Availability & Expiry
INTRODUCTION
PRACTIN SYRUP contains cyproheptadine, which belongs to the group of medicines called Antihistamines. It is used in the treatment of allergic conditions such as seasonal and perineal rhinitis, hay fever, skin rashes and allergic conjunctivitis. The medicine is also used as adjuvant therapy for serious allergic reactions.
Perennial rhinitis refers to specific allergens that cause an allergic reaction year-round, for example, pet hair or dander, food allergies, medicines, etc. Whereas seasonal allergies typically occur with weather changes or environmental changes such as pollen, insects, moisture, dryness, fungi, mold, etc.
PRACTIN SYRUP is not recommended for debilitated patients above 65 years of age having renal, hepatic or cardiac conditions, with angle-closure glaucoma, stenosing peptic ulcer, symptomatic prostatic hypertrophy, neck obstruction of the urinary bladder, pyloroduodenal obstruction and the elderly with worsened health conditions.
PRACTIN SYRUP must be used in pregnant women only if recommended by your doctor. It is not recommended for use in breastfeeding mothers. This medicine should be used with caution in adolescents and children above 2 years of age only. Consult your doctor before taking it. The most common side effects include dizziness, drowsiness, a high fever, etc. Contact your doctor if any of the symptoms worsen.
USES OF PRACTIN SYRUP
Treats allergic conditions in adults and children (above 2 years of age) such as:
- seasonal (occurring during a specific season) and perennial rhinitis (occurring year-round)
- vasomotor rhinitis (reoccurring inflammation of the mucous membrane in the nose)
- allergic conjunctivitis (an eye inflammation caused by allergy)
- urticaria (hives) and angioedema (swelling beneath the skin)
- amelioration of allergic reactions to blood or plasma (allergic severe reactions after blood or plasma transfusions)
- cold urticaria (a skin reaction to the cold)
- dermatographias (a condition causing raised red lines after a scratch)
- adjuvant therapy for serious allergic reactions
HOW PRACTIN SYRUP WORKS
PRACTIN SYRUP treats allergic reactions by binding with certain receptors and blocking them from binding with histamine in the body. Histamine is a mediator found in our body that is responsible for causing allergic symptoms (such as inflammation, itching, irritation, etc.) as a response to allergic conditions. Thereby, providing relief from the allergic condition.
DIRECTIONS FOR USE
Take PRACTIN SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose, frequency and duration of the treatment for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF PRACTIN SYRUP
COMMON
- dizziness, drowsiness
- confusion, agitation
- urinary retention
- tachycardia
- facial flushing
- hyperpyrexia (high temperature)
- dry mucous membrane
- dilated pupil
- constipation
- seizures
- athetosis (involuntary movement of limbs)
- hallucination, delirium
- weight gain
- augmentation of appetite
RARE
- hepatotoxicity
Stop taking PRACTIN SYRUP and contact your doctor immediately if you experience any of the following side effects:
- central nervous system: disturbed coordination, restlessness, excitation, nervousness, tremor, irritability, insomnia, paraesthesia (tickling sensation), neuritis (inflammation of the nerve), euphoria (mood swings), hysteria (mental disorder) and faintness
- outer skin layer: rash and swelling, excessive sweating, a rash with a severe itch, photosensitivity
- special senses: acute labyrinthitis (inflammation of the inner ear), blurred vision, double vision, vertigo (spinning sensation) and tinnitus (ringing in the ears)
- cardiovascular: hypotension, palpitation, tachycardia, extrasystoles (additional heartbeat), severe allergic shock
- hematologic: haemolytic anaemia, leukopenia (low white blood cells), agranulocytosis (high risk of infection), thrombocytopenia (low platelets in the blood)
- digestive system: cholestasis (type of liver disease), liver failure, hepatitis (inflammation of the liver), liver function abnormality, dryness of mouth, epigastric distress (pain on the upper stomach), anorexia (eating disorder), nausea, vomiting, diarrhoea, constipation, jaundice
- genitourinary: urinary frequency, difficult urination, menses
- respiratory: dryness of nose and throat, thickening of bronchial secretions, tightness of chest and wheezing
HOW TO MANAGE SIDE EFFECTS
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Consult your doctor if the symptom does not improve.
Constipation:
Eat plenty of fiber-rich foods such as fresh fruits, vegetables and cereals and drink plenty of water. Exercise more regularly.
WARNING & PRECAUTIONS
PREGNANCY
PRACTIN SYRUP must be used with caution in pregnant women only if recommended by your doctor. Consult your doctor before taking PRACTIN SYRUP.
BREASTFEEDING
PRACTIN SYRUP is not recommended for use by breastfeeding women. Consult your doctor before taking PRACTIN SYRUP.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you feel dizzy or feel that your mental alertness or motor coordination is affected after taking PRACTIN SYRUP.
ALCOHOL
Avoid consumption of alcohol while taking PRACTIN SYRUP because it causes an additive effect, making you feel dizzy or drowsy.
KIDNEY
PRACTIN SYRUP should be taken with caution in patients with severe kidney disease. Consult your doctor before taking PRACTIN SYRUP.
LIVER
There is no adequate information on the use of PRACTIN SYRUP in patients with liver problems. Consult a doctor for advice before taking PRACTIN SYRUP.
ALLERGY
Do not take PRACTIN SYRUP if you are allergic to cyproheptadine.
LUNGS
PRACTIN SYRUP should be taken with caution in patients with a history of bronchial asthma. Consult your doctor before taking PRACTIN SYRUP.
HEART DISEASE
PRACTIN SYRUP should be taken with caution in patients with cardiovascular disease and hypertension. Consult your doctor before taking PRACTIN SYRUP.
OTHERS
PRACTIN SYRUP is not recommended for use if you are suffering from:
- angle-closure glaucoma
- peptic ulcer
- prostatic hypertrophy or bladder neck obstruction (enlargement of the prostate gland)
- intestinal obstruction (pyloroduodenal)
Before taking PRACTIN SYRUP, inform your doctor if you are suffering from:
- increased intraocular pressure (eye pressure)
- hyperthyroidism
Use in paediatrics:
PRACTIN SYRUP should be used with caution in children above 2 years of age and adolescents (under 18 years of age). Consult your doctor before taking PRACTIN SYRUP.
Use in geriatrics:
PRACTIN SYRUP is not recommended in debilitated elderly patients aged over 60 years and above with decreased hepatic, renal or cardiac function. PRACTIN SYRUP is not recommended for use in debilitated elderly patients aged over 60 years and above with decreased hepatic, renal or cardiac function. It should be used with caution only if recommended by your doctor.
INTERACTIONS
A. Drug-Drug interactions:
Before taking PRACTIN SYRUP inform your doctor if you are taking any of the following medicine:
- medicines used to treat depression such as MAO inhibitors (Mono Amine Oxidase inhibitors) (Ex. selegiline)
- other depressants such as CNS depressants (Ex. barbiturates)
- medicine used as sedatives (Ex. diazepam)
- medicines used as hypnotics (Ex. zopiclone)
- medicines used as tranquillizers to treat mental disturbances (Ex. alprazolam)
- anti-anxiety medicine used to treat anxiety (Ex. clonazepam)
Overdosage:
If you or anyone else has accidentally taken too much of PRACTIN SYRUP, consult your doctor immediately or visit the nearby hospital. In children, it could cause diminished mental alertness and sometimes cause excitation. Whereas in adults, it could cause symptoms such as dry mouth, fixed dilated pupils, flushing and gastrointestinal symptoms.
SYNOPSIS
| Drug | : | Cyproheptadine |
| Pharmacological Category | : | Antihistamines |
| Therapeutic Indication | : | treats symptoms associated with allergic conditions |
| Dosage Forms | : | Tablets, capsules, syrup, drops |
MORE INFORMATION
- Keep out of reach from children
- Store at room temperature
FAQs ABOUT PRACTIN SYRUP
Does PRACTIN SYRUP make you gain weight?
Yes, though PRACTIN SYRUP is an antihistamine, it is also used to stimulate the appetite and promote weight gain. On the contrary, it has a negative effect on an average adult as it can cause obesity due to the rapid weight gain in the person after taking it. Consult your doctor before taking PRACTIN SYRUP.
Can PRACTIN SYRUP be used for insect bites?
Yes, PRACTIN SYRUP can be used to treat allergic reactions caused by insect bites. Inflammation and irritation caused by the insect bite are restricted by PRACTIN SYRUP, causing relief from symptoms. Consult a doctor before taking PRACTIN SYRUP.
Can I take PRACTIN SYRUP with anti-depressants?
No, PRACTIN SYRUP is not recommended for use with an anti-depressant (Ex. Sertraline, citalopram), as co-administration of these two medicines may increase the risk of having an additive effect on the medicine and can cause unnecessary complications. Consult a doctor for advice before taking PRACTIN SYRUP.
Does PRACTIN SYRUP make you feel sleepy?
Yes, PRACTIN SYRUP has a sedative property that may make you feel sleepy or drowsy. Avoid driving or using heavy machinery while taking PRACTIN SYRUP.
How long should I take PRACTIN SYRUP?
PRACTIN SYRUP should be taken for as long as your doctor has prescribed it. However, consult your doctor immediately if you experience any of the side effects and they persist or worsen with rash, fever or weight gain.
When should I avoid it before taking PRACTIN SYRUP?
Avoid taking PRACTIN SYRUP if you are suffering from bronchial asthma, glaucoma, enlarged prostate, urinary problems or stomach ulcers. Inform your doctor about your medical condition before starting PRACTIN SYRUP therapy.
Does PRACTIN SYRUP cause dry mouth?
Yes, PRACTIN SYRUP can cause dry mouth. If you experience mouth dryness or feel excessively thirsty, increase your fluid intake, rinse your mouth with water frequently and apply lip balm if you feel your lips dry or chapped out.
REFERENCES
1. K D Tripathi. Antiemetics. Essentials of Medical Pharmacology. 8th edition. Page - 174.
2. Bertrand, Valérie et al. Safety of Cyproheptadine, an Orexigenic Drug. Analysis of the French National Pharmacovigilance Data-Base and Systematic Review. National Library of Medicine. (PMC). September 2021. [Accessed on 1st July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525494/
3. Rising Pharmaceuticals Inc. [Revised in December 2021] [Accessed on 1st July 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e2bf4d46-6585-41d9-868c-98603b165d5b
4. Carilion Materials Management [Revised in August 2011] [Accessed on 1st July 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=949743a7-f922-4248-aa28-818236c80a67
5. Quagen Pharmaceuticals LLC. [Revised in July 2019] [Accessed on 1st July 2022] https://www.quagenpharma.com/uploads/ae943ebb-1b16-4c68-a6b3-ed0083407bcd.pdf
6. InvaTech Pharma Solutions LLC. Safety Data Sheet. [Accessed on 1st July 2022] https://imgcdn.mckesson.com/CumulusWeb/Click_and_learn/SDS_9QUAGN_CYPROHEPTADINE_HCL_SYRP_2MG_5ML.pdf
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