INTRODUCTION
PRODROX 125 TABLET contains Cefadroxil which belongs to the group of medicines called Cephalosporin antibiotics. It is used in children to treat bacterial infections of the throat and upper part of the respiratory tract, skin and soft tissues, and the urinary tract. A bacterial infection can be defined as a proliferation of various harmful strains of bacteria in the body. They can affect any part(s) of the body including the respiratory tract, urinary tract, eyes, ears, skin, soft tissue, or bones.
PRODROX 125 TABLET must be taken with meals to avoid unwanted gastrointestinal side effects. Your doctor will decide the suitable dose for your child depending upon their age, body weight and severity of the infection.
Make sure that your child does not miss a dose of PRODROX 125 TABLET, as it may lead to growth of harmful bacteria within their body which cannot be further controlled by PRODROX 125 TABLET.
PRODROX 125 TABLET should not be used if your child is allergic to penicillin antibiotics (such as amoxicillin, ampicillin) or has severe kidney impairment. It is also important to inform your doctor if your child is going to undergo any blood test or urine test while undergoing therapy with PRODROX 125 TABLET.
The most common side effects of taking PRODROX 125 TABLET are nausea, vomiting, stomach pain and diarrhea. These side effects may probably reduce if PRODROX 125 TABLET is taken along with meals. However, consult your doctor if any of these side effect bothers your child.
USES OF PRODROX 125 TABLET
It is indicated for the treatment of the following bacterial infections in young children (who weigh less than 40 kg):
- throat infections (such as pharyngitis and tonsillitis)
- respiratory infections (such as pneumonia)
- urinary tract infections (such as cystitis or pyelonephritis)
- skin and soft tissue infections (such as abscesses, furunculosis, impetigo, erysipelas, pyoderma, lymphadenitis)
HOW PRODROX 125 TABLET WORKS
PRODROX 125 TABLET kills harmful bacteria where cefadroxil binds to the bacterial cell and interferes with the formation of bacterial cell wall. As a result, it weakens the bacterial cells and causing lysis of the bacteria.
DIRECTIONS FOR USE
Take PRODROX 125 TABLET as advised by your physician. Disperse the medicine in boiled and cool water immediately before consumption. PRODROX 125 TABLET must be taken with meals to avoid unwanted gastrointestinal side effects. Your doctor will decide the suitable dose and duration of therapy for your child depending upon their age, body weight and severity of infection.
It is important to take the full course of PRODROX 125 TABLET without any interruption. Therefore, make sure that your child does not miss a dose of PRODROX 125 TABLET, as it may lead to growth of harmful bacteria within their body which cannot be further controlled by PRODROX 125 TABLET.
SIDE EFFECTS OF PRODROX 125 TABLET
COMMON
- nausea, vomiting
- diarrhoea, indigestion, stomach pain
- skin rash with itching
- swollen sore tongue
UNCOMMON
- vaginal fungal infections or ‘thrush’
RARE
- unexplained bruising or bleeding, which may be due to reduced platelets.
- fever, feeling weak, generally unwell, muscle pain with or without swollen glands (serum sickness)
- joint pain
Contact your doctor immediately if your child experiences any of the following side effects:
- signs of infections (such as fever, general weakness, sore throat or mouth and problems in passing urine)
- severe allergic reaction (such as skin rash, itching, swelling of the face, tongue or pharynx, difficulty to swallow or breathe and chest tightness)
- signs of kidney problems (such as bloody or cloudy urine, scanty or no urine accompanied with lower back pain)
- inflammation of the colon (colitis) with bloody diarrhea
- severe skin reactions causing blistering of the skin, mouth, eyes, and genitals
- signs of low RBC count (such as yellow or pale skin, weakness, or breathlessness)
HOW TO MANAGE SIDE EFFECTS
Diarrhea
Make sure that your child drinks plenty to fluids, such as water or fruit juices to keep themselves hydrated. Consuming ORS can also be beneficial. Do not self-treat diarrhea on your own. Consult your doctor if your child experience severe diarrhea with blood stains.
Nausea And Vomiting
Make sure that your child takes PRODROX 125 TABLET with or just after meals. Eating a simple meal can be beneficial. Avoid giving them oil rich or spicy foods. Consult your doctor if nausea worsens in your child.
WARNING & PRECAUTIONS
DRIVING AND USING MACHINES
Use with CautionPRODROX 125 TABLET may make your child feel dizzy. Therefore, do not let your child to ride bicycle on their own or play with heavy objects. Keep them away from playing outdoors as well.
KIDNEY
Consult your doctorPRODROX 125 TABLET is not recommended for use in children who have severe kidney problems. It should be used with caution in those undergoing dialysis. Therefore, consult your doctor for advice.
LIVER
Use with CautionPRODROX 125 TABLET should be used with caution if your child has any liver problems. Therefore, consult your doctor for advice.
ALLERGY
ContraindicatedTalk to your doctor if your child is allergic to Cefadroxil or to any other penicillin antibiotics (Ex. amoxicillin).
OTHERS
Before using PRODROX 125 TABLET in children, inform your doctor if they:
- are going to have any blood test (such as Coombs test) or urine test
- have a history of stomach problems
Use in pediatrics
PRODROX 125 TABLET should be used with caution in infants, children, and adolescents (below 18 years). Therefore, consult your doctor for advice.
INTERACTIONS
A. Drug-Drug interactions
Inform your doctor if your child is taking any of the following medicines such as:
- medicines used for blood thinning (Ex. heparin and warfarin)
- medicines used to treat gout (Ex. probenecid)
- medicines used to lower elevated blood cholesterol levels (Ex. cholestyramine)
- antibiotics used to treat bacterial infection (Ex. erythromycin, sulfamethoxazole/trimethoprim, chloramphenicol, polymyxin B, vancomycin, colistin, gentamicin)
- diuretics (used to increase urine output) Ex. furosemide
Overdosage
If your child accidentally took more PRODROX 125 TABLET consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage might include allergic reaction causing dizziness or breathing difficulties, low blood pressure, abnormal heartbeat, nausea, vomiting, diarrhea, skin eruptions or muscular contractions.
SYNOPSIS
| Drug | : | Cefadroxil |
| Pharmacological Category | : | Cephalosporins |
| Therapeutic Indication | : | Bacterial infections |
| Dosage Forms | : | Tablet, Capsule, Drops, Dispersible tablet, Oral Drops, Syrup, Suspension, Dry Syrup and Dry, Suspension |
MORE INFORMATION
- Keep PRODROX 125 TABLET out of reach of children
- Store PRODROX 125 TABLET at room temperature
- Consume the medicine immediately after dispersion
FAQs ABOUT PRODROX 125 TABLET
Q: What is PRODROX 125 TABLET used for?
A: PRODROX 125 TABLET is an antibiotic. It is used to treat bacterial infections of the throat and upper part of the respiratory tract, skin and soft tissues, and the urinary tract.
Q: When should I take PRODROX 125 TABLET?
A: PRODROX 125 TABLET is taken preferably after meals. If you are confused or doubtful regarding the use of PRODROX 125 TABLET consult your doctor for advice.
Q: What kind of infections that PRODROX 125 TABLET can treat?
A: PRODROX 125 TABLET is an antibiotic. It is used to treat infections caused by bacteria. It kills harmful bacteria by binding to the bacterial cell and by interfering with cell wall synthesis. It can treat bacterial infections of the throat and upper part of the respiratory tract, skin and soft tissues, and the urinary tract.
Q: Who should not take PRODROX 125 TABLET?
A: PRODROX 125 TABLET should not be used if your child is allergic to penicillin antibiotics (such as amoxicillin, ampicillin) or has severe kidney impairment. It should be used with caution in children with liver problems.
Q: Is PRODROX 125 TABLET a steroid?
A: No. PRODROX 125 TABLET is an antibiotic and not a steroid medicine.
Q: Can PRODROX 125 TABLET treat viral infections?
A: No. PRODROX 125 TABLET cannot treat viral infections. It treats only bacterial infections of upper respiratory tract, urinary tract, and skin infections. It acts by killing the susceptible bacteria which are responsible for causing infections, and therefore not effective against any viral infections.
Q: Can PRODROX 125 TABLET cause diarrhea?
A: Yes. PRODROX 125 TABLET may cause diarrhea in some children. Make sure that your child drinks plenty to fluids, such as water or fruit juices to keep themselves hydrated. Consuming ORS can also be beneficial. Do not self-treat diarrhea on your own. Consult your doctor if your child experience severe diarrhea with blood stains.
Q: Can PRODROX 125 TABLET cause fever?
A: PRODROX 125 TABLET may rarely cause a mild fever in some children. However, if your child experiences heavy fever accompanied with general weakness, sore throat or mouth and problems in passing urine consult your doctor immediately.
Q: Can I stop giving PRODROX 125 TABLET to my child once the symptoms subside?
A: No. It is important to take the full course of PRODROX 125 TABLET without any interruption. Therefore, make sure that your child does not miss a dose of PRODROX 125 TABLET, as it may lead to growth of harmful bacteria within their body which cannot be further controlled by PRODROX 125 TABLET.
Q: Will taking a higher dose of PRODROX 125 TABLET be more effective?
A: No. Taking a higher dose of PRODROX 125 TABLET can do more harm rather than being beneficial. Always take the dose prescribed by your physician. Your doctor will decide the suitable dose for your child depending upon their age, body weight and severity of the infection. Taking a high dose of this medicine, may cause growth of harmful bacteria within their body which cannot be further controlled by PRODROX 125 TABLET. It may also cause unwanted side effects like nausea, vomiting, diarrhea, dizziness or breathing difficulties and low blood pressure.
Q: How to take [GBNKEYWORD]?
A: Take PRODROX 125 TABLET as advised by your physician. Disperse the medicine in boiled and cool water immediately before consumption. PRODROX 125 TABLET must be taken with meals to avoid unwanted gastrointestinal side effects. Your doctor will decide the suitable dose and duration of therapy for your child depending upon their age, body weight and severity of infection.
REFERENCES
1. KD. Tripathi. Antimicrobial drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 726.
2. Keith Kleinman MD, in Harriet Lane Handbook. Cefadroxil. ScienceDirect.com. 2021. [Accessed on 14th June 2022] https://www.sciencedirect.com/topics/medicine-and-dentistry/cefadroxil
3. TORRENT PHARMACEUTICALS LTD. DROXYL DT (Cefadroxil 125 and 250 mg Disintegrating Tablet). [Revised in May 2013]. [Accessed on 14th June 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/24.pdf
4. Cipla Ltd. CEFADUR Tablet (Cefadroxil). Ciplamed.com. [Revised in December 2013] [Accessed on 11th May 2022] https://www.ciplamed.com/content/cefadur-tablet
USEFUL DIAGNOSTIC TESTS
- Complete Blood Count
- Peripheral Smear Examination
- Kidney Function Test
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