INTRODUCTION

PREXARON 500MG contains citicoline which is naturally occurring compound and building block of the cell membranes. It improves cerebral function by increasing blood flow to the brain and enhances cerebral metabolism. This medicine is being commonly prescribed for impaired brain function due to ischaemic neurotoxicity.

It works by increasing the brain chemical and decreasing the damage of brain tissues. It is a potent brain-health nutrient and nootropic. It improves cellular communication by increasing the availability of neurotransmitters, including acetylcholine, norepinephrine, and dopamine. The commonly observed adverse effects were rash, insomnia, numbness of paralyzed extremities, nausea and feeling of warmth.

Always take PREXARON 500MG exactly as prescribed by your doctor. Swallow the medicine whole with plenty of water. Do not drive or operate any machinery while taking this medicine, it may make you feel dizziness, vision problems. If you have any kidney, liver or heart related problems, consult your doctor for advice before taking this medicine. The common side effects are headache, low or high blood pressure, nausea, vomiting, blurred vision and gastrointestinal disorders (i.e., stomach pain, diarrhoea).

USES OF PREXARON 500MG

• treat ischaemic neurotoxicity

HOW PREXARON 500MG WORKS

PREXARON 500MG increases choline stores available for other biosynthetic pathways. It appears to decrease glutamate levels in the brain and increase adenosine triphosphate, which in turn offers protection against ischemic neurotoxicity.

DIRECTIONS FOR USE

Always take PREXARON 500MG exactly as prescribed by your doctor. Swallow the medicine whole with plenty of water.

SIDE EFFECTS OF PREXARON 500MG

HOW TO MANAGE SIDE EFFECTS

Nausea and vomiting:

Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Diarrhea:

Drink lot of fluid, such as water or squash, to avoid dehydration. Do not take any other medicine without consulting your doctor.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor, if you are taking:

• meclophenoxate
• Carbidopa, levodopa and entacapone

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT PREXARON 500MG

Is PREXARON 500MG good for the brain?

It is used by the body to produce acetylcholine, an important neurotransmitter essential for brain and nervous system functions including memory, muscle control and mood.

Can PREXARON 500MG be used in pregnant and breastfeeding women?

It is not recommended for use in pregnant and breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

REFERENCES

1. Karsten Overgaard; Journal of stroke and cerebrovascular diseases; Topic: The Effects of Citicoline on Acute Ischemic Stroke: A Review; [Approved on April 2014] https://www.sciencedirect.com/science/article/pii/S1052305714000494

2. K.D.Tripathi, Essentials of medical Pharmacology, Chapter 35 – CNS stimulant and cognition enhancers; Seventh Edition, 2013. Page – 491.

3. Amherst parenterals Inc. Unilab, Inc. Philippines; [Revised on June 2015] [Accessed 30 Oct 2020] https://assets.unilab.com.ph/uploads/Common/Products/Cholinerv/cholinerv.pdf