INTRODUCTION
PROPYNATE CREAM contains Betamethasone, which belongs to the group of medicines called Corticosteroids. It is used to reduce the redness and itchiness of certain skin problems like eczema (patches of rough and scaly skin with blisters), psoriasis (scales and itchy dry patches due to build-up of skin cells), and dermatitis (inflammation of the skin).
Do not smoke or go near naked flames after applying PROPYNATE CREAM, as it is inflammable. PROPYNATE CREAM is not recommended to use in patients having several skin conditions like acne, severe flushing of skin on and around the nose (rosacea), spotty red rash around the mouth (perioral dermatitis), itching around the back passage or private parts, infected skin, and itchy skin which is not inflamed.
Before using PROPYNATE CREAM, inform your doctor if you have a chronic leg ulcer, psoriasis or infection of the skin. PROPYNATE CREAM should be used with caution among women who are pregnant or breastfeeding. PROPYNATE CREAM is not recommended for use in children less than 1 year of age.
The most common side effects of using PROPYNATE CREAM are application site reactions like the feeling of burning, pain, irritation or itching. Contact your doctor if any of the above symptoms worsen.
USES OF PROPYNATE CREAM
It reduces the redness and itchiness of certain skin problems like:
- eczema
- psoriasis
- dermatitis
HOW PROPYNATE CREAM WORKS
PROPYNATE CREAM works by acting inside skin cells and preventing the release of certain chemical messengers in the body that cause redness, itching, and swelling. When the skin reacts to any kind of allergens, such chemicals are released normally.
DIRECTIONS FOR USE
Always apply PROPYNATE CREAM as directed by your physician. It is for external use only. Apply a thin layer of PROPYNATE CREAM to the affected area. Avoid applying this medicine around your eyes, including your eyelids. Your doctor will decide the correct dose and duration of PROPYNATE CREAM depending upon your age, weight and health condition.
SIDE EFFECTS OF PROPYNATE CREAM
COMMON
- application site reactions like the feeling of burning, pain, irritation or itching
RARE
Stop using PROPYNATE CREAM and contact your physician immediately if you experience any of the following side effects:
- worsening of skin conditions such as generalized rash or the skin becomes swollen
- raised bumps with pus under the skin
- blurred vision or other visual disturbances (using near eyes may result in entering of the medicine in the eyes causing glaucoma or cataract)
HOW TO MANAGE SIDE EFFECTS
Skin irritation
Avoid hot bathing because hot water can irritate your skin further. Do not scratch the affected area. Use comfortable clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if the symptoms don’t improve or worsen.
WARNING & PRECAUTIONS
PREGNANCY
PROPYNATE CREAM should be used with caution in pregnant women. Consult your doctor before using PROPYNATE CREAM.
BREASTFEEDING
PROPYNATE CREAM should be used with caution in breastfeeding women. Consult your doctor before using PROPYNATE CREAM.
ALLERGY
Do not use PROPYNATE CREAM if you are allergic to Betamethasone or any of the other ingredients of this medicine.
OTHERS
PROPYNATE CREAM is not recommended for use if you have:
- acne
- severe reddening of the skin on and around the nose (rosacea)
- spotty red rash across the mouth (perioral dermatitis)
- itching around the back passage or private parts
- infected skin
- itchy skin which is not inflamed
Before using PROPYNATE CREAM, inform your doctor if you:
- are using PROPYNATE CREAM for chronic leg ulcer
- have to apply on a large area
- have psoriasis
- have to apply on broken skin or within skin folds
- have to apply on eyelids or near eyes
- have a skin infection
- are applying on face
Use in pediatrics:
PROPYNATE CREAM is not recommended to use in children below 1 year of age. Consult your child’s doctor before using PROPYNATE CREAM.
Use in geriatrics:
There is no information on the use of PROPYNATE CREAM in elderly patients. Consult with your doctor before using PROPYNATE CREAM.
INTERACTIONS
A. Drug-Drug interactions:
Before using PROPYNATE CREAM, inform your doctor if you are taking any of the following medicine:
- medicine used to treat Human Immunodeficiency Virus (HIV) (Ex. ritonavir)
- medicine used to treat fungal infection (Ex. itraconazole)
Overdosage
If you or anyone else accidentally ingests or use too much of PROPYNATE CREAM, consult your doctor immediately or visit the nearby hospital as it can make you ill.
SYNOPSIS
| Drug | : | Betamethasone |
| Pharmacological Category | : | Corticosteroids |
| Therapeutic Indication | : | Ecezma, Psoriasis, Dermatitis |
| Dosage Forms | : | Tablet, Gel, Cream, Ointment, Lotion, Oral drops, Oil, Eye/Ear drops, Injection |
MORE INFORMATION
- Keep PROPYNATE CREAM out of reach from children
- Store at a temperature not more than 25°C
FAQs ABOUT PROPYNATE CREAM
How to use PROPYNATE CREAM?
Always apply PROPYNATE CREAM as directed by your physician. It is for external use only. Apply a thin layer of PROPYNATE CREAM to the affected area. Treated areas on the face should not be covered with a plaster or bandage. Do not use this medicine on your face for more than 5 days. Avoid applying this medicine around your eyes, including your eyelids.
What if I forget to use a dose of PROPYNATE CREAM?
If you forget a dose of PROPYNATE CREAM, apply it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and apply the next scheduled dose at the prescribed time.
Is it safe to use PROPYNATE CREAM during pregnancy and breastfeeding?
GBNKEYWORD] should be used with caution in pregnant women and breastfeeding women unless considered clearly necessary. Consult your doctor before using PROPYNATE CREAM.
When PROPYNATE CREAM is not recommended?
PROPYNATE CREAM is not recommended to use in patients having several skin conditions like acne, severe flushing of skin on and around the nose (rosacea), spotty red rash around the mouth (perioral dermatitis), itching around the back passage or private parts, infected skin, and itchy skin which is not inflamed. It is also not recommended to use in children below 1 year of age. Please consult your doctor before using PROPYNATE CREAM.
Is PROPYNATE CREAM safe for use by children?
PROPYNATE CREAM is generally not recommended for use in children under 1 year of age. Consult with your child’s doctor before using PROPYNATE CREAM.
Does PROPYNATE CREAM cause skin irritation?
Yes. Skin irritation is the most common side effect of PROPYNATE CREAM. Avoid hot baths, as hot water can irritate your skin further. Do not scratch the affected area. Use comfortable clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if the symptoms get worse or persist.
Can I stop using PROPYNATE CREAM on my own?
It is very important to keep using PROPYNATE CREAM till the time your doctor has prescribed it to you. Do not stop taking it on your own even if your symptoms lessen and you feel better. If you stop using PROPYNATE CREAM suddenly, your condition may get worse. Consult with your doctor if you wish to discontinue using PROPYNATE CREAM.
Can I start using PROPYNATE CREAM in case of a reoccurrence of my condition?
If you experience a recurrence of your condition shortly after stopping treatment with PROPYNATE CREAM, within 2 weeks, do not restart using PROPYNATE CREAM without consulting a doctor. If your condition has resolved and on recurrence the redness extends beyond the initial affected area and there is a burning sensation, please seek medical advice before restarting treatment.
What precautions should be taken while using PROPYNATE CREAM?
Do not smoke or go near naked flames while getting treated with PROPYNATE CREAM due to the risk of severe burns. Fabric (clothing, bedding, dressing, etc.) that has been in contact with PROPYNATE CREAM burns more easily and is a serious fire hazard.
REFERENCES
1. KD Tripathi. Corticosteroids. Drugs Essentials of medical pharmacology. 7th edition. 2013. Page – 289.
2. Sanaa A El-Gizawy, Maha Fadel, Basma Mourad, and Fatma El-zahraa Abd Elnaby. Betamethasone Dipropionate for Treatment of Localised Plaque Psoriasis. International Journal of Pharmacy and Pharmaceutical Sciences. Research gate. August 2017 [Accessed on 18th August 2022] https://www.researchgate.net/publication/318834216
3. Betamethasone. NIH National Library of Medicine, National center for biotechnology information. Pubchem. [Revised in August 2022] [Accessed on 18th August 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Betamethasone
4. Merck & Co., Inc. US Food and Drug Administration. [Revised in May 2019] [Accessed on 18th August 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/018741s040lbl.pdf
5. Glaxo Wellcome UK Ltd. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 18th August 2022] https://www.medicines.org.uk/emc/files/pil.930.pdf
6. Merck Canada Inc. [Revised in May 2020] [Accessed on 18th August 2022] https://pdf.hres.ca/dpd_pm/00057419.PDF
7. Glaxo Wellcome Operations. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 18th August 2022] https://www.medicines.org.uk/emc/files/pil.932.pdf
8. MIMS. Diprovate-RD (beclomethasone). [Accessed on 18th August 2022] https://www.mims.com/india/drug/info/diprovate-rd
USEFUL DIAGNOSTIC TESTS
- Absolute Eosinophil Count
- Peripheral Smear Examination
- Total IgE
PRODUCT DETAILS
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