PROLET 50 Tablet 15's

Epilepsy/Convulsion Rx required

Best Price*  ₹ 103.66
MRP ₹129.58
(Inclusive of all taxes) *15 Tablet(s) in a Strip * Mkt: Alteus Biogenics Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

PROLET 50 contain primidone which belongs to a group of medicine called barbiturate anticonvulsants. It is used for the treatment of certain types of epilepsy, seizures (fits) or shaking attacks (essential tremor).

Epilepsy is a disorder of the brain characterized by repeated seizure. A seizure is usually defined as a sudden alteration of behavior due to a temporary change in the electrical functioning of the brain. Epilepsy also called as seizure disorder.

The common side effects are lack of energy (apathy), coordination disorders, visual disturbances, rolling of the eyes, nausea. PROLET 50 controls seizures (fits) or epilepsy or shaking attacks (essential tremor) by increasing the action of GABA, a chemical messenger that suppresses the abnormal and excessive activity of the nerve cells in the brain.

Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.

USES OF PROLET 50

  • Treat certain types of epilepsy, seizures (fits) or shaking attacks (essential tremor)

HOW PROLET 50 WORKS

PROLET 50 controls seizures (fits) or epilepsy or shaking attacks (essential tremor) by increasing the action of GABA, a chemical messenger that suppresses the abnormal and excessive activity of the nerve cells in the brain.

DIRECTIONS FOR USE

Always take PROLET 50 exactly as your doctor has told you. PROLET 50 can be taken with or without food. Try to take this medicine at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine.

SIDE EFFECTS OF PROLET 50

COMMON

  • lack of energy (apathy), coordination disorder, visual disturbance, rolling of the eye
  • nausea

RARE

  • decreased number of some blood cells (red blood cells or white blood cells or platelets) or development of lymph nodes
  • changes in mood or behaviour
  • joint or bone pain, dupuytren’s contracture, osteomalacia
  • exfoliative dermatitis, lupus erythematous
  • raised levels of enzymes in your liver

HOW TO MANAGE SIDE EFFECTS

Nausea:

Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

WARNING & PRECAUTIONS

PREGNANCY

PROLET 50 is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING

PROLET 50 is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or operate any machine while taking this medicine, it may cause sleepiness.

ALCOHOL

Consumption of alcohol is not recommended during treatment with PROLET 50.

KIDNEY

PROLET 50 should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.

LIVER

PROLET 50 should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.

ALLERGY

Do not take PROLET 50 if you are allergic (hypersensitive) to primidone or any other ingredients in this medicine.

LUNGS

PROLET 50 should be used with caution in patients suffering from active lung diseases. Consult your doctor for advice.

OTHERS

Tell your doctor if you have or had a condition such as,

  • have porphyria (a rare inherited disorders of metabolism) or anyone in your family has it
  • seizures frequency increases or different type seizures appear
  • have had thoughts of harming or killing themselves
  • have developed Stevens-Johnson syndrome or toxic epidermal necrolysis
  • develop a rash

INTERACTIONS

Talk to your doctor if you are taking,

  • medicines such as phenytoin, felbamate, valproic acid, carbamazepine, perampanel, lamotrigine, oxcarbazepine, stiripentol, tiagabine, zonisamide (used to treat epilepsy and other types of seizures)
  • anticoagulants such as acenocoumarol, fluindione, phenindione, warfarin, apixaban, dabigatran, rivaroxaban or ticagrelor (used to prevent blood clots)
  • medicine such as methadone, oxycodone, or fentanyl (used to treat severe pain, cough, or as a substitute for morphine addiction)
  • antibiotics such as metronidazole, doxycycline, telithromycine
  • asthma medicines such as theophylline, montelukast
  • hormone containing medicine such as the oral contraceptive pill, estroprogestatives, progestatives, ulipristal
  • thyroid hormones
  • medicines such as beta-blockers, nimodipine, class IA antiarythmics, calcium antagonists, bosentan, dronedarone, ivabradine, macitentan, propafenone, ranolazine (used to treat heart disease, high blood pressure or regulate cardiac rhythms)
  • immune suppressants such as cyclosporine, tacrolimus, sirolimus, everolimus (used to prevent rejection of an organ transplant and also for other diseases of the body’s immune system)
  • anti-fungal medicines such as voriconazole, albendazole, itraconazole, posaconazole
  • folates (vitamin B9)
  • deferasirox (iron-chelator)
  • ivacaftor (used to treat cystic fibrosis)
  • antiparasite agent such as albendazole, praziquantel

SYNOPSIS

Drug :   Primidone
Pharmacological Category :   Anticonvulsant, Miscellaneous, Barbiturate
Therapeutic Indication :   Epilepsy, seizures (fits) or shaking attacks (essential tremor)
Dosage Forms :   Tablet

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT PROLET 50

Does PROLET 50 affect blood pressure?

No, it does not have any effect on blood pressure.

How should I store PROLET 50?

Keep this medicine out of reach of children and store below 25°C.

Can PROLET 50 cause nausea?

Yes, this medicine may cause nausea in some individuals. Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

REFERENCES

1. KD Tripathi. Antiepileptic Drugs. Essentials of Medical Pharmacology. Seventh Edition, 2013. Page - 413.

2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page - 3229-3233.

3. Naresh Lenkapothula; Marco Cascella. Primidone. US National Library of Medicines, National Institutes of Health. 20 Aug 2020. [Accessed 22 Jan 2021] https://www.ncbi.nlm.nih.gov/books/NBK562297/

4. Recipharm Limited, Sep 2019; Electronic Medicines Compendium (EMC); [Accessed 22 Jan 2021] https://www.medicines.org.uk/emc/files/pil.2941.pdf

PRODUCT DETAILS

    Net Qty
    1 N
    Hsn Code
    30049099
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ALTERNATE BRANDS
EPIAD 50 Tablet 10's
Prescription Epilepsy/Convulsion Rx required
Rs.99.00
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PROLET 50 Tablet 15's

PROLET 50 Tablet 15's Mkt: Alteus Biogenics Pvt Ltd

M.R.P.: Rs.129.58
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