PIOGLIZONE 30 Tablet 10's

Diabetes Rx required

Best Price* ₹ 76.60 MRP ₹ 95.75
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: PREVEGO HEALTHCARE & RESEARCH PRIVATE LIMITED * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

PIOGLIZONE 30 contains Pioglitazone which belongs to the group of medicines called Antidiabetic agents. It is used to treat type II diabetes mellitus in adults when treatment with other first line oral antidiabetic medicines (such as metformin) and lifestyle changes (diet and exercise) does not result in adequate response.

Type II diabetes mellitus is a chronic disease characterized by abnormally high levels of glucose in the blood. It is caused due to inadequate production of a hormone called insulin (produced by pancreas to metabolize glucose) in the body or due to inadequate sensitivity of body cells to the actions of insulin.

Pioglitazone is a thiazolidinedione. It reduces blood sugar levels by making the body to utilize the circulating insulin (a peptide hormone used for digesting glucose). It also reduces the production of glucose by the liver which eventually decreases blood glucose levels.

Along with the treatment, follow the diet and lifestyle changes advised by your doctor. Avoid smoking and consumption of alcohol while taking PIOGLIZONE 30 as it can aggravate your existing condition.

PIOGLIZONE 30 is not recommended for use in patients with diabetes ketoacidosis (increased ketone bodies in the blood) or bladder cancer. It is also not suitable for use in patients passing bloody urine and in patients having any severe liver or heart problems.

Before taking PIOGLIZONE 30, inform your doctor if you have any eye problems or menstrual problems (polycystic ovary syndrome). PIOGLIZONE 30 should not be used in pregnant or breastfeeding women unless prescribed by the physician.

One of the most common side effects of taking PIOGLIZONE 30 is hypoglycemia (low blood sugar levels) which can be identified by symptoms such as increased hunger, sweating, shakiness, weakness, or an irregular heartbeat. To avoid this, your doctor will periodically monitor your blood sugar levels and adjust the dose of PIOGLIZONE 30 accordingly.

You can also carry a sugary snack (such as biscuits, glucose drinks or sweet candies) along with you as a precaution and have them immediately if you experience any signs of hypoglycemia. Other most common side effects of taking PIOGLIZONE 30 are abnormal vision, headache, dizziness, weight gain, numbness, joint pain, impotence, back pain, shortness of breath, and anaemia. Consult your doctor if any of these side effect worsens.

USES OF PIOGLIZONE 30

  • Treats Type II diabetes mellitus in adults along with diet and exercise

HOW PIOGLIZONE 30 WORKS

PIOGLIZONE 30 effectively controls blood sugar levels. It contains pioglitazone which is PPAR-gamma and PPAR-alpha agonist. Following administration, it activates certain receptors (PPAR-gamma and PPAR-alpha) in the body which are involved in metabolizing glucose. This helps our body to utilize the circulating insulin for digesting blood glucose which eventually leads to decrease in blood sugar levels. Additionally, PIOGLIZONE 30 can also reduce the glucose produced by the liver.

DIRECTIONS FOR USE

Take PIOGLIZONE 30 as advised by your physician. Swallow PIOGLIZONE 30 with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF PIOGLIZONE 30

COMMON

  • hypoglycemia (low blood sugar levels causing dizziness, shakiness, or hunger)
  • headache, dizziness
  • abnormal vision
  • joint pain, back pain, muscle pain
  • impotence
  • shortness of breath, anaemia
  • flatulence
  • respiratory infection, sinus infection, sore throat
  • weight gain
  • numbness

UNCOMMON

  • difficulty in sleeping (insomnia)
  • sugar in urine
  • proteins in urine
  • spinning sensation (vertigo)
  • sweating, tiredness
  • increased appetite

RARE

Stop taking PIOGLIZONE 30 and contact your physician immediately if you experience any of the following side effects:

  • symptoms of heart failure (such as unusual shortness of breath or trouble in breathing, rapid increase in weight or localised swelling (oedema), especially in the ankles or legs, unusual tiredness)
  • signs and symptoms of bladder cancer (such as blood in your urine, pain while urinating or urgent need to pee)
  • increased risk of fractures (especially in the bones of hand, upper arm, or foot in women)
  • blurred vision due to swelling at the back of the eye or worsening of existing blurred vision
  • serious allergic reaction (such as hives, swelling of the face, lips, tongue, or throat causing difficulty in breathing or swallowing)
  • signs of liver problems (such as nausea or vomiting, stomach pain, unusual or unexplained tiredness, loss of appetite, dark urine, yellowing of the skin or the whites of the eyes)

HOW TO MANAGE SIDE EFFECTS

Headache:  

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol. Consult your doctor if your dizziness worsens.

Hypoglycemia:

Have foods rich in sugars such as fruit juices, glucose drinks, candies, honey, or biscuits. Consult your doctor if there is no improvement in your condition.

WARNING & PRECAUTIONS

PREGNANCY

PIOGLIZONE 30 is generally not recommended for use in pregnant women as it is not known whether the medicine can affect the growth of unborn baby. Therefore, consult your doctor for advice before taking it.

BREASTFEEDING

PIOGLIZONE 30 is generally not recommended for use in breastfeeding women as it is not known whether it may pass through the breast milk. Therefore, consult your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or operate any heavy tools or machines if you experience abnormal vision, after taking PIOGLIZONE 30.

ALCOHOL

Avoid consumption of alcohol while taking PIOGLIZONE 30 as it may increase the risks of side effects.

LIVER

PIOGLIZONE 30 is not recommended for use in patients with severe liver diseases. It should be used with caution in patients with other liver problems. Therefore, consult your doctor before taking it.

ALLERGY

Do not take PIOGLIZONE 30 if you are allergic to Pioglitazone.

HEART DISEASE

PIOGLIZONE 30 is not recommended for use in patients with severe heart problems (such as heart failure). It should be used with caution in patients with other heart problems. Therefore, consult your doctor before taking it.

OTHERS

PIOGLIZONE 30 is not recommended for use if you:

  • have diabetic ketoacidosis (increased levels of ketone bodies in the blood)
  • have bladder cancer
  • pass bloody urine

Before taking PIOGLIZONE 30, inform your doctor if you:

  • have fluid retention and swelling
  • have other urinary problems
  • smoke
  • have special type of diabetic eye disease called macular oedema (swelling of the back of the eye with worsening of your vision)
  • have cysts on your ovaries (polycystic ovary syndrome
  • previous had stroke
  • have anemia (low RBC in blood)
  • have any bone problems or at risk of developing bone fractures
  • are a premenopausal woman

Use in pediatrics:

PIOGLIZONE 30 is not recommended for use in children and adolescents (aged below 18 years). Therefore, contact your doctor before taking it.

Use in geriatrics:

PIOGLIZONE 30 should be used with caution in elderly patients (aged 65 years or above). Therefore, contact your doctor before taking it.

INTERACTIONS

A. Drug-Drug Interaction:

Before taking PIOGLIZONE 30, inform your doctor if you are taking any of the following:

  • non-steroidal anti-inflammatory medicines (used for pain relief) such as celecoxib or etoricoxib
  • gemfibrozil (a medicine used to lower blood cholesterol levels)
  • rifampicin (a medicine used to treat tuberculosis)

Overdosage:

If you or anyone else accidentally took more PIOGLIZONE 30, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage might include hypoglycemia which may cause increased hunger, sweating, shakiness, weakness, or an irregular heartbeat.

SYNOPSIS

Drug :   Pioglitazone
Pharmacological Category :  

PPAR-gamma and PPAR-alpha agonists

Therapeutic Indication :  

Type II Diabetes mellitus

Dosage Forms :   Tablet

MORE INFORMATION

  • Keep PIOGLIZONE 30 out of the sight and reach of children
  • Store PIOGLIZONE 30 below 30°C

FAQs ABOUT PIOGLIZONE 30

How PIOGLIZONE 30 works?

PIOGLIZONE 30 reduces blood sugar levels by making the body to utilize the circulating insulin (a peptide hormone used for digesting glucose). It also reduces the production of glucose by the liver which eventually decreases blood glucose levels.

Does PIOGLIZONE 30 cause bone fractures?

Yes. PIOGLIZONE 30 may cause bone fractures in some individuals. Therefore, it is important for you to inform your doctor before taking PIOGLIZONE 30 if you have any bone problems or at risk of developing any bone fractures (such as menopause).

Does PIOGLIZONE 30 cause weight gain?

Yes. PIOGLIZONE 30 may cause weight gain in some individuals. To avoid this, follow a healthy diet and regular physical activity as advised by your physician. However, if you experience any weight gain due to swelling of body parts (such as in face, legs, or hands), consult your doctor immediately.

What are the side effects of taking PIOGLIZONE 30?

The most common side effects of taking PIOGLIZONE 30 are decreased blood sugar (hypoglycaemia), abnormal vision, headache, dizziness, weight gain, numbness, joint pain, impotence, back pain, shortness of breath, anaemia and increased respiratory infections. Consult your doctor if any of these side effect worsens.

How to take PIOGLIZONE 30?

You must take PIOGLIZONE 30 as advised by your physician. Try to take PIOGLIZONE 30 preferably after meals and swallow it with a glass of water. Do not crush or chew the medicine.

Can PIOGLIZONE 30 be taken with insulin?

Co-administration of PIOGLIZONE 30 with insulin is considered risky as they are increased chances of hypoglycemia (decreased blood sugar levels). Consult your doctor before taking PIOGLIZONE 30 along with insulin.

How much PIOGLIZONE 30 should I take?

PIOGLIZONE 30 should be used only under medical supervision. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body condition and severity of the disease condition.

What should I do if I experience low blood sugar after taking PIOGLIZONE 30?

Low blood sugar is a common side effect of taking PIOGLIZONE 30. Try to have sugar rich food items such as fruit juice, glucose tablets or gel, soft drinks, honey, or sugary candy. Wait for some time. If you cannot any improvement in your condition or if your condition worsen, contact your doctor.

Can PIOGLIZONE 30 cause dizziness?

Yes. Dizziness is a common side effect of using PIOGLIZONE 30. In case you experience dizziness, lie down until it passes, then get up slowly and carefully. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, and alcohol. Do not drive or use machinery to avoid accidents. Consult your doctor if you experience dizziness continuously for a long time after taking PIOGLIZONE 30.

REFERENCES

1. K.D. Tripathi. Insulin, oral hypoglycaemic drugs, and glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 277.

2.Cyrus V. Desouza1,2 and Vijay Shivaswamy1,2. Pioglitazone in the Treatment of Type 2 Diabetes: Safety and Efficacy Review. NIH: National Library of Medicine, National center for biotechnology information. PMC. PubMed Central.3 Aug 2010. [Accessed on 21st June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411525/

3. Gerard Laboratories. Electronic Medicines Compendium (EMC). [Revised in August 2020] [Accessed on 21st June 2022] https://www.medicines.org.uk/emc/files/pil.8836.pdf

4. Takeda Pharmaceuticals America, Inc. U.S. Food & Drug Administration. [Revised in July 2011] [Accessed on 21st June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021073s043s044lbl.pdf

USEFUL DIAGNOSTIC TESTS

  • Glucose - Fasting Blood
  • Glucose - Postprandial Blood
  • Glycosylated Hemoglobin

PRODUCT DETAILS

    Country Of Origin
    India
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PIOGLIZONE 30 Tablet 10's

PIOGLIZONE 30 Tablet 10's Mkt: PREVEGO HEALTHCARE & RESEARCH PRIVATE LIMITED

M.R.P.: Rs.95.75
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