PIPZEE 4.5gm Injection

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Available substitute for PIPZEE 4.5gm Injection 26 substitute/s available
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Please note, before you can choose the low cost generic option, please ask your doctor to add the generic drug to your prescription.

Drug Information for PIPZEE 4.5gm Injection

What is Piperacillin + Tazobactam combination used for?

Piperacillin + Tazobactam combination is used for the treatment of pneumonia and bacterial infections of the abdomen.

Piperacillin + Tazobactam combination may also be prescribed for other conditions as determined by the doctor.

How does Piperacillin + Tazobactam combination work?

In Piperacillin + Tazobactam combination, Piperacillin belongs to the class of drugs called penicillin antibiotics. This drug acts by inhibiting the bacterial cell wall synthesis. It binds to the penicillin binding protein and initiates the process of cell lysis. Thus, it helps in inhibiting the growth of the bacteria.

Tazobactam belongs to the class of drugs called antibiotics. This drug acts by inhibiting the action of certain enzymes that are produced by bacteria as a part of defence mechanism.

How to use Piperacillin + Tazobactam combination?

The dosage and the drug form depend on the age, weight and medical condition of an individual.

Piperacillin + Tazobactam combination is available as an injection. Therefore, it should be administered under medical supervision.  

If you miss a dose of Piperacillin + Tazobactam combination, please consult your doctor immediately.

What are the drugs that interact with Piperacillin + Tazobactam combination?

Drugs that interact with Piperacillin + Tazobactam combination include the following:

  • Cholera vaccine
  • Methotrexate
  • Rifabutin
  • Rifampin

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Piperacillin + Tazobactam combination?

The following are the most common side effects of Piperacillin + Tazobactam combination:

  • Diarrhoea
  • Vomiting
  • Fever
  • Constipation
  • Nausea
  • Dyspepsia
  • Abdominal pain
  • Redness at the site of injection
  • Headache
  • Insomnia
  • Pruritus

The following are the severe side effects and you may require immediate medical attention:

  • Watery/bloody diarrhoea
  • Pale-coloured skin
  • Shortness of breath
  • Increased heart rate
  • Unusual bleeding

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while receiving Piperacillin + Tazobactam combination?

  • Avoid using the medicine if you are allergic to Piperacillin + Tazobactam or similar drugs.
  • Keep the medication away from the reach of children.
  • Do not use Piperacillin + Tazobactam combination medicine if the colour of the solution is changed or if it appears to be cloudy.
  • Seek doctor’s advice before taking any other drug or herbal products while using Piperacillin + Tazobactam combination medication.

What should you tell your doctor before receiving Piperacillin + Tazobactam combination?

  • Tell your doctor if you have a history of cystic fibroids.
  • Inform the doctor if you are taking any other drugs such as cephalosporins, OTC medications, herbal products or nutritional supplements.
  • Inform your doctor before using Piperacillin + Tazobactam combination prior to a scheduled surgery.

Frequently Asked Questions about Piperacillin + Tazobactam

  1. Is it safe to alter the dose of Piperacillin + Tazobactam combination medicine?
  2. No. Altering the dose of Piperacillin + Tazobactam combination medication may increase the risk of convulsions or neuromuscular excitability.

  3. Can I use Piperacillin + Tazobactam combination while suffering from kidney disease?
  4. Using Piperacillin + Tazobactam combination medication while suffering from renal impairment may delay the process of recovery. Please consult your doctor.

  5. Do I need to be monitored for any laboratory parameters while on Piperacillin + Tazobactam combination?
  6. Yes, it is advised to monitor complete blood cell count, sodium/potassium levels, liver and kidney function while on Piperacillin + Tazobactam combination.

  7. Can I continue to use birth control pills while using Piperacillin + Tazobactam combination?
  8. No, Piperacillin + Tazobactam combination medicine may decrease the effectiveness of the birth control pills. Please consult your doctor.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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