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INTRODUCTION
PIRFETAB 200MG contain pirfenidone which belongs to a group of medicine called pyridones. It is used to treat mild to moderate Idiopathic Pulmonary Fibrosis in adults. Idiopathic Pulmonary Fibrosis is a condition where the tissues in the lungs become swollen and scarred which leads to breathing difficulty. This medicine helps to reduce scarring and swelling in the lungs, and helps you breathe better.
PIRFETAB 200MG makes your skin sun sensitive. So, wear protective clothing or apply sunscreen while in direct contact with sun. The most common side effects are difficulty sleeping, headache, dizziness, tiredness, loss of appetite, infections of the throat, weight loss. This medicine is strictly not recommended for use in children and adolescents under the age of 18 years.
Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.
USES OF PIRFETAB 200MG
- Treat mild to moderate Idiopathic Pulmonary Fibrosis (IPF)
HOW PIRFETAB 200MG WORKS
PIRFETAB 200MG works by reducing fibrosis (scarring) and swelling in the lungs. This makes breathing easier.
DIRECTIONS FOR USE
Always take PIRFETAB 200MG exactly as your doctor has told you. This medicine must be taken with or without food. Try to take this medicine at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine.
SIDE EFFECTS OF PIRFETAB 200MG
SERIOUS
- swelling of the face, lips and/or tongue, itching, hives, difficulty breathing or wheezing, or feeling faint(angioedema)
- yellowing of the eyes or skin or dark urine, skin itching (signs of abnormal liver function)
COMMON
- skin reactions after going out in the sun or using sunlamps
- nausea
- tiredness
- diarrhoea
- indigestion or stomach upset
- loss of appetite
- headache
- infections of the throat or the airways going into the lungs and/or sinusitis
- bladder infections
- weight loss
- difficulty sleeping
- dizziness
- feeling sleepy
- changes in taste
- hot flushes
- shortness of breath
- cough
- increased levels of liver enzymes
- muscle pain, aching joints/joint pains
- chest pain
RARE
- decrease in white blood cells
HOW TO MANAGE SIDE EFFECTS
Nausea:
Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
Diarrhoea:
Drink lot of fluids such as water or squash, to avoid dehydration. Do not take any other medicines without consult to a doctor.
Headache:
Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.
Dizziness:
Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.
Cough:
Drink fluids which helps thin the mucus in your throat. Suck on cough drops or hard candies.
WARNING & PRECAUTIONS
PREGNANCY
PIRFETAB 200MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
BREASTFEEDING
PIRFETAB 200MG should be used with caution in breast feeding women. Consult your doctor before taking this medicine.
DRIVING AND USING MACHINES
Do not drive or operate any machines while taking this medicine as it may cause dizziness or tiredness.
ALCOHOL
Consumption of alcohol is not recommended during treatment with PIRFETAB 200MG.
KIDNEY
PIRFETAB 200MG is not recommended in patients with active kidney diseases. Before taking, discuss the risks and benefits with your doctor.
LIVER
PIRFETAB 200MG is not recommended in patients with active liver diseases. Before taking, discuss the risks and benefits with your doctor.
ALLERGY
Do not take PIRFETAB 200MG if you are allergic (hypersensitive) to pirfenidone or any other ingredients in this medicine.
INTERACTIONS
Talk to your doctor if you are taking,
- antibiotics such as enoxacin, rifampicin, doxycycline, ciprofloxacin (used to treat infections)
- amiodarone, propafenone (used to treat heart disease)
- fluvoxamine (used to treat depression and obsessive-compulsive disorder)
- omeprazole (used to treat conditions such as indigestion, gastroesophageal reflux disease)
SYNOPSIS
| Drug | : | Pirfenidone |
| Pharmacological Category | : | Anti-inflammatory Agent, Antifibrotic Agent |
| Therapeutic Indication | : | Idiopathic Pulmonary Fibrosis |
| Dosage Forms | : | Tablet |
MORE INFORMATION
Store at room temperature and keep out of reach of children.
FAQs ABOUT PIRFETAB 200MG
Is PIRFETAB 200MG a steroid?
No, it is not a steroid.
What are the benefits of PIRFETAB 200MG?
This medicine is used to treat idiopathic pulmonary fibrosis (IPF) in adults. In Idiopathic Pulmonary Fibrosis the tissues of the lungs get scarred and swell with time, which creates problem in breathing. This medicine helps reduce these effects to make you breathe better.
What should I avoid while taking PIRFETAB 200MG?
You should restrict sun exposure, while taking this medicine. Wear sunblock daily and cover your arms, legs, and head to reduce exposure to sunlight. Along with that, avoid smoking as it decreases the effect of this medicine.
REFERENCES
1. George A Margaritopoulos,1 Eirini Vasarmidi,2 and Katerina M Antoniou2. Pirfenidone in the treatment of idiopathic pulmonary fibrosis: an evidence-based review of its place in therapy. US National Library of Medicines, National Institutes of Health. 1 Jul 2016. [Accessed 27 Nov 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936814/
2. Shu-Min Li, Yang Lin, Shan-Shan Liang. Efficacy of pirfenidone for the treatment of pulmonary fibrosis: An updated systematic review protocol of randomized controlled trial. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. Apr 2019. [Accessed 27 Nov 2020] https://pubmed.ncbi.nlm.nih.gov/31027140/
3. Roche Pharma AG; Electronic Medicines Compendium (EMC) [Revised on Nov 2020] [Accessed 27 Nov 2020] https://www.medicines.org.uk/emc/files/pil.7939.pdf
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