INTRODUCTION

PRAX 5MG contains Prasugrel which belongs to a group of medicines called antiplatelet agents. Platelets are very small cell particles that circulate in the blood. When a blood vessel is damaged, platelets clump together to help form a blood clot. When clots form in a blood vessel such as artery, they cut off the blood supply to the heart resulting in heart attack (myocardial infarction), stroke or death. Therefore it is essential to stop bleeding.

It is indicated to prevent blood clot in patients with acute coronary syndrome. It is also given along with other medications in patients who has been treated with a procedure to open blocked arteries and have had one or more stents placed in the heart to prevent stent clotting. It reduces the chances of having a further heart attack or stroke due to any one of these cardiovascular events.

Take PRAX 5MG according to the dose and frequency as advised by your doctor. Swallow the medicine whole, do not crush or chew. It can be taken with or without food. It is not recommended for children and adolescents under 18 years of age. Before taking, inform your doctor if you have any bleeding condition, severe liver disease, pregnant or breastfeeding. The common side effect is bleeding like bruising, nose bleeds, and blood in urine.

USES OF PRAX 5MG

• Prevent blood clot in patients with acute coronary syndrome
• Prevent stent clotting in patients undergone procedure to open blocked arteries

HOW PRAX 5MG WORKS

PRAX 5MG stops the aggregation of platelets by blocking a substance called ADP from binding to a receptor (target) on their surface. This stops the platelets becoming ‘sticky’ and reduces the risk of a blood clot formation, thus helping to prevent a heart attack or a stroke.

DIRECTIONS FOR USE

Take PRAX 5MG according to the dose and frequency as advised by your doctor. Swallow the medicine whole, do not crush or chew. It can be taken with or without food.

SIDE EFFECTS OF PRAX 5MG

HOW TO MANAGE SIDE EFFECTS

Skin rash:

Avoid bath in hot water because hot water can irritate the skin. Moisturizers can be used regular basis to soothe and hydrate the affected area.

WARNING & PRECAUTIONS

INTERACTIONS

Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following,

• clopidogrel, warfarin (used to treat blood clot)
• ibuprofen, naproxen, etoricoxib (used to treat pain or fever)
• morphine or other opioids (used to treat severe pain)

SYNOPSIS

MORE INFORMATION

Store at room temperature and keep out of reach of children.

FAQs ABOUT PRAX 5MG

Is PRAX 5MG effective?

Yes, it is effective if used in the correct dose and duration directed by your doctor.

Do have to stop PRAX 5MG before any surgery?

Your doctor will tell whether you need to stop taking before any surgery. Consult your doctor for advice.

How PRAX 5MG is effective?

It reduces the chances of having a further heart attack or stroke due to any one of these cardiovascular events.

REFERENCES

1. KD Tripathi MD. Drugs affecting blood and Blood formation: Drugs Affecting Coagulation, Bleeding and Thrombosis Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page - 631.

2. Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page - 870.

3. Flipiox KA, White HD, Gersh BJ. Antithrombotic Agents: Platelets Inhibitors, Acute Anticoagulants, Fibrinolytic, and Chronic Anticoagulants. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. Page - 350-351.

4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page - 1142-1143.

5. Mylan Hungary. May 16 2018; [Accessed Nov 10 2020] https://www.ema.europa.eu/en/documents/product-information/prasugrel-mylan-epar-product-information_en.pdf

6. STADA, Electronic Medicines Compendium (EMC); [Revised Dec 2018] [Accessed Nov 10, 2020] https://www.medicines.org.uk/emc/files/pil.9988.pdf  

7. Torrent pharmaceuticals LTD, Dec 2018; [Accessed Nov 10, 2020] https://www.torrentian.com/pisheet/Upload/PI_Sheet/1686.pdf

8. Ciplamed, Jun 10 2014; [Revised June 2016] [Accessed Nov 10, 2020] https://www.ciplamed.com/printpdf/23521

USEFUL DIAGNOSTIC TESTS

• Activated Partial Thromboplastin Time
• Complete Blood Count
• Prothrombin Time