Pyrakem 1000mg Injection 100ml

Fever Rx required

Best Price* ₹ 290.40 MRP ₹ 363.00
(Inclusive of all taxes) * Mkt: Alkem Laboratories Ltd (Generics) * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

PYRAKEM 1000MG INJECTION contains Paracetamol which belongs to the group of medicines called Analgesics and Antipyretics. It is used for short-term treatment of moderate pain (especially after surgery) and fever when administered by the intravenous route is clinically justified.

Before receiving PYRAKEM 1000MG INJECTION, inform your doctor if you have heart, lung, liver or kidney problems or if you suffer from alcoholism or alcohol abuse, malnourishment and severely low blood volume due to dehydration or blood loss.

PYRAKEM 1000MG INJECTION should be used with caution in pregnant and breastfeeding women only if clearly advised by the doctor. PYRAKEM 1000MG INJECTION should be used with caution in children and elderly patients.

The most common side effects of receiving PYRAKEM 1000MG INJECTION are nausea, vomiting, headache, sleep problems and itching. Inform your doctor if any of these side effect worsens.

USES OF PYRAKEM 1000MG INJECTION

  • For short-term treatment of moderate pain (especially after surgery) and fever

HOW PYRAKEM 1000MG INJECTION WORKS

GBNKEYWORD] relieves pain by increasing the pain threshold by inhibiting certain enzymes (COX-1 and COX-2) involved in the synthesis of chemicals responsible for inducing pain (prostaglandins). It reduces fever by directly acting on heat-regulating centers in the brain, resulting in vessel relaxation, sweating and loss of body heat.

DIRECTIONS FOR USE

PYRAKEM 1000MG INJECTION will be given to you only by a doctor or a nurse into the vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you based upon your age, body weight and disease condition.

SIDE EFFECTS OF PYRAKEM 1000MG INJECTION

COMMON

  • nausea, vomiting, constipation
  • headache
  • sleep problems
  • itching

RARE

  • feeling generally unwell
  • drop in blood pressure
  • abnormal levels of liver enzymes

Inform your doctor immediately if you experience any of the following side effects while receiving PYRAKEM 1000MG INJECTION:

  • serious allergic reaction or skin rash

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Stick to simple meals while receiving this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Inform your doctor if the symptom does not improve.

Constipation:

Try to eat more high-fibre foods such as fresh fruit, vegetables, cereals and drink plenty of water. If this does not help, inform your doctor to receive alternate treatment for constipation.

Headache:

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress-free. Apply pain relieving balm on your forehead if necessary. Inform your doctor if the symptom does not improve.

WARNING & PRECAUTIONS

PREGNANCY

PYRAKEM 1000MG INJECTION should be used with caution in pregnant women only if considered clearly necessary. Your doctor may use the lowest possible dose to reduce the pain and fever only for shorter duration in pregnant women. Consult your doctor before receiving it.

BREASTFEEDING

PYRAKEM 1000MG INJECTION can be used in breastfeeding women only if considered clearly necessary. Consult your doctor before receiving it.

ALCOHOL

PYRAKEM 1000MG INJECTION should be used with caution in patients with alcoholism or those who suffer from alcohol abuse.

KIDNEY

PYRAKEM 1000MG INJECTION should be used with caution in patients with kidney disease. Consult your doctor before receiving it.

LIVER

PYRAKEM 1000MG INJECTION is not recommended for use in patients with severe liver disease. It should be used with caution in patients with liver disease. Consult your doctor before receiving it.

ALLERGY

Do not receive PYRAKEM 1000MG INJECTION if you are allergic to Paracetamol, propacetamol or any other ingredients of this medicine.

LUNGS

Repeated use of PYRAKEM 1000MG INJECTION is not recommended for use in patients with lung disease. Consult your doctor before receiving it.

OTHERS

PYRAKEM 1000MG INJECTION is not recommended for use if you:

  • have anaemia

Before receiving PYRAKEM 1000MG INJECTION, inform your doctor if you:

  • have severe hypovolemia (low blood volume due to dehydration or blood loss)
  • have chronic malnutrition

Use in pediatrics:

PYRAKEM 1000MG INJECTION should be used with caution in children and your child’s doctor may adjust the dose depending upon the child’s age and body weight. Consult your child’s doctor for advice before administration of PYRAKEM 1000MG INJECTION.

Use in geriatrics:

PYRAKEM 1000MG INJECTION should be used with caution in elderly patients. Consult your doctor before receiving it.

INTERACTIONS

A. Drug - Drug interactions:

Before receiving PYRAKEM 1000MG INJECTION, inform your doctor if you are taking any of the following medicines:

  • other medicines containing paracetamol or propacetamol
  • probenecid (used to treat gout)
  • medicines used for blood thinning (Ex. warfarin)

Overdosage:

PYRAKEM 1000MG INJECTION will be administered to you only by a doctor or a nurse in a hospital and so it is unlikely to receive an overdose. However, consult your doctor if you experience any unusual symptoms such as nausea, vomiting, anorexia (eating disorder), paleness, stomach pain and a risk of liver injury.

SYNOPSIS

Drug :   Paracetamol
Pharmacological Category :   Para aminophenol derivative
Therapeutic Indication :   Pain, Fever
Dosage Forms :  

Tablet, Dispersible tablet, Drops, Syrup, Oral suspension, Liquid, Oral solution, Suppositories, Infusion, Injection

MORE INFORMATION

Store below 25°C

FAQs ABOUT PYRAKEM 1000MG INJECTION

What is PYRAKEM 1000MG INJECTION used for?

PYRAKEM 1000MG INJECTION is used for short-term treatment of moderate pain (especially after surgery) and fever and when administered by the intravenous route is clinically justified. Consult your doctor for advice before administration of PYRAKEM 1000MG INJECTION.

What should I tell my doctor before receiving PYRAKEM 1000MG INJECTION?

Patients receiving PYRAKEM 1000MG INJECTION must inform their doctor about pre-existing conditions like heart, lung, liver or kidney problems, alcoholism, malnourishment or dehydration. Patients should also inform the doctor if they are pregnant, breastfeeding or allergic to anything. Inform your doctor if you experience any unusual symptoms during treatment with this medicine.

Can PYRAKEM 1000MG INJECTION be used during pregnancy?

PYRAKEM 1000MG INJECTION should be used with caution in pregnant women only if clearly advised by the doctor. Your doctor may use the lowest possible dose to reduce the pain and fever only for a shorter duration in pregnant women. Consult your doctor before receiving PYRAKEM 1000MG INJECTION.

How does PYRAKEM 1000MG INJECTION work?

PYRAKEM 1000MG INJECTION relieves pain by increasing the pain threshold by inhibiting certain enzymes (COX-1 and COX-2) involved in the synthesis of chemicals responsible for inducing pain (prostaglandins). It reduces fever by directly acting on heat-regulating centers in the brain, resulting in vessel relaxation, sweating and loss of body heat.

Is PYRAKEM 1000MG INJECTION safe to use in patients with liver disease?

PYRAKEM 1000MG INJECTION is not recommended for use in patients with severe liver disease. It should be used with caution in patients with liver disease. Your doctor may monitor your liver function test before and during treatment with this medicine to prevent the risk of liver damage. Consult your doctor before receiving PYRAKEM 1000MG INJECTION.

REFERENCES

1. Tilo Grosser, Emer Smyth and Garret A. FitzGerald. Anti-inflammatory, Antipyretic and Analgesic agents; Pharmacotherapy of gout. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 693.

2. KD. Tripathi. NSAIDs and Antipyretic-Analgesics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 206.

3. Ulderico Freo, Chiara Ruocco, Alessandra Valerio, Irene Scagnol and Enzo Nisoli. Paracetamol: A Review of Guideline Recommendations. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. August 2021. [Accessed on 16th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347233/

4. Olivier Malaise, Olivier Bruyere and Jean-Yves Reginster. Intravenous paracetamol: A review of efficacy and safety in therapeutic use. ResearchGate. November 2007. [Accessed on 16th August 2022] https://www.researchgate.net/publication/247872458_Intravenous_paracetamol_A_review_of_efficacy_and_safety_in_therapeutic_use

5. Altan Pharmaceutical. Electronic Medicines Compendium (EMC). [Revised in December 2021] [Accessed on 16th August 2022] https://www.medicines.org.uk/emc/files/pil.13649.pdf

6. B. Braun Medical Inc. U.S. Food & Drug Administration. [Revised in February 2021] [Accessed on 16th August 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/204957s000lbl.pdf

7. Therapeutic Pharmaceuticals. Aeknil injection (Paracetamol). [Revised in May 2016] [Accessed on 16th August 2022] https://aeknil.com/pi/aekinj.pdf

8. Central Drugs Standard Control Organization (CDSCO). Paracetamol. [Accessed on 16th August 2022] https://cdscoonline.gov.in/CDSCO/Drugs

USEFUL DIAGNOSTIC TESTS

  • Complete blood count
  • Liver function test

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    120 g
    Ingredient
    PARACETAMOL(ACETAMINOPHEN) 1000MG
    Hsn Code
    30049069
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