alone or can be combined with medicines containing a laxative called lactulose. Taking this medicine, may cause a reddish discolouration of urine. If this symptom bothers you, contact your doctor.

The most common side effect of taking this medicine are severe diarrhea, depression and headache. If you experience severe diarrhea during or after using this medicine, contact your doctor immediately. This medicine should be used with extreme caution in patients with severe liver disease. Regular monitoring of liver function is required. Before taking this medicine, inform your doctor if you have any blockage in your intestine or if you are pregnant or breastfeeding. RIFAKEM 550MG is not recommended for use in children (aged less than 18 years). Consult your doctor before taking.

USES OF RIFAKEM 550MG

  • Treats and prevents hepatic encephalopathy in adults
  • Treats irritable bowel syndrome with diarrhea in adults

HOW RIFAKEM 550MG WORKS

Rifaximin works by inhibiting the growth of ammonia-producing bacteria in the digestive tract which are important to the pathogenesis of hepatic encephalopathy. This helps to relieve the symptoms of hepatic encephalopathy such as agitation, confusion, muscle problems and reduces its recurrence. Inhibition of toxic micro organisms in the gut wall also relieves the symptoms of irritable bowel syndrome like abdominal cramping, bloating, and diarrhea or constipation.

DIRECTIONS FOR USE

Take this medicine as directed by your physician. It can be taken with or without food. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF RIFAKEM 550MG

SERIOUS

  • oesophageal varices (bleeding from swollen blood vessels in your throat)
  • severe diarrhea

COMMON

  • depressed mood
  • headache, dizziness
  • shortness of breath
  • feeling or being sick
  • stomach pain, bloating
  • ascites (fluid accumulation in abdominal cavity)
  • skin rash or itching
  • muscle cramps
  • joint pain
  • swelling of ankles, feet or fingers

RARE

  • chest infections including pneumonia
  • cellulitis (inflammation of tissue under skin)
  • rhinitis (inflammation inside the nose)
  • dehydration (body water loss)
  • changes in blood pressure
  • constipation
  • back pain
  • feeling weak
  • bruising

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try taking this medicine with, or just after meal. Stick to simple meals. Do not eat rich or spicy food.

Bloating or wind:

Eat smaller and frequent meals. Eat and drink slowly, and exercise regularly. If the symptoms get worse, contact your doctor immediately.

Diarrhea:

Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

WARNING & PRECAUTIONS

PREGNANCY

RIFAKEM 550MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING

RIFAKEM 550MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or operate any machines if your ability is affected by this medicine.

ALCOHOL

Avoid consumption of alcohol while taking this medicine.

LIVER

RIFAKEM 550MG should be taken with caution in patients with severe liver disease. Consult your doctor for advice.

ALLERGY

Do not take this medicine if you are allergic to rifaximin or to similar types of antibiotics (such as rifampicin or rifabutin).

OTHERS

Do not take this medicine, if you:

  • have any blockage in your intestine, fever or bloody stools

INTERACTIONS

Talk to your doctor, if you are taking,

  • antibiotics (medicines used to treat infections) e.g. clarithromycin
  • warfarin (used to prevent blood clotting)
  • medicines used to treat epilepsy (e.g. phenytoin)
  • medicines to treat abnormal heartbeat (e.g. digoxin, amiodarone)
  • ciclosporin (used to suppress immune system)
  • oral contraceptives (medicines used to prevent pregnancy)

SYNOPSIS

Drug :   Rifaximin
Pharmacological Category :   Antibiotics, Rifamycin
Therapeutic Indication :  

Hepatic encephalopathy, Irritable bowel syndrome with diarrhea

Dosage Forms :   Tablet, Syrup

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT RIFAKEM 550MG

Can RIFAKEM 550MG be used in children?

No. It is not recommended for use in children (aged less than 18 years). Consult your doctor before taking.

Can RIFAKEM 550MG cause constipation?

Yes. It may rarely cause constipation in some individuals. Eat fibre rich foods like fresh fruit, vegetables and cereals and drink plenty of water.

How to take RIFAKEM 550MG?

It can be taken with or without food. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your condition.

REFERENCES

1. KD. Tripathi. Drugs for constipation and diarrhea. Essentials of Pharmacology. Seventh edition. 2013. Page – 681-682.

2. Gerald G. Briggs and Roger K. Freeman. R. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 3404-3405.

3. University of Miami. RICE Trial: Rifaximin In Chronic Hepatic Encephalopathy - A Randomized, Controlled Trial. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on September 2019] [Accessed 29th October 2020] https://www.clinicaltrials.gov/ct2/show/NCT00364689

4. Bausch Health Americas, Inc. A 6-month Efficacy, Safety, and Tolerability Study of Rifaximin In Preventing Hepatic Encephalopathy. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on September 2019] [Accessed 29th October 2020] https://www.clinicaltrials.gov/ct2/show/NCT00298038

5. Bausch Health Americas, Inc. Irritable Bowel Syndrome with Diarrhea (IBS-D) Rifaximin Re-Treatment Study (TARGET3). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on December 2017] [Accessed 29th October 2020] https://clinicaltrials.gov/ct2/show/NCT01543178

6. Steven L. Flamm. Rifaximin treatment for reduction of risk of overt hepatic encephalopathy recurrence. NCBI; PMC National National Library of Medicine, National Institute of Health. May 2011 [Accessed 29th October 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105611/

7. Kamesh Gupta, Harparam Singh Ghuman and Shivani Vijay Handa. Review of Rifaximin: Latest Treatment Frontier for Irritable Bowel Syndrome Mechanism of Action and Clinical Profile. NCBI; PMC National National Library of Medicine, National Institute of Health. August 2017 [Accessed 29th October 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582649/

8. Alfasigma S.p.A. Electronic Medicines Compendium (EMC); [Revised on July 2019] [Accessed 29th October 2020] https://www.medicines.org.uk/emc/files/pil.2976.pdf

9. Valeant Pharmaceuticals North America LLC. U.S. Food & Drug Administration; [Revised on December 2017] [Accessed 29th October 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021361s023lbl.pdf

USEFUL DIAGNOSTIC TESTS

  • Ammonia
  • Liver Function Test
  • Potassium
  • Sodium

Marketer DETAILS

    Country Of Origin
    India
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Rifakem 550mg Tablet 10'S

Rifakem 550mg Tablet 10'S Mfr: Alkem Laboratories Ltd

M.R.P.: Rs.399.00
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