PIMIDE 4mg Tablet 10's

Psychosis Rx required
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MRP ₹90.00
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: D D Pharmaceuticals Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

PIMIDE 4MG contains Pimozide which belongs to a group of medicines called neuroleptics. It is indicated for the suppression of motor and phonic tics (an uncontrollable need to repeat certain movements or sounds) in patients with Tourette’s disorder. This medicine works by decreasing abnormal excitement in the brain. Tourette syndrome is a disorder which involves repetitive movements or unwanted sounds (tics) that cannot be easily controlled.  These illnesses may cause confusion, hallucinations, believe things that are not true (delusions) and suspicious (paranoia).

Pimozide is an antipsychotic medicine which has the ability to blockade dopaminergic receptors on neurons in the central nervous system. It suppresses motor and a phonic tic in Tourette’s Disorder is thought to be a function of its dopaminergic blocking activity. The receptor blockade is often accompanied by a series of secondary alterations in central dopamine metabolism and function which may contribute to both pimozide therapeutic and untoward effects.  

Always take PIMIDE 4MG exactly as directed by your doctor. Tell your doctor if you have liver, kidney or heart problems. This medicine is not recommended for use in children and adolescents below 12 years of age.  The common side effects are sleepiness, dizziness, headache, nausea and dry mouth. Avoid grapefruit juice while taking this medicine.

USES OF PIMIDE 4MG

  • Treats motor and phonic tics (an uncontrollable need to repeat certain movements or sounds) in patients with Tourette’s disorder

HOW PIMIDE 4MG WORKS

PIMIDE 4MG works by changing the activity of certain natural substances in the brain. It affects the chemicals that allow communication between nerve cells (neurotransmitters).

DIRECTIONS FOR USE

Always take PIMIDE 4MG exactly as your doctor has told you. Swallow this medicine with a glass of water and do not crush or chew. It must be taken with food.

SIDE EFFECTS OF PIMIDE 4MG

SERIOUS

  • rash, hives or severe irritation of skin
  • neuroleptic malignant syndrome
  • arrhythmia
  • heart flutters and beats unusually fast
  • muscle stiffness, spasm, shaking, trembling or tremors, feeling restless and stiff neck
  • confusion, muscle twitching, fits
  • swelling, pain and redness in the leg

COMMON

  • sweating more than usual
  • urinating at night
  • dizziness
  • sleepiness
  • agitated or restlessness
  • depression
  • difficulty sleeping
  • feeling tired or lacking in energy
  • loss of appetite
  • dry mouth
  • being sick (nausea)
  • constipation
  • headache
  • blurred vision
  • very oily skin
  • erection problems (in men)
  • weight gain

HOW TO MANAGE SIDE EFFECTS

Nausea:

Stick to regular meals and do not eat rich or spicy foods.

Dizziness:

Get up and move around to feel awake, take a nap to take the edge off sleepiness. 

Constipation:

Eat fruits, vegetables whole grains and high-fiber foods.

Dry mouth:

Chew sugar-free gum or candies to stimulate the flow of saliva and limit your caffeine intake. Drink small sips of water regularly.

Headache:

Rest and drink plenty of fluids. Ask your doctor to recommend a painkiller.

WARNING & PRECAUTIONS

PREGNANCY

PIMIDE 4MG should be used with caution during the last three months of pregnancy. Consult your doctor for advice.

BREASTFEEDING

PIMIDE 4MG is not recommended during breastfeeding. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or handle any machines while taking this medicine as it may cause sleepiness.

ALCOHOL

Consumption of alcohol is not recommended while treatment with PIMIDE 4MG as it may cause drowsiness and less alertness.

KIDNEY

PIMIDE 4MG should be used with caution in patients suffering from kidney function impairment or active kidney diseases. Consult your doctor for advice.

LIVER

PIMIDE 4MG should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.

ALLERGY

Tell your doctor if you are allergic (hypersensitive) to Pimozide.

HEART DISEASE

PIMIDE 4MG is not recommended in patients with long QT syndrome (a specific heart rhythm problem), heart attack, severe heart failure and certain irregularities of heart rhythm. Consult your doctor for advice.

OTHERS

Tell your physician, if you have or had:

  • lower than normal levels of minerals (electrolytes)
  • parkinson’s disease
  • depression
  • epilepsy
  • problems with thyroid gland
  • non-cancerous tumour of the adrenal gland (phaeochromocytoma)
  • history of blood clots
  • dementia

INTERACTIONS

Tell your doctor if you are taking,

  • ketoconazole, itraconazole, miconazole, fluconazole (treats fungal infection)
  • erythromycin, clarithromycin, azithromycin, troleandomycin (treats bacterial infection)
  • indinavir, ritonavir, saquinavir (treats viral infection)
  • quinidine, disopyramide, procainamide, amiodarone, sotalol, bretylium (treats heart problems)
  • terfenadine (treats allergies)
  • cisapride (digestive problems)
  • mefloquine, quinine (treats malaria)
  • nefazodone, amitriptyline, maprotiline, sertraline, paroxetine, citalopram, escitalopram (treats depression)
  • chlorpromazine (for mental disorder)
  • tranquillisers (helps you to sleep)
  • strong painkiller for pain
  • medicines for parkinson's disease and epilepsy
  • metoclopramide (treats sickness)
  • calcium channel blockers and diuretics (treats blood pressure)

SYNOPSIS

Drug :   Pimozide
Pharmacological Category :   First Generation (Typical) Antipsychotic
Therapeutic Indication :   Tourette disorder
Dosage Forms :   Tablet

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT PIMIDE 4MG

Can PIMIDE 4MG be used during breastfeeding?

No, it should not be used during breastfeeding. Consult your doctor for advice.

Does PIMIDE 4MG cause nausea?

It may cause nausea in some individuals, if this persists for a long time. Consult your doctor for advice.

Is PIMIDE 4MG safe?

Yes, it is safe if prescribed by your physician. However, tell your doctor if you have any liver, kidney or heart diseases.

REFERENCES

1. KD Tripathi MD. Antipsychotic and antimanic drugs. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 441.

2. Stahl SM, editor. Pimozide. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. Page: 541-545.

3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page: 1122.

4. L Regeur, B Pakkenberg, R Fog, and H Pakkenberg. Clinical features and long-term treatment with pimozide in 65 patients with Gilles de la Tourette's syndrome. July, 1986. [Accessed on May 11, 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1028904/

5. Gate pharmaceuticals. Teva pharmaceuticals. U.S. Food & Drug Administration [Revised on Jan, 2008] [Accessed on May 11, 2021] https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/017473s041lbl.pdf

6. AA pharma INC. [Revised on March 11, 2014] [Accessed on May 11, 2021] https://www.aapharma.ca/downloads/en/PIL/2016/Pimozide-PM.pdf

7. Eumedica s.a. Lusomedicamenta-Sociedade Tecnica Farmaceutica. Electronic Medicines Compendium (EMC); [Revised on Oct, 2016] [Accessed on May 11, 2021] https://www.medicines.org.uk/emc/files/pil.6911.pdf

PRODUCT DETAILS

    Net Qty
    1
    Item Weight
    17.5
    Ingredient
    PIMOZIDE 4 mg
    Hsn Code
    30049099
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