Rapisone SR Capsule 5'S

INTRODUCTION

RAPISONE SR CAPSULE contains Eperisone, which belongs to the group of medicines called Muscle Relaxants. It is used to treat and improve the myotonic condition of the muscles caused by neck-shoulder arm syndrome (a condition causing muscle pain and stiffness in the neck, arm, and shoulder region), scapulohumeral periarthritis (a condition causing muscle pain and stiffness in the shoulder joint), and low back pain (a painful condition affecting the lower region of the spine due to a muscle or ligament injury).

The myotonic condition causes wasting and weakness of the muscle when its functional ability to relax is impaired. It is also used to treat spastic paralysis (loss of muscle function along with pain and muscle stiffness) caused by a spinal or neurological disorder, trauma, cerebral palsy, tumour in the spine, etc.

RAPISONE SR CAPSULE should be used with caution in patients with liver function disorders. RAPISONE SR CAPSULE is generally not recommended for use during pregnancy unless recommended by your doctor. RAPISONE SR CAPSULE is not recommended for use by breastfeeding women. Its safety and efficiency for use in children have not been established. Consult your doctor for advice before taking RAPISONE SR CAPSULE.

The most common side effects of taking RAPISONE SR CAPSULE may include weakness, light-headedness, fatigue, sleepiness, insomnia, headache, nausea, vomiting, loss of appetite, abdominal pain, diarrhea, constipation, and thirst. Consult your doctor if any of the above side effects worsen or persist.

USES OF RAPISONE SR CAPSULE

• Treats and improves the myotonic condition (wasting and weakness) of the muscle
• Treats spastic muscle paralysis

HOW RAPISONE SR CAPSULE WORKS

RAPISONE SR CAPSULE works by blocking the voltage-gated sodium channel in the brain stem. As a result, it stops nerve signals and aids in the relaxation of muscles.

DIRECTIONS FOR USE

Take RAPISONE SR CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose, frequency, and duration of treatment for you depending upon your age, body weight, and disease condition.

SIDE EFFECTS OF RAPISONE SR CAPSULE

HOW TO MANAGE SIDE EFFECTS

Nausea, vomiting:

Take this medicine with or just after the meal. Stick to simple meals. Avoid eating oily or spicy foods.

Headache:

Rest and relax. Drink plenty of fluids such as water or electrolytes and apply a pain-relieving balm to the head if necessary. Do not consume alcohol. Contact your doctor if your symptom worsens or persists.

Diarrhoea:

Drink lots of fluids, such as water or fruit juices, to keep you hydrated. Do not take any medicine on your own to treat diarrhoea. Contact your doctor if your symptom worsens or persists.

Constipation:

Eat plenty of fiber-rich foods such as fresh fruits and vegetables, cereals, and drink water. Exercise regularly. Contact your doctor if your symptom worsens or persists.

Stomach pain:

Try to rest and relax. Eat small meals but take them frequently. Keep a heating pad on your stomach to ease the pain. Contact your doctor if the symptom does not improve.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating machines if you feel dizzy. Contact your doctor if your symptom worsens or persists.

WARNING & PRECAUTIONS

PREGNANCY

RAPISONE SR CAPSULE is generally not recommended for use during pregnancy unless recommended by your doctor. Contact your doctor before taking RAPISONE SR CAPSULE.

BREASTFEEDING

RAPISONE SR CAPSULE is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking RAPISONE SR CAPSULE.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel weakness, sleepiness, or light-headedness after taking RAPISONE SR CAPSULE.

LIVER

RAPISONE SR CAPSULE should be used with caution in patients with a disorder of liver function. Consult your doctor before taking RAPISONE SR CAPSULE.

ALLERGY

RAPISONE SR CAPSULE is not recommended for use if you are allergic to Eperisone.

INTERACTIONS

A. Drug-Drug interactions:

• methocarbamol (a medicine used to treat muscle spasms or stiffness)

Overdosage:

If you or anyone else have accidentally taken too much of RAPISONE SR CAPSULE, consult your doctor immediately or visit the nearby hospital as overdosage can result in abnormal heart function.

SYNOPSIS

MORE INFORMATION

• keep RAPISONE SR CAPSULE out of reach from children
• store at room temperature

FAQs ABOUT RAPISONE SR CAPSULE

Can RAPISONE SR CAPSULE be used to treat muscle pain?

Yes, RAPISONE SR CAPSULE relieves muscle pain and relaxes the muscle by blocking the voltage-gated sodium channel in the brain stem, thereby stopping the conduction of nerve signals.

Can RAPISONE SR CAPSULE be used in pregnant and nursing mothers?

RAPISONE SR CAPSULE is generally not recommended for use during pregnancy unless considered necessary by your doctor. RAPISONE SR CAPSULE is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking it.

Can RAPISONE SR CAPSULE cause dizziness?

Yes, RAPISONE SR CAPSULE may cause dizziness. If you start to feel dizzy, sit down immediately or lay down in a quiet and dark area with your eyes closed. Consult your doctor if the symptom worsens or persists.

Can RAPISONE SR CAPSULE be taken by patients with liver disease?

RAPISONE SR CAPSULE should be used with caution in patients having a liver function disorder, as this medicine may aggravate the existing condition. Consult your doctor for advice.

How does RAPISONE SR CAPSULE work?

RAPISONE SR CAPSULE works by blocking the voltage-gated sodium channel in the brain stem. As a result, it stops nerve signals and aids in the relaxation of muscles.

REFERENCES

1. Kamran Ahmed, Muhammad Harris Shoaib, Rabia Ismail Yousuf, Fahad Siddiqui, Faaiza Qazi, Javeria Iftikhar, Farrukh Rafiq Ahmed, and Muhammad Iqbal Nasiri. Comparative pharmacokinetics of osmotic-controlled and immediate-release Eperisone tablet formulation in healthy human subjects using a sensitive plasma LC-ESI-MS/MS method. National Institute of Health. NLM. National Centre for Biotechnology Information. Pubmed.gov. October 2020. [Accessed 7th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002734/

2. Takeshi Yamagiwa, Seiji Morita, Mari Amino, Naoya Miura, Takeshi Saito, Sadaki Inokuchi. Serum concentration of eperisone hydrochloride correlates with QT interval. National Institute of Health. NLM. National Centre for Biotechnology Information. Pubmed.gov. January 2014. [Accessed 7th June 2022] https://pubmed.ncbi.nlm.nih.gov/24135462/

3. Rizaldy Taslim Pinzon, Vincent Ongko Wijaya, Dessy Paramitha, and Raymondus Ranga Bagaskara. Effects of Eperisone Hydrochloride and Non-Steroid Anti-Inflammatory Drugs for Acute Non-Specific Back Pain with Muscle Spasm: A Prospective, Open-Label Study. National Institute of Health. NLM. National Centre for Biotechnology Information. Pubmed.gov. November 2020. [Accessed 7th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678690/

4. Eisai Co., Ltd. [Revised in July 2009] [Accessed 7th June 2022] http://www.shijiebiaopin.net/upload/product/201082521391314.pdf

AUTHOR DETAILS

Written By Dr. Dhivakaran R, BDS
Last updated on 30 Sep 2022 | 11:53 AM(IST)