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INTRODUCTION
PRASITA A CAPSULE is a combination of Aspirin and Prasugrel which belongs to the group of medicines called Antiplatelet agents. It is used to reduce the risk of blood clot formation in the body.
It is typically used among patients who have undergone percutaneous coronary intervention (PCI, a non-surgical procedure used to open clogged blood vessels supplying the heart) or stent implantation in the heart.
It also prevents the recurrence of heart attack, stroke, angina, atherosclerosis and other circulatory problems caused due to blood clots among patients with heart problems and/or problems in blood circulation.
Before taking PRASITA A CAPSULE inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have asthma, hay fever, high blood pressure, dehydration, heavy menstrual periods or if you are scheduled for any surgery (including minor dental surgeries) in the upcoming days as a precaution.
PRASITA A CAPSULE is not recommended for use in patients with ulcers or bleeding from the stomach or intestines. It is also not suitable for use in pregnant or breastfeeding women unless recommended by a physician.
PRASITA A CAPSULE may also make you bleed more easily even after minor cuts or injuries, and so be cautious while you perform even minor activities that involve the risk of cuts or injuries (like shaving, playing, or handling sharp objects). The most common side effects of taking PRASITA A CAPSULE are increased bleeding tendency, anaemia, stomach problems and indigestion. Consult your doctor if they trouble you.
USES OF PRASITA A CAPSULE
- Prevents the risk of blood clot formation in the body
- Prevents heart attack, stroke, angina or blockage of blood vessels (such as atherosclerosis)
- Prevents the recurrence of heart complications in patients who have undergone stent implantation or procedures to unclog blocked blood vessels supplying the heart (such as PCI)
HOW PRASITA A CAPSULE WORKS
PRASITA A CAPSULE is an antiplatelet medication. It prevents the clumping of platelets (a type of blood cell that causes blood clots) within the blood vessels. This reduces the risk of clot or plaque formation within the blood vessels and improves blood flow to all parts of the body.
DIRECTIONS FOR USE
Take PRASITA A CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. It can be taken with or without meals.
Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight and disease condition. Do not stop taking PRASITA A CAPSULE without consulting your doctor.
SIDE EFFECTS OF PRASITA A CAPSULE
COMMON
- indigestion
- increased tendency for bleeding or bruising
- hematoma (bleeding under the skin, at the site of an injection, or into a muscle, causing swelling)
- nose bleeds
- skin rash
- small red bruises on the skin (ecchymoses)
- low haemoglobin or red blood cell count (anaemia)
UNCOMMON
- hives
- runny nose
- breathing difficulty
- sudden bleeding from the eyes or gums
- coughing up blood
RARE
- inflammation of the stomach lining
- nausea and vomiting
- cramps in the lower respiratory tract
- inflammation in the blood vessels
- heavy or prolonged menstrual periods
- low blood platelet count
Stop taking PRASITA A CAPSULE and contact your doctor immediately if you notice any of the following side effects:
- severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat, and tongue causing difficulty in breathing or swallowing)
- severe allergic skin reactions (such as skin rash, itching, skin redness with blisters or peeling of the skin, and swelling in the mouth, which may be associated with high fever and joint pains)
- unusual or prolonged bleeding tendency (such as coughing up blood, blood in urine, or black or blood-stained stools, bleeding in the stomach or bowels, unusual bleeding or bruising under the skin, nasal bleeds, bleeding in the eye, bleeding inside the head, bleeding in the lung or joints)
- excessive bleeding from small cuts or injuries
- signs of stroke (such as sudden numbness or weakness of the arm, leg or face, especially on one side of the body, confusion, difficulty in speaking or understanding others, difficulty in walking, loss of balance, sudden dizziness, severe headache)
HOW TO MANAGE SIDE EFFECTS
Nausea and Vomiting
Take PRASITA A CAPSULE with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.
WARNING & PRECAUTIONS
PREGNANCY
PRASITA A CAPSULE is not recommended for use in pregnant women (especially during the last 3 months of pregnancy) unless advised by the physician. Therefore, consult your doctor before taking it.
BREASTFEEDING
PRASITA A CAPSULE is not recommended for use in breastfeeding women unless advised by the physician. Therefore, consult your doctor before taking it.
DRIVING AND USING MACHINES
PRASITA A CAPSULE does not affect your ability to drive or operate any machines.
ALCOHOL
Avoid consumption of alcohol while taking PRASITA A CAPSULE as it may increase the risk of side effects.
KIDNEY
PRASITA A CAPSULE is not recommended for use in patients with severe kidney problems. It should be used with caution among patients with other kidney problems. Therefore, consult your doctor before taking it.
LIVER
PRASITA A CAPSULE is not recommended for use in patients with severe liver problems. It should be used with caution among patients with other liver problems. Therefore, consult your doctor before taking it.
ALLERGY
Do not take PRASITA A CAPSULE if you are allergic to Aspirin or Prasugrel.
LUNGS
PRASITA A CAPSULE should be used with caution in patients with asthma or any respiratory diseases. Therefore, consult your doctor before taking it.
HEART DISEASE
PRASITA A CAPSULE should be used with caution among patients with heart problems. Therefore, consult your doctor before taking it.
OTHERS
PRASITA A CAPSULE is not recommended for use if you:
- currently have or ever had any ulcers in the stomach or intestines
- currently have or ever had any signs of bleeding from the gut (such as blood vomits or bloody stools)
- are taking any blood thinning medications
- have any blood clotting disorders (such as haemophilia or thrombocytopenia)
- have gout (joint pain)
- ever had a stroke or mini-stroke
Before taking PRASITA A CAPSULE inform your doctor if you:
- have allergic rhinitis (hay fever causing repeated sneezing, watery eyes, itching of the eyes/nose and runny nose)
- have nasal polyps (a non-cancerous growth in the nose)
- have high blood pressure
- are severely dehydrated
- have G6PD deficiency
- have or previously had any problems in the stomach or intestines
- have heavy menstrual periods
- must undergo any surgery/operation in the upcoming days
Use in Paediatrics:
PRASITA A CAPSULE is not recommended for use in children and adolescents aged below 16 years. Therefore, consult your doctor for advice before administration.
Use in Geriatrics:
PRASITA A CAPSULE should be used with caution in elderly patients. Therefore, consult your doctor for advice before taking it.
INTERACTIONS
A. Drug - Drug interactions:
Before taking PRASITA A CAPSULE, inform your doctor if you are taking any of the following medicines such as:
- heparin, warfarin (medicines used for blood thinning)
- medicines used to treat depression (such as isocarboxazid, phenelzine, selegiline, fluoxetine, moclobemide, sertraline)
- methotrexate (a medicine used to treat cancer or rheumatoid arthritis)
- medicine used to suppress the immune system and to prevent graft rejection (such as ciclosporin or tacrolimus)
- oral contraceptives (birth control pills) Ex. mifepristone, drospirenone, Ethinyl estradiol
- digoxin (a medicine used to treat abnormal heart rhythm)
- medicines used to treat fever or pain (such as ibuprofen)
- corticosteroids (medicines used to treat pain and inflammation) such as prednisolone
- medicines used to treat epilepsy (such as phenytoin and sodium valproate)
- medicines used to treat diabetes (such as glibenclamide, glipizide or insulin)
- medicines used to treat hypertension (such as ramipril, captopril)
- diuretics (used to reduce edema by increasing urine output) such as spironolactone and acetazolamide
- metoclopramide (a medicine used to treat nausea and vomiting)
- medicines used to treat gout (such as probenecid and sulfinpyrazone)
- medicines used to neutralize stomach acids (Ex. aluminium hydroxide, magaldrate)
- lithium (a medicine used to treat mental illnesses)
- acetazolamide (a medicine used to treat glaucoma)
- Zafirlukst (a medicine used for asthma)
- medicines used to treat bacterial infections (such as co-trimoxazole)
Overdosage:
If you or anyone else accidentally took an excessive amount of this medicine, consult your doctor or visit the nearby hospital immediately. Symptoms of an overdose might include vomiting, dehydration, ringing in the ears, vertigo, problems in hearing, sweating, flushing of arms, legs or hands with racing pulse, rapid and deep breathing and increased breathing rate.
SYNOPSIS
| Drug | : | Aspirin, Prasugrel |
| Pharmacological Category | : | Salicylates, P2Y12 Receptor Blockers |
| Therapeutic Indication | : | Prevents blood clots |
| Dosage Forms | : | Capsule |
MORE INFORMATION
- Keep PRASITA A CAPSULE out of reach of children
- Store PRASITA A CAPSULE in a room temperature
FAQs ABOUT PRASITA A CAPSULE
What is PRASITA A CAPSULE used for?
PRASITA A CAPSULE is used to reduce the risk of blood clot formation in patients who have undergone surgeries or non-surgical procedures in the heart (such as PCI or stent implantation). This helps in preventing the recurrence of heart attack, stroke, angina, atherosclerosis and other circulatory problems caused due to blood clots among patients with heart problems and/or problems in blood circulation.
What are the side effects of PRASITA A CAPSULE?
The most common side effects of taking PRASITA A CAPSULE are increased bleeding tendency, anaemia, stomach problems and indigestion. Consult your doctor if they trouble you.
Can I stop taking PRASITA A CAPSULE once my symptoms subside?
No. Do not stop taking PRASITA A CAPSULE without consulting your doctor. As blood clot problems are a chronic condition, long-term treatment is necessary to control its symptoms. Therefore, take PRASITA A CAPSULE as advised by your doctor for the stipulated duration. Sudden withdrawal from therapy may cause the symptoms to reappear.
What should I do if I forget to take a dose of PRASITA A CAPSULE?
If you forget to take a dose of PRASITA A CAPSULE, take it as soon as you remember. However, if it is time to take the next dose, skip the missed dose of PRASITA A CAPSULE and take the next one at the regular time. Do not take a double dose of PRASITA A CAPSULE to compensate for the missed dose.
Is PRASITA A CAPSULE a blood thinner?
Yes. PRASITA A CAPSULE is a blood thinner. It prevents the clumping of platelets (a type of blood cell that causes blood clots) within the blood vessels. This reduces the risk of clot or plaque formation within the blood vessels and improves blood flow to all parts of the body.
What precautions do I need to follow while taking PRASITA A CAPSULE?
Before taking PRASITA A CAPSULE inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have asthma, hay fever, high blood pressure, dehydration, heavy menstrual periods or if you are scheduled for any surgery (including minor dental surgeries) in the upcoming days as a precaution. Do not take PRASITA A CAPSULE if you have ulcers/bleeding in the stomach or intestines or if you are pregnant or breastfeeding. Avoid engaging in activities that involve the risk of cuts or injuries (like shaving, playing, or handling sharp objects) as this medicine may make you bleed more.
Can the use of PRASITA A CAPSULE affect the liver?
Yes. PRASITA A CAPSULE may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it is strictly not recommended for use in patients with severe liver diseases. It should be used with caution in patients with other minor liver problems. Therefore, consult your doctor before taking it.
Should I stop using PRASITA A CAPSULE before any surgery?
Yes. PRASITA A CAPSULE is a blood thinner which may make you bleed more easily even after minor cuts or injuries. As surgeries are always associated with increased bleeding tendency, simultaneous use of PRASITA A CAPSULE is not recommended as it may make you bleed more.
REFERENCES
1. KD. Tripathi. NSAIDS and Anti-pyrectics and Analgesics. Drugs affecting coagulation, bleeding and thrombosis. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 195 & 631.
2. Kirk N. Garratt, W. Douglas Weaver, Ronald G. Jenkins, Thomas K. Pow, Laura Mauri, Dean J. Kereiakes, Kenneth J. Winters, Thomas Christen, Dominic J. Allocco and David P. Lee. Prasugrel Plus Aspirin Beyond 12 Months Is Associated With Improved Outcomes After Taxus Liberté Paclitaxel-Eluting Coronary Stent Placement. AHA Journals. Circulation. November 2014. [Accessed on 24th December 2022]. https://www.ahajournals.org/doi/full/10.1161/circulationaha.114.013570
3. Accord. Electronic Medicines Compendium (EMC). [Revised in March 2021] [Accessed on 24th December 2022]. https://www.medicines.org.uk/emc/files/pil.2408.pdf
4. Laboratorios Lesvi, S.L. Medicines Compendium (EMC). [Revised in January 2019] [Accessed on 24th December 2022]. https://www.medicines.org.uk/emc/files/pil.10033.pdf
5. Torrent pharmaceuticals Ltd. PRAX A 75. [Revised in May 2021] [Accessed on 24th December 2022]. https://www.torrentian.com/pisheet/Upload/PI_Sheet/2591.pdf
6. Central Drugs Standard Control Organization. Prasugrel Hydrochloride IP 10 mg (as film-coated tablet) + Aspirin IP (as enteric coated tablets) 75 mg hard gelatine capsule. January 2014. [Accessed on 24th December 2022]. https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadApprovalNewDrugs/dciApprovedfdc.pdf
USEFUL DIAGNOSTIC TESTS
- Activated Partial Thromboplastin Time
- Complete Blood Count
- Prothrombin Time
PRODUCT DETAILS
ALTERNATE BRANDS
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