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INTRODUCTION
PNEUMOVAX 23 INJECTION contains Pneumococcal Polysaccharide Serotypes (1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F, and 33F). It is used to prevent the diseases caused by specific streptococcus pneumoniae serotypes in adults (above 50 years) and other individuals (above 2 years) who are at increased risk for pneumococcal disease.
Pneumococcal disease is an infection caused by bacteria, namely Streptococcus pneumoniae or pneumococcus, in the ear, sinuses, lungs, membranes covering the brain, or bloodstream. It is characterised by symptoms such as fever, cough, shortness of breath, chest pain, stiff neck, confusion, headache, chills, ear pain, sleeplessness, and irritability.
PNEUMOVAX 23 INJECTION is not recommended for use if you are allergic to pneumococcal polysaccharide serotypes. It should be used with caution in patients with lung diseases (such as chronic pulmonary disease or compromised lung function), chronic liver disease, chronic kidney diseases, heart diseases (coronary vascular disease, congestive heart failure), or compromised cardiovascular (heart and vessel) function.
PNEUMOVAX 23 INJECTION should be used with caution in pregnant and breastfeeding women. It is not recommended for use in children (below 2 years). PNEUMOVAX 23 INJECTION should be used with caution in elderly patients (aged above 65 years). Consult your doctor before receiving it.
The common side effects associated with the use of PNEUMOVAX 23 INJECTION are headache, weakness, muscle pain, discoloration of the skin due to bleeding beneath the skin, itching, chills, and fever. Contact your doctor or a nearby hospital if any of the conditions worsens or persists.
USES OF PNEUMOVAX 23 INJECTION
- Prevent the diseases caused by specific streptococcus pneumoniae serotypes in adults (above 50 years) and other individuals (above 2 years) who are at increased risk for pneumococcal disease
HOW PNEUMOVAX 23 INJECTION WORKS
PNEUMOVAX 23 INJECTION helps to prevent diseases caused by specific streptococcus pneumoniae serotypes where Pneumococcal Polysaccharide Vaccine stimulates the production of certain neutralizing antibodies that bind to the virus and prevent it from infecting cells thus providing protection from the infection to be caused by specific streptococcus pneumoniae serotypes in future.
DIRECTIONS FOR USE
PNEUMOVAX 23 INJECTION will be given to you only by a doctor or a nurse under the skin as a subcutaneous injection or into a muscle as an intramuscular injection in the deltoid muscle or lateral mid-thigh. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF PNEUMOVAX 23 INJECTION
COMMON
- reaction at the site of injection such as pain, soreness, tenderness, swelling, induration, or redness
- headache
- weakness
- muscle pain
- discolouration of the skin due to bleeding beneath the skin
- itching
- chills
- fever
- diarrhoea
- indigestion
- nausea
- back pain
- neck pain
- upper respiratory infection such as common cold, sore throat
- throat infection
Stop receiving PNEUMOVAX 23 INJECTION and contact your doctor if you experience any of the following side effects:
- angina pectoris (chest pain which is a symptom of underlying heart disease)
- heart failure (sudden loss of heart function)
- chest pain
- ulcerative colitis (inflammation of the intestine with ulcers)
- depression
- headache
- tremors
- stiffness
- sweating
- cerebrovascular accident (any event caused by blood clots in the circulatory system)
- lumbar radiculopathy (pain in lower back and hip)
- pancreatitis (inflammation of pancreatic tissue)
- myocardial infarction (impaired blood supply to heart)
HOW TO MANAGE SIDE EFFECTS
Diarrhea
Drink lots of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to treat diarrhoea and consult your doctor if the symptom gets worse.
Nausea And Vomiting
Stick to simple meals. Avoid eating rich or spicy food. Get a lot of rest. Avoid drinking coffee, alcohol, or smoking. Consult your doctor if the symptom gets worse.
Headache
Take rest and plenty of water. Avoid taking alcohol and skipping meals. Do not strain your eyes by watching the screen for a long time. Consult your doctor if the condition persists for a long or gets worsened.
Indigestion
Try to eat more high-fibre foods such as fresh fruit, vegetables, cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate treatments for constipation.
WARNING & PRECAUTIONS
PREGNANCY
Use with CautionPNEUMOVAX 23 INJECTION should be used with caution in pregnant women. Consult your doctor before receiving the medicine.
BREASTFEEDING
Use with CautionPNEUMOVAX 23 INJECTION should be used with caution in breastfeeding women. Consult your doctor before receiving the medicine.
KIDNEY
Use with CautionPNEUMOVAX 23 INJECTION should be used with caution in patients with chronic kidney disease. Consult your doctor before receiving it.
LIVER
Use with CautionPNEUMOVAX 23 INJECTION should be used with caution in patients with chronic liver disease. Consult your doctor before receiving it.
ALLERGY
ContraindicatedPNEUMOVAX 23 INJECTION is not recommended for use if you are allergic to pneumococcal polysaccharide serotypes or any other ingredients of this medicine.
LUNGS
Use with CautionPNEUMOVAX 23 INJECTION should be used with caution in patients with lung diseases such as chronic pulmonary disease or compromised lung function. Consult your doctor before receiving it.
HEART DISEASE
Use with CautionPNEUMOVAX 23 INJECTION should be used with caution in patients with heart diseases (coronary vascular disease, congestive heart failure) or compromised cardiovascular (heart and vessels) function. Consult your doctor before receiving it.
USE IN PEDIATRICS
ContraindicatedPNEUMOVAX 23 INJECTION is not recommended for use in children (below 2 years). Consult your doctor before receiving it.
USE IN GERIATRICS
Use with CautionPNEUMOVAX 23 INJECTION should be used with caution use in elderly patients (above 65 years). Consult your doctor before receiving it.
OTHERS
Before receiving PNEUMOVAX 23 INJECTION, inform your doctor if you:
- have moderate or acute severe illness
- have diabetes
- have anatomic asplenia (absence of spleen)
- require antibiotic prophylaxis
- have chronic cerebrospinal fluid (CSF) leakage resulting from congenital lesions, skull fractures, or neurosurgical procedures
INTERACTIONS
A. Drug-Drug Interactions:
Before receiving PNEUMOVAX 23 INJECTION, inform your doctor, if you are taking/ receiving any of the following medicines or vaccines:
- vaccines used to prevent shingles
Overdosage:
PNEUMOVAX 23 INJECTION will be given to you only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. However, if you experience any unusual symptoms, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Pneumococcal Polysaccharide Vaccine (PPV) |
| Pharmacological Category | : | Vaccine |
| Therapeutic Indication | : | Prevent the diseases caused by specific Streptococcus Pneumoniae Serotypes |
| Dosage Forms | : | Injection |
MORE INFORMATION
- Keep the medicine out of reach of children
- Store PNEUMOVAX 23 INJECTION at room temperature
FAQs ABOUT PNEUMOVAX 23 INJECTION
Q: What is PNEUMOVAX 23 INJECTION used for?
A: PNEUMOVAX 23 INJECTION is used to prevent the diseases caused by specific Streptococcus pneumoniae serotypes in adults (over 50 years of age) and other individuals (over 2 years of age) who are at increased risk for pneumococcal disease. Consult your doctor before receiving PNEUMOVAX 23 INJECTION.
Q: Is PNEUMOVAX 23 INJECTION safe to use in lung patients?
A: PNEUMOVAX 23 INJECTION should be used with caution in patients with lung diseases such as chronic pulmonary disease or compromised lung function. Consult your doctor before receiving PNEUMOVAX 23 INJECTION.
Q: What side effects are seen with PNEUMOVAX 23 INJECTION?
A: The common side effects associated with the use of PNEUMOVAX 23 INJECTION are headache, weakness, muscle pain, discolouration of the skin due to bleeding beneath the skin, itching, chills, and fever. Contact your doctor or a nearby hospital if any of the conditions worsen or persist.
Q: Who should avoid receiving PNEUMOVAX 23 INJECTION?
A: PNEUMOVAX 23 INJECTION is not recommended for use if you are allergic to pneumococcal polysaccharide serotypes. It is not recommended for use in children (aged below 2 years). Consult your doctor before receiving PNEUMOVAX 23 INJECTION.
Q: Is PNEUMOVAX 23 INJECTION safe to use in children and elderly patients?
A: PNEUMOVAX 23 INJECTION is not recommended for use in children (below 2 years). It should be used with caution in elderly patients (aged above 65 years). Consult your doctor before receiving PNEUMOVAX 23 INJECTION.
Q: How does PNEUMOVAX 23 INJECTION work?
A: PNEUMOVAX 23 INJECTION helps to prevent diseases caused by specific streptococcus pneumoniae serotypes. The pneumococcal polysaccharide vaccine stimulates the production of certain neutralising antibodies that bind to the virus and prevent it from infecting cells, thus providing protection from the infection that may be caused by specific streptococcus pneumoniae serotypes in the future.
Q: What is the method of receiving PNEUMOVAX 23 INJECTION?
A: PNEUMOVAX 23 INJECTION will be given to you only by a doctor or a nurse under the skin as a subcutaneous injection or into a muscle as an intramuscular injection in the deltoid muscle or lateral mid-thigh. Your doctor will determine the correct dose and duration for you depending upon your age, body weight, and disease condition.
Q: Is PNEUMOVAX 23 INJECTION safe to use in liver patients?
A: PNEUMOVAX 23 INJECTION should be used with caution in patients with chronic liver disease (liver diseases that have been prevailing in the body for a long time and are worsening with time). Consult your doctor before receiving PNEUMOVAX 23 INJECTION.
Q: Is PNEUMOVAX 23 INJECTION safe to use in kidney patients?
A: PNEUMOVAX 23 INJECTION should be used with caution in patients with chronic kidney disease (kidney diseases that have been prevailing in the body for a long time and are worsening with time). Consult your doctor before receiving PNEUMOVAX 23 INJECTION.
Q: Is PNEUMOVAX 23 INJECTION safe to use in heart patients?
A: PNEUMOVAX 23 INJECTION should be used with caution in patients with heart diseases (coronary vascular disease, congestive heart failure) or compromised cardiovascular (heart and vessel) function. Consult your doctor before receiving PNEUMOVAX 23 INJECTION.
REFERENCES
1. J. Larry Jameson, A. S. Fauci, D. L. Kasper, S. L. Hauser, D. L. Longo, J. Loscalzo. Pneumococcal Infections. Harrison’s Principles of Internal Medicine. Twentieth Edition. 2018. Page – 1070.
2. Stefaan J. Vandecasteele, Sara Ombelet, Sophie Blumental, Willy E. Peetermans. The ABC of pneumococcal infections and vaccination in patients with chronic kidney disease. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. May 2015. [Assessed 18th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440476/
3. Suvi Harmala, Constantinos Parisinos, Laura Shallcross, Alastair O’Brien, Andrew Hayward. Effectiveness of pneumococcal and influenza vaccines to prevent serious health complications in adults with chronic liver disease: a protocol for a systematic review. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. March 2018. [Assessed 18th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857657/
4. Merck & Co. Inc. PNEUMOVAX® 23. [Revised in April 2021] [Assessed 18th August 2022] https://www.fda.gov/media/80547/download
USEFUL DIAGNOSTIC TESTS
- Blood Test
- Urine Test
PRODUCT DETAILS
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