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Drug Information

What is Prasugrel used for?

Prasugrel is used for the treatment of acute coronary syndrome and sickle cell disease.

Prasugrel may also be prescribed for other conditions as determined by the doctor.

How does Prasugrel work?

Prasugrel belongs to the class of drugs called platelet inhibitors. The drug acts by weakening the clumping of platelets. Preventing the clot formation in the blood vessel helps to reduce the blood pressure and improves the blood flow.

How to take Prasugrel?

The dosage and the drug form depend on the age, weight and medical condition of an individual. Take Prasugrel as prescribed by your doctor.

Swallow the tablet whole. Do not crush or chew the tablet. Take the drug with or without food. However, taking the drug with food prevents stomach upset.

If you miss a dose of Prasugrel, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

The overdose symptoms of Prasugrel may include:

  • Shortness of breath
  • Blurred vision
  • Trouble walking
  • Blood in your stools or vomit

What are the drugs that interact with Prasugrel?

Drugs that interact with Prasugrel include the following:

  • Bivalirudin
  • Chlorpheniramine
  • Dalteparin
  • Diclofenac
  • Escitalopram
  • Fondaparinux
  • Ibuprofen
  • Misoprostol
  • Naproxen
  • Oxaprozin
  • Oxycodone
  • Piroxicam
  • Tipranavir
  • Warfarin

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Prasugrel?

The following are the most common side effects of Prasugrel:

  • Blurred vision
  • Headache
  • Nervousness
  • Dizziness
  • Pounding in ears
  • Nausea
  • Diarrhoea
  • Skin rash
  • Stomach upset

The following are the severe side effects and you may require immediate medical attention:

  • Coughing up blood
  • Nose bleeds
  • Unusual tiredness
  • Chest discomfort
  • Irregular heartbeat
  • Mouth ulcers
  • Slurred speech
  • Confusion

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while taking Prasugrel?

  • Avoid using the medicine if you are allergic to Prasugrel or similar drugs.
  • Avoid using Prasugrel if you have any history of bleeding disorders.
  • Do not drive or operate heavy machinery if Prasugrel causes severe drowsiness or vision changes.
  • Do not stop using the medication abruptly unless instructed by the doctor. Discontinuing the medication suddenly may cause the illness to return.
  • Do not take non-steroidal anti-inflammatory drugs, such as Ibuprofen while using Prasugrel drug, as it may increase the risk of bleeding.

You are advised not to take Prasugrel if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before taking Prasugrel?

  • Tell your doctor if you have any history of bleeding disorder or liver disease.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • Notify the doctor if you are pregnant or breastfeeding.

Frequently asked questions about Prasugrel  

  1. Is it safe to alter the dose of Prasugrel?
  2. No. Altering the dose of Prasugrel may increase the risk of side effects. Please consult your doctor.

  3. Is it safe to use Prasugrel medicine in geriatric patients?
  4. Avoid using Prasugrel medication in patients above 75 years of age, as it can increase the risk of intracranial bleeding.

  5. How should Prasugrel be stored?
  6. Prasugrel medication should be stored at room temperature, away from heat, light and excess moisture. Keep the medication away from the reach of children.

  7. Is it necessary to discontinue Prasugrel medicine before a heart surgery?
  8. Yes, you must avoid taking Prasugrel medication at least 1 week before undergoing a coronary artery bypass graft (CABG) surgery, as it may increase the risk of bleeding. Please consult your doctor for further information.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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