INTRODUCTION

RELITIL INJECTION contains Chlorpromazine which belongs to the group of medicines called Antipsychotics. It is used to treat the following conditions such as schizophrenia and other psychoses (especially paranoid), mania and hypomania, anxiety psychomotor agitation excitement, violent or dangerously impulsive behaviour, intractable hiccup and nausea, vomiting of terminal illness (where other medicines have failed or are not available). It is also used to treat schizophrenia and autism (in children).

It is not recommended for use in patients with CNS depression, bone marrow depression and Phaeochromocytoma. Consult your doctor for advice before receiving the medicine.

Before receiving this medicine inform your doctor if you have heart diseases, liver disease or kidney problems, thyroid, epilepsy, and parkinson’s disease.

Pregnant and breastfeeding women should consult their doctors before receiving this medicine. Tell your doctor if you will be exposed to extreme heat, or to insecticide poisons while you are taking this medicine.

The most common side effects are drowsiness, dry mouth or stuffy nose, blurred vision, constipation and impotence. Consult your doctor if any of the above side effects gets worse.

USES OF RELITIL INJECTION

It is used to treat the following conditions:

• schizophrenia and other psychoses (especially paranoid), mania and hypomania
• anxiety psychomotor agitation excitement, violent or dangerously impulsive behaviour
• intractable hiccup
• nausea and vomiting of terminal illness (where other medicines have failed or are not available)
• schizophrenia and autism (in children)

HOW RELITIL INJECTION WORKS

RELITIL INJECTION exerts its antipsychotic effect by blocking postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby preventing the excess of dopamine in the brain.

DIRECTIONS FOR USE

RELITIL INJECTION will be administered intramuscularly or intravenously by your doctor or nurse. Your doctor will administer the correct dose for you depending upon your conditions.

SIDE EFFECTS OF RELITIL INJECTION

HOW TO MANAGE SIDE EFFECTS

Dry mouth:

Chew sugar-free gum. Control caffeine intake. Do not use mouthwashes. Sip water regularly.

Constipation:

Eat fiber rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before receiving RELITIL INJECTION tell your physician if you are taking any of the following medicine:

• benztropine (used to treat Parkinson’s disease)
• antacids (used to treat ulcers)
• lithium (used as mood stabilizers)
• ciprofloxacin (treats infection)
• fluvoxamine (treats OCD)
• oral contraceptives
• vemurafenib (used to treat cancer)
• oral anticoagulants (used to treat blood clot)
• guanethidine and clonidine
• quinidine, disopyramide, amiodarone and sotalol (treats heart disorders)
• bepridil, cisapride, sultopride, thioridazine, methadone
• intravenous erythromycin, intravenous vincamine
• halofantrine, pentamidine, sparfloxacin
• stimulant laxatives, intravenous amphotericin B
• glucocorticoids and tetracosactides
• other antipsychotic medicines

Overdosage:

RELITIL INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms. Symptoms of overdose includes dry mouth, bloating or stomach cramps, feeling restless, fever, muscle stiffness, jerky muscle movements, changes in heart rate, fainting, or seizure (convulsions).  

SYNOPSIS

MORE INFORMATION

• Keep out of reach of children
• Store at room temperature

FAQs ABOUT RELITIL INJECTION

Can I receive RELITIL INJECTION if I have kidney disease?

RELITIL INJECTION should be used with caution in patients suffering from kidney diseases. Consult your doctor before receiving this medicine.

Can I receive RELITIL INJECTION during breastfeeding?

No, it is not recommended for use in breast feeding women. Consult your doctor before receiving this medicine.

Can RELITIL INJECTION cause constipation?

Yes, this medicine may cause constipation in some individuals. Eat fiber rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

What does RELITIL INJECTION do to the brain?

RELITIL INJECTION exerts its antipsychotic effect by blocking postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby preventing the excess of dopamine in the brain. This leads to a reduction in psychotic symptoms.

Does RELITIL INJECTION cause any side effects?

The most common side-effects are feeling drowsy or dizzy, blurred vision and dry mouth. It may cause your skin to become more sensitive to sunlight than normal. Protect your skin from bright sunlight and do not use sunbeds.

Is RELITIL INJECTION benzodiazepine/sleeping medicine?

This medicine is not a benzodiazepine. It belongs to a class of medicines called phenothiazine antipsychotics. It should not be used as a sleeping medicine.

REFERENCES

1. Sukhmanjeet Kaur Mann; Raman Marwaha. Chlorpromazine. National Center for Biotechnology Information, U.S. National Library of Medicine. [Accessed 01 Dec 2021] https://www.ncbi.nlm.nih.gov/books/NBK553079/

2. Drugs.com. Chlorpromazine. [Accessed 01 Dec 2021] https://www.drugs.com/mtm/chlorpromazine.html

3. Webmed.com. Chlorpromazine. [Accessed 01 Dec 2021] https://www.webmd.com/drugs/2/drug-1444/chlorpromazine-oral/details

4. Sanofi-aventis New zealand limited. [Accessed 04 Feb 2013] [Accessed 01 Dec 2022] https://genesight.com/wp-content/uploads/2017/05/Chlorpromazine-Thorazine-FDA-Label.pdf