INTRODUCTION
PULMOSIL 10MG contains Sildenafil which belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors. It is used to treat pulmonary arterial hypertension which decreases high pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries). It is used for the treatment of patients with PAH who are currently prescribed oral sildenafil and who are temporarily unable to take oral medication.
Tell your doctor if you have severe heart or liver problems, if you have recently had a stroke or heart attack or if you have low blood pressure. It helps to improve your exercise ability. It is given under the supervision of a physician. It is not recommended for use in children and adolescents below 18 years. The common side effects are flushing, headache, stiffness, nosebleeds, blurred vision and muscle pain.
USES OF PULMOSIL 10MG
- Treats pulmonary arterial hypertension
HOW PULMOSIL 10MG WORKS
Sildenafil works by relaxing the blood vessels in your lungs thereby reducing the high blood pressure in the lungs. This allows your heart to work less to pump blood in your lungs.
DIRECTIONS FOR USE
PULMOSIL 10MG is given by a doctor or nurse. Your healthcare provider will administer this injection depending on your age, body weight and health condition.
SIDE EFFECTS OF PULMOSIL 10MG
COMMON
- flushing (sense of warmth in the face, ears, neck and trunk)
- headache
- stiffness
- nosebleeds
- blurred vision
- muscle pain
HOW TO MANAGE SIDE EFFECTS
Headache:
Rest and drink plenty of fluids.
WARNING & PRECAUTIONS
PREGNANCY
PULMOSIL 10MG should be used with caution if you are pregnant, or if you are trying to become pregnant. Consult your doctor for advice.
BREASTFEEDING
PULMOSIL 10MG should be used with caution if you are breastfeeding. Consult your doctor for advice.
DRIVING AND USING MACHINES
PULMOSIL 10MG may cause dizziness or altered vision. Do not drive or handle any machines while receiving this medicine.
ALCOHOL
Do not drink excessive amounts of alcohol while receiving this medicine.
KIDNEY
PULMOSIL 10MG should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.
LIVER
PULMOSIL 10MG is not recommended in patients with severe liver disease. Consult your doctor for advice.
ALLERGY
Do not take if you are allergic (hypersensitive) to Sildenafil or any other ingredients in this medicine.
HEART DISEASE
PULMOSIL 10MG is not recommended in patients with severe heart disease. Consult your doctor for advice.
OTHERS
Tell your doctor if you have or had a condition such as,
- low blood pressure
- inherited eye diseases (retinitis pigmentosa)
- loss of vision
- deformity of your penis or Peyronie’s disease
- stomach ulcer or bleeding problem (haemophilia)
- severe hypotension
INTERACTIONS
Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:
- nitroglycerin
- amyl nitrite
- riociguat (used to treat pulmonary arterial hypertension)
- protease inhibitors (used to treat HIV)
- CYP3A4 inhibitors (ketoconazole, itraconazole, ritonavir)
SYNOPSIS
| Drug | : | Sildenafil |
| Pharmacological Category | : | Phosphodiesterase-5 Enzyme Inhibitor |
| Therapeutic Indication | : | Pulmonary arterial hypertension |
| Dosage Forms | : | Tablet, Injection, Oral suspension |
MORE INFORMATION
Store below 20-25°C and keep out of reach of children.
FAQs ABOUT PULMOSIL 10MG
Is PULMOSIL 10MG safe to use in patients with diabetes?
Yes, if prescribed by your doctor then this medicine is safe to use in patients with diabetes.
Why is the use of PULMOSIL 10MG contraindicated with nitrates?
It is harmful for patients taking nitrates or blood pressure-lowering medicines as their combined use can cause a severe fall in blood pressure. These medicines are to be taken together then it is advised to keep a time gap of 24 hours.
Can I get PULMOSIL 10MG without a prescription?
No, you need a doctor's prescription to get this medicine since it is a prescription medicine. Your doctor will prescribe it only if it would be beneficial for you.
REFERENCES
1. KD Tripathi MD. Hormones and related drugs. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 304.
2. Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page 752-53.
3. Christopher F Barnett and Roberto F Machado. Sildenafil in the treatment of pulmonary hypertension: Vascular health and risk management. Dec, 2006. [Accessed Oct 5, 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994020/
4. Ciplamed. April 20, 2018. [Accessed Oct 5, 2020] https://www.ciplamed.com/printpdf/37369
Manufacturer/Marketer Details
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