INTRODUCTION
RAVIER contains Rabeprazole which belongs to a group of medicine called Proton Pump Inhibitors (PPIs). It is used for the short-term treatment of gastric and duodenal ulcers, gastro-oesophageal reflux disease (GERD) and as an alternative to oral therapy in patients who are unable to take oral proton-pump inhibitor (PPI). Gastroesophageal reflux disease is a condition where the acid in the stomach acid frequently flows back into the oesophagus (a tube connecting your mouth and stomach). This acid reflux can irritate the lining of your esophagus.
A sore on the lining of your stomach, small intestine or oesophagus is called peptic ulcer. RAVIER works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn. It is not recommended for use in children. Consult your doctor for advice before taking RAVIER, if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.
USES OF RAVIER
- Used for the short-term treatment of gastric and duodenal ulcers, gastro-oesophageal reflux disease (GERD)
HOW RAVIER WORKS
RAVIER works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.
DIRECTIONS FOR USE
RAVIER must be administered by a doctor or nurse. It will be given to you as an injection into your vein. Your doctor will decide the correct dose for you depending on your condition.
SIDE EFFECTS OF RAVIER
SERIOUS
- allergic reactions such as sudden swelling of your face, breathing difficulty or low blood pressure which may cause fainting
- frequent infections
- ulcers in your mouth or throat
- bruising or bleeding
- sudden onset of severe rash or blistering or peeling skin
COMMON
- cough, runny nose, or sore throat (pharyngitis)
- stomach pain, diarrhoea, wind (flatulence), nausea and vomiting, constipation
- aches, back pain, non-specific pain
- weakness or flu-like symptoms
- difficulty sleeping
- headache, dizziness
- infections
- benign polyps in the stomach
RARE
- reduced number of white cells or platelets
- loss of appetite (anorexia)
- depression
- visual disturbance, taste disturbance
- inflammation of the liver
- itchy rash, sweating, skin blisters
- kidney inflammation (interstitial nephritis)
- increased weight
HOW TO MANAGE SIDE EFFECTS
Stomach pain:
Keep try to rest and relax. eat and drink slowly and smaller and frequent meals. Applying a heat pad or covered hot water bottle on your stomach may also help. If still pain persists, speak to your doctor.
Diarrhoea:
Drink lot of fluid such as water or squash, to avoid dehydration. Do not take any other medicines without talking to a doctor.
Nausea and vomiting:
Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
Constipation:
Take fibre rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.
Headache:
Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.
Dizziness:
Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.
WARNING & PRECAUTIONS
PREGNANCY
RAVIER is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
BREASTFEEDING
RAVIER is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
Do not drive or operate machinery while taking this medicine, since it may cause sleepiness.
ALCOHOL
Consumption of alcohol is not recommended during treatment with RAVIER.
KIDNEY
RAVIER should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.
LIVER
RAVIER should be taken with caution in patients with severe liver disease. Consult your doctor for advice.
ALLERGY
Do not take RAVIER if you are allergic (hypersensitive) to Rabeprazole or any other ingredients in this medicine.
OTHERS
Tell your doctor if you have or had a condition such as,
- stomach tumour
- reduced body stores or risk factor for reduced vitamin B12
INTERACTIONS
Talk to your doctor if you are taking,
- atazanavir (used to treat HIV-infection)
- ketoconazole or itraconazole (used to treat fungal infections)
- methotrexate (used to treat cancer)
SYNOPSIS
| Drug | : | Rabeprazole |
| Pharmacological Category | : | Proton Pump Inhibitors |
| Therapeutic Indication | : | Gastric and duodenal ulcers, gastro-oesophageal reflux disease (GERD) |
| Dosage Forms | : | Tablet, Capsule, Injection, Powder |
MORE INFORMATION
Store below 20-25°C and keep out of reach of children.
FAQs ABOUT RAVIER
Does RAVIER cause bone problems?
Yes, long term use of this medicine can cause thinning of bones which is called osteoporosis. This medicine will decrease the calcium absorption leading to calcium deficiency, and increases the risk of bone fractures of hip, wrist or spine. Take an adequate amount of calcium in your diet or take the supplements as advised by your doctor to avoid any bone problems.
What is the use of RAVIER?
It is used for the short-term treatment of gastric and duodenal ulcers, gastro-oesophageal reflux disease (GERD).
How do you take RAVIER?
It must be administered by a doctor or nurse. It will be given to you as an injection into your vein. Your doctor will decide the correct dose for you depending on your circumstance.
REFERENCES
1. KD Tripathi. Drugs for Peptic Ulcer and Gastroesophageal Reflux Disease. Essentials of Medical Pharmacology. Seventh Edition,2013. Page - 653.
2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page - 3338-3341.
3. Alia Dadabhai 1, Frank K Friedenberg. Rabeprazole: a pharmacologic and clinical review for acid-related disorders. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. Jan 2009. [Accessed 24 Nov 2020] https://pubmed.ncbi.nlm.nih.gov/19236223/
4. Cipla Ltd; [Revised on 30 Jun 2020] [Accessed 24 Nov 2020] https://www.ciplamed.com/content/rabicip-iv-injection
USEFUL DIAGNOSTIC TESTS
- Helicobacter pylori Test (H. pylori)
- Barium Swallow
- Upper endoscopy
PRODUCT DETAILS
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