Revolade 25mg Tablet 7'S

Blood Clot Rx required

Best Price*  ₹ 6,077.60
MRP ₹7,597.00
(Inclusive of all taxes) *7 Tablet(s) in a Strip * Mfr: Novartis India Ltd * Country of Origin: India
TOTAL AMOUNT ₹ 7,597.00

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INTRODUCTION

REVOLADE 25MG contains Eltrombopag which belongs to the group of medicines called thrombopoietin receptor agonists. It is used to treat low platelet count (immune thrombocytopenia) in adults and in children aged 1 year and above who are unresponsive to other medicines. Immune thrombocytopenia is a bleeding disorder characterized by decreased platelet count, unusual bleeding or bruising or bleeding in gums or nose.

It can also be used to treat thrombocytopenia in adults with hepatitis C virus infections who cannot take interferon treatment. It may also treat low blood counts caused by severe aplastic anemia in adult patients. Make sure that you do not consume any dairy foods such as cheese, butter, yoghurt or ice cream, milk or milk shakes 4 hours before or 2 hours taking this medicine. Avoid smoking while taking this medicine.

Take REVOLADE 25MG as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. During the treatment, your doctor will ask you to regularly monitor the functions of eyes, liver and blood platelets to access the improvement and to avoid side effects. The most common side effects are unusual bleeding or bruising. This medicine should be used with caution in elderly patients and in patients who are smoking or over-weight. Consult your doctor for advice. This medicine is not recommended for use in children unless prescribed by a physician.

USES OF REVOLADE 25MG

  • Treats low platelet count (immune thrombocytopenia) in adults and in children aged 1 year and above who are unresponsive to other medicines
  • Treats thrombocytopenia in adults with hepatitis C virus infections who cannot take interferon treatment
  • Treats low blood counts caused by severe aplastic anemia in adult patients

HOW REVOLADE 25MG WORKS

REVOLADE 25MG is a non-immunosuppressive Thrombopoietin (TPO) receptor agonist. It selectively targets the transmembrane surface of TPO receptor present on the surface of human bone marrow progenitor cells and megakaryocytes. It increases cells in your bone marrow and make more platelets which lowers your risk of bleeding.

DIRECTIONS FOR USE

Take REVOLADE 25MG as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose for you depending upon your condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results. Make sure that you do not consume any dairy foods such as cheese, butter, yoghurt or ice cream, milk or milk shakes 4 hours before taking this medicine or 2 hours after taking this medicine.

SIDE EFFECTS OF REVOLADE 25MG

SERIOUS

  • blood clots
  • blood in your stools.
  • yellowing of skin or whites of eyes (jaundice)
  • dark-coloured urine
  • black tarry stools
  • vomiting blood

COMMON

  • respiratory tract infection (such as common cold, cough, sore throat, pneumonia, infection of the lungs, sinuses, tonsils, nose and throat)
  • nausea, vomiting, diarrhea, loss of appetite, stomach pain, bloating
  • mouth problems (such as dry mouth, sore mouth, sensitive tongue, bleeding gums, mouth ulcers)
  • toothache
  • eye problems (dry eye, eye pain and blurred vision)
  • spinning sensation (vertigo)
  • ear pain
  • muscle pain or weakness
  • back pain or bone pain
  • heavy menstrual period
  • flu (influenza), chills
  • feeling of tingling or numbness
  • swelling, pain, redness or tenderness in one leg
  • feeling drowsy or tired
  • haematoma (localised swelling filled with blood)
  • skin rash, hair loss
  • problems with attention and memory
  • abnormal heartbeat, shortness of breath

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try taking this medicine with, or just after meal. Stick to simple meals. Do not eat rich or spicy food.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

Diarrhea:

Drink lots of fluids to avoid dehydration. Avoid taking any medicines for diarrhoea without speaking to a doctor.

WARNING & PRECAUTIONS

PREGNANCY

REVOLADE 25MG should be used with caution in pregnant women. Consult your doctor before taking this medicine.

BREASTFEEDING

REVOLADE 25MG should be used with caution in breast feeding women. Consult your doctor before taking this medicine.

DRIVING AND USING MACHINES

Do not drive or operate any machines, because this medicine may make you feel dizzy.

ALCOHOL

Avoid consumption of alcohol while taking this medicine.

LIVER

REVOLADE 25MG should be taken with caution in patients with severe liver disease. Consult your doctor for advice.

ALLERGY

Do not take this medicine if you are allergic to eltrombopag.

OTHERS

Before taking this medicine, inform your doctor if you:

  • have cancer, have recently had surgery or received a physical injury, cataracts or another blood condition, such as myelodysplastic syndrome

INTERACTIONS

Talk to your doctor, if you are taking,

  • medicines used to treat indigestion, heartburn or stomach ulcers (e.g. cimetidine)
  • medicines used to lower blood cholesterol levels (e.g. atorvastatin)
  • medicines used to treat HIV infection (e.g. lopinavir and/or ritonavir)
  • ciclosporin (used to suppress immune system)
  • vitamin and mineral supplements (containing iron, calcium, magnesium, aluminium, selenium and zinc)
  • methotrexate and topotecan (used to treat cancer)
  • corticosteroids (used to treat inflammation)
  • danazol (used to treat endometriosis)
  • azathioprine (used to treat rheumatoid arthritis)

SYNOPSIS

Drug :   Eltrombopag
Pharmacological Category :  

Thrombopoietin receptor agonist, Hematopoietic growth factor, Hemostatic agent

Therapeutic Indication :   Thrombocytopenia, Severe aplastic anemia
Dosage Forms :  

Tablet

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT REVOLADE 25MG

Can REVOLADE 25MG be taken along with milk?

No. Make sure that you do not consume any dairy foods such as cheese, butter, yoghurt or ice cream, milk or milk shakes 4 hours before taking this medicine or 2 hours after taking this medicine.

Can [GBNKYWORD] be used during pregnancy?

No. It is not recommended for use during pregnancy. Before starting the treatment, inform your doctor if you are pregnant.

How to take [GBNKYWORD]?

Take this medicine as directed by your physician. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results. Make sure that you do not consume any dairy foods such as cheese, butter, yoghurt or ice cream, milk or milk shakes 4 hours before taking this medicine or 2 hours after taking this medicine.

REFERENCES

1. Kenneth Kaushansky and Thomas J. Kipps. Hematopoietic agents, Goodman & Gilman’s: The Pharmacological basics of therapeutics. 12th Edition. New York Mc Graw Hill Medical 2011. Page - 1076.

2. Gerald G. Briggs and Roger K. Freeman. E. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 1325-1327.

3. University of Utah. Efficacy and Safety of Eltrombopag In Patients with Severe and Very Severe Aplastic Anemia. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on October 2017] [Accessed 29th October 2020] https://clinicaltrials.gov/ct2/show/NCT01703169

4. Jyothis Purushothaman, Kochuthresia J. Puthumana, Aswath Kumar, Susheela J. Innah and Sareena Gilvaz. A case of refractory immune thrombocytopenia in pregnancy managed with elthrombopag. NCBI; PMC National Library of Medicine, National Institute of Health. July-December 2016 [Accessed 29th October 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993088/#:~:text=Eltrombopag%20has%20been%20assigned%20to,only%20when%20benefit%20outweighs%20risk.

5. Novartis Farmacéutica SA. Electronic Medicines Compendium (EMC); [Revised on January 2020] [Accessed 29th October 2020] https://www.medicines.org.uk/emc/files/pil.7820.pdf

6. GlaxoSmithKline. U.S. Food & Drug Administration; [Revised on October 2008] [Accessed 29th October 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/022291lbl.pdf

USEFUL DIAGNOSTIC TESTS

  • Complete Blood Count
  • Iron Studies
  • Peripheral Smear Examination
  • Vitamin B12

VIDEOS

ELTROMBOPAG TABLET - Drug Information

ELTROMBOPAG TABLET : Therapeutic Uses, Warning and Precautions, Interactions, Directions for Use, Side Effects and Storage

Marketer DETAILS

    Country Of Origin
    India
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Revolade 25mg Tablet 7'S

Revolade 25mg Tablet 7'S Mfr: Novartis India Ltd

M.R.P.: Rs.7,597.00
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