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INTRODUCTION
PRAX 10MG TABLET contains Prasugrel which belongs to the group of medicines called Antiplatelet agents. It is used to treat and prevent blood clot formation in the body. It can also reduce the risk of heart attack, stroke, angina (chest pain) and other circulatory problems among patients having heart block, stents in the heart or other heart-related complications.
Before taking PRAX 10MG TABLET inform your doctor if you have any liver or kidney problems. It is strictly not recommended for use in patients with severe liver problems or bleeding problems (internal bleeding conditions).
PRAX 10MG TABLET may make you bleed more easily even after minor cuts or injuries, and so be cautions while you perform even minor activities in your day-to-day life that involves risk of cuts or injuries (like shaving, playing, or handling sharp objects).
You must also inform your doctor if you recently met with any accident or have stomach ulcers, or scheduled for any upcoming surgeries as a precaution, as they could make you bleed more.
Inform your doctor before taking PRAX 10MG TABLET if you are pregnant or breastfeeding. The most common side effects of taking PRAX 10MG TABLET are increased bleeding tendency, anemia, skin rashes and low RBC in blood. Consult your doctor if any of these side effect worsens.
USES OF PRAX 10MG TABLET
- Treats and prevents blood clot formation
- Prevents the risk of heart attack, stroke, angina or other circulatory problems
HOW PRAX 10MG TABLET WORKS
PRAX 10MG TABLET is an antiplatelet medication. It prevents the clumping of platelets (a type of blood cells that causes blood clot) within the blood vessels. This reduces the chances of blood clot formation within the blood vessel and improves blood flow within them. As a result, it reduces the risk of heart attack, stroke and angina.
DIRECTIONS FOR USE
Take PRAX 10MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. It can be taken with or without meals.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking PRAX 10MG TABLET without consulting your doctor.
SIDE EFFECTS OF PRAX 10MG TABLET
COMMON
- increased bleeding or bruising (even after minor cuts)
- nasal bleeds
- skin rashes, red bruises on the skin
- bleeding under the skin if you receive any injections
- anemia (low RBC in blood)
UNCOMMON
- bleeding gums
RARE
- low blood platelet count
Stop taking PRAX 10MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- signs of Thrombotic Thrombocytopenic Purpura (TTP, such as fever and bruising under the skin which can be seen as red pinpoint dots on the skin, with or without extreme tiredness, confusion and yellowing of the skin or eyes)
- signs of stroke (sudden numbness or weakness of the arm, leg or face, especially at one side of the body, sudden confusion, difficulty in speaking and walking, sudden dizziness, or severe headache)
- signs of allergic skin reactions (such as skin rash, itching, swelling of the face, mouth, throat and tongue which causes difficulty in breathing or swallowing)
- rectal bleeding, black or blood-stained stools, bloody urine
HOW TO MANAGE SIDE EFFECTS
Skin rashes:
Avoid hot showers at it may further irritate your skin. Use protective clothing while going outdoors. Consult your doctor for a suitable moisturizer. Do not scratch or rub the affected skin areas. Consult your doctor if the symptom did not improve.
WARNING & PRECAUTIONS
PREGNANCY
PRAX 10MG TABLET should be used in pregnant women only if considered necessary by the physician. Therefore, consult your doctor before taking it.
BREASTFEEDING
PRAX 10MG TABLET should be used in breastfeeding women only if considered necessary by the physician. Therefore, consult your doctor before taking it.
DRIVING AND USING MACHINES
PRAX 10MG TABLET is unlikely to affect your ability to drive or operate any machines.
KIDNEY
PRAX 10MG TABLET should be used with caution in patients with kidney diseases. Therefore, consult your doctor before taking it.
LIVER
PRAX 10MG TABLET is not recommended for use in patients with severe liver diseases. It should be used with caution in patients with moderate liver problems. Therefore, consult your doctor before taking it.
ALLERGY
Do not take PRAX 10MG TABLET if you are allergic to Prasugrel.
OTHERS
PRAX 10MG TABLET is not recommended for use if you:
- have any internal bleeding condition (such as bleeding in the gut)
- have ever had a stroke
- have ever had a transient ischaemic attack (a brief period with stroke-like symptoms)
Before taking PRAX 10MG TABLET, inform your doctor if you:
- had any serious injury recently
- have any stomach conditions (Ex. ulcers or polyps) that can increase the risk of GI bleeding
- have a body weight less than 60 kg
- are scheduled for any upcoming surgery (including minor dental surgery) or recently had one
Use in pediatrics:
PRAX 10MG TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
Use in geriatrics:
PRAX 10MG TABLET should be used with caution in elderly patients (aged 75 years or above). Therefore, consult your doctor before taking it.
INTERACTIONS
A. Drug-Drug interactions:
Before taking PRAX 10MG TABLET, inform your doctor if you are taking any of the following medicines such as:
- other medicines used to prevent blood clots in the body (Ex. clopidogrel, warfarin)
- non-steroidal anti-inflammatory drugs (used for pain relief) such as ibuprofen, naproxen, etoricoxib
Overdosage:
If you or anyone else accidentally took more PRAX 10MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose includes excessive bleeding.
SYNOPSIS
| Drug | : | Prasugrel |
| Pharmacological Category | : | Antiplatelet agents |
| Therapeutic Indication | : | Blood clots |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep PRAX 10MG TABLET out of reach of children
- Store PRAX 10MG TABLET in a room temperature
FAQs ABOUT PRAX 10MG TABLET
What is PRAX 10MG TABLET used for?
PRAX 10MG TABLET is an antiplatelet medicine. It is used to treat and prevent blood clot formation in the body. It can also reduce the risk of heart attack, stroke, angina (chest pain) and other circulatory problems among patients having heart block, stents in the heart or other heart-related complications.
What are the side effects of PRAX 10MG TABLET?
The most common side effects of taking PRAX 10MG TABLET are increased bleeding tendency, anemia, skin rashes and low RBC in blood. Consult your doctor if any of these side effect worsens.
Can I stop taking PRAX 10MG TABLET once my symptoms subside?
No. Do not stop taking PRAX 10MG TABLET without consulting your doctor. As blood clot problems is a chronic conditions, long term treatment is necessary to control its symptoms. Therefore, take PRAX 10MG TABLET as advised by your doctor for the stipulated duration. Sudden withdrawal of therapy may cause the symptoms to reappear.
What should I do if I forget to take a dose of PRAX 10MG TABLET?
If you forget to take a dose of PRAX 10MG TABLET, take it as soon as you remember. However, if it is time to take the next dose, skip the missed dose of PRAX 10MG TABLET and take the next one at the regular time. Do not take a double dose of PRAX 10MG TABLET to compensate the missed dose.
Is PRAX 10MG TABLET a blood thinner?
PRAX 10MG TABLET is an antiplatelet medicine. It prevents the clumping of platelets within the blood vessels which therefore, reduces the chances of blood clot formation in the body.
What precautions do I need to follow while taking PRAX 10MG TABLET?
Before taking PRAX 10MG TABLET inform your doctor if you have any liver or kidney problems or bleeding problems. Be cautions while you perform even minor activities in your day-to-day life that involves risk of cuts or injuries (like shaving, playing, or handling sharp objects). Inform your doctor if you recently met with any accident or have stomach ulcers, or scheduled for any upcoming surgeries as a precaution, as they could make you bleed more. Consult your doctor before taking PRAX 10MG TABLET if you are pregnant, planning to become pregnant or are breastfeeding. Regularly visit your doctor for checkups and perform all the necessary lab tests recommended for you.
Can the use of PRAX 10MG TABLET affect the liver?
Yes. PRAX 10MG TABLET may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it is strictly not recommended for use in patients with severe liver diseases. It should be used with caution in patients with moderate liver problems. Therefore, consult your doctor before taking it.
Should I stop using PRAX 10MG TABLET before any surgery?
Yes. PRAX 10MG TABLET is a blood thinner which may make you bleed more easily even after minor cuts or injuries. As surgeries are always associated with increased bleeding tendency, simultaneous use of PRAX 10MG TABLET is not recommended as it may make you bleed more.
Which medicines should I avoid while taking PRAX 10MG TABLET?
While undergoing therapy with PRAX 10MG TABLET, avoid concomitant use of other blood thinning medications (such as warfarin, clopidogrel) and pain relieving medicines without consulting your doctor.
Is PRAX 10MG TABLET safe for use in children?
PRAX 10MG TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
REFERENCES
1. KD Tripathi. Drugs Affecting Coagulation, Bleeding and Thrombosis. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 629 & 631.
2. Miren E. Jauregui, Ogochukwu U. Umejei, and Martin P. Cruz. Prasugrel an Adenosine Diphosphate Receptor Antagonist for the Treatment of Acute Coronary Syndrome. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. August 2009. [Accessed on 26th November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799124/
3. Shinichi Wakabayashi, Noritaka Ariyoshi, Hideki Kitahara, Kenichi Fujii. Efficacy of 2.5-mg Prasugrel in Elderly or Low-Body-Weight Patients. ResearchGate. June 2018. [Accessed on 26th November 2022] https://www.researchgate.net/publication/326051435_Efficacy_of_25-mg_Prasugrel_in_Elderly_or_Low-Body-Weight_Patients
4. STADA Azneimittel AG. Electronic Medicines Compendium (EMC). [Revised in December 2018] [Accessed on 26th November 2022] https://www.medicines.org.uk/emc/files/pil.9987.pdf
5. Eli Lilly and Company. U.S. Food & Drug Administration. [Revised in April 2010] [Accessed on 26th November 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/022307s001lbl.pdf
6. Central Drugs Standard Control Organization. Prasugrel. May 2010. [Accessed on 26th November 2022] https://cdscoonline.gov.in/CDSCO/Drugs
USEFUL DIAGNOSTIC TESTS
- Complete blood count
- Liver function test
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