INTRODUCTION
PERKOCIP 250 contains Ciprofloxacin which belongs to a group of medicines called fluoroquinolones. It is used to treat infections of the skin, sinuses, bone, lung, ear, abdomen, kidney, prostate, and bladder (bacterial infections). It may also used in the management of patients with low white blood cell counts (neutropenia) who have a fever that is suspected to be due to a bacterial infection. Take the medicine according to the dose and duration as advised by your doctor.
Ciprofloxacin is a broad spectrum antibiotic which inhibits DNA gyrase and the synthesis of bacterial DNA and acts as bactericidal, notably against gram-negative bacteria.
Always take PERKOCIP 250 exactly as directed by your doctor. Before taking this medicine, tell your doctor if you have or had any kidney, liver or heart impairment, allergies, epilepsy or joint problems. Tell your doctor if you are taking any medications. Pregnant and breastfeeding mothers consult your doctor before taking the medicine. It is not suitable for use in children and adolescents below 18 years of age. It may also be used to treat other specific severe infections in children and adolescents if your doctor considers it necessary. The common side effects are nausea, diarrhoea, vomiting and skin rash. Do not eat or drink any dairy products (such as milk or yoghurt) or drinks with added calcium as well as food containing caffeine.
USES OF PERKOCIP 250
- Treats infections of the skin, sinuses, bone, lung, ear, abdomen, kidney, prostate, and bladder (bacterial infections)
HOW PERKOCIP 250 WORKS
PERKOCIP 250 works against bacteria that cause infections and acts on specific strains of bacteria.
DIRECTIONS FOR USE
Always take PERKOCIP 250 exactly as your doctor has told you. Swallow as a whole with plenty of water and do not crush or chew.
SIDE EFFECTS OF PERKOCIP 250
SERIOUS
- serious allergic reactions Hives
- trouble breathing or swallowing
- swelling of the lips, tongue, face
- throat tightness or hoarseness
- rapid, irregular heartbeat or feeling fainting
- yellowing of your skin or white part of your eyes and dark urine (liver problem)
- sudden chest, stomach, or back pain
- watery diarrhea with bloody stools
COMMON
- nausea
- diarrhea
- vomiting
- dizziness
- abdominal pain
- skin rashes
RARE
- seizures
HOW TO MANAGE SIDE EFFECTS
Dizziness:
Get up and move around to feel awake, take naps and give your eyes a break to avoid fatigue and eat a healthy food to boost energy.
Nausea or vomiting:
Stick to normal routine meals and avoid spicy foods.
Abdominal pain:
Place a warm water bottle on abdomen or soak in a warm bath. Drink plenty of water.
Diarrhoea:
Drink plenty of fluids to avoid dehydration. ORS also can be used to prevent dehydration.
WARNING & PRECAUTIONS
PREGNANCY
It is preferable to avoid the use of PERKOCIP 250 during pregnancy. Your doctor will weigh the benefits and any potential risks before giving it to you. Consult your doctor for advice.
BREASTFEEDING
PERKOCIP 250 is not recommended during breast-feeding as it may excrete in breast milk and harm your baby. Consult your doctor for advice.
DRIVING AND USING MACHINES
Due to its neurological effects, PERKOCIP 250 may affect reaction time. Thus, the ability to drive or handle any heavy machines may be impaired.
KIDNEY
PERKOCIP 250 should be used with caution in patients suffering from kidney diseases, if needed dose will be adjusted accordingly. Consult your doctor for advice.
LIVER
There are limited data available on PERKOCIP 250 and should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.
ALLERGY
Tell your doctor if you are allergic (hypersensitive) to Ciprofloxacin.
HEART DISEASE
PERKOCIP 250 should be used with caution in patients who recently had a heart attack, had heart rhythm problems (arrhythmias) and heart failure. Consult your doctor for advice.
OTHERS
Inform your doctor before taking this medicine, if you have or had,
- epilepsy or other neurological conditions
- history of tendon problems
- diabetes
- myasthenia gravis
- glucose-6-phosphate dehydrogenase (G6PD)
- enlargement or bulge of a large blood vessel
- aortic dissection (tear in the aorta wall)
INTERACTIONS
Tell your doctor if you are taking,
- tizanidine (used for muscle spasticity)
- cyclosporine (used in organ transplantation)
- methotrexate (treats certain types of cancer, psoriasis, rheumatoid arthritis)
- multivitamins that contain iron
- omeprazole, antacids (treats stomach problem)
- sucralfate
- warfarin, acenocoumarol, phenprocoumon or fluindione (used to thin the blood)
- theophylline (treats breathing problems)
- phenytoin (used for epilepsy)
- probenecid (treats gout)
- ropinirole (treats Parkinson’s disease)
- olanzapine, clozapine (treats psychotic disorders)
- metoclopramide (for nausea and vomiting)
- quinidine, hydroquinidine, disopyramide, amiodarone, sotalol, dofetilide, ibutilide (treats heart problems)
- tricyclic antidepressants, some antimicrobials
- zolpidem (for sleep disorders)
- pentoxifylline (used for circulatory disorders)
- caffeine
- duloxetine (used for depression, diabetic nerve damage or incontinence)
- lidocaine (treats heart conditions or anaesthetic use)
- sildenafil (used for erectile dysfunction)
- agomelatine (for depression)
SYNOPSIS
| Drug | : | Ciprofloxacin |
| Pharmacological Category | : | Fluoroquinolone |
| Therapeutic Indication | : | Bacterial infections |
| Dosage Forms | : | Tablet, Injection, Eye/Ear drops, Eye ointment, Cream |
MORE INFORMATION
Store below 20-25°C and keep out of reach of children.
FAQs ABOUT PERKOCIP 250
Is PERKOCIP 250 addictive or habit forming?
It is not addictive or habit forming if used at prescribed dose and duration as advised by your doctor.
Does PERKOCIP 250 cause diarrhoea?
Yes, it may cause diarrhoea in some individuals, consult your doctor immediately if this persists for a long time.
Can I stop taking PERKOCIP 250 when I feel better?
No, do not stop the medicine and complete the full course of treatment even if you feel better.
REFERENCES
1. KD Tripathi MD. Antimicrobial drugs. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013.Page - 710.
2. Petri WA Jr. Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th edition. New York, New York: McGraw-Hill Medical; 2011. Page - 1473-1474.
3. Chambers HF, Deck DH. Sulfonamides, Trimethoprim, & Quinolons. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th edition. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. Page - 819-820.
4. Tony Thai, Blake H. Salisbury; Patrick M. Zito. Ciprofloxacin. July 07, 2021. [Accessed on Sep 14, 2021] https://www.ncbi.nlm.nih.gov/books/NBK535454/
5. Milpharm Limited. APL Swift Services (Malta) Limited. Electronic Medicines Compendium (EMC); [Revised on Nov, 2020] [Accessed on Sep 14, 2021] https://www.medicines.org.uk/emc/files/pil.7258.pdf
6. Torrent pharmaceuticals Ltd. [Revised on Sep, 2016] [Accessed on Sep 14, 2021] https://www.torrentian.com/pisheet/Upload/PI_Sheet/453.pdf
7. Cipla Ltd. [Revised on July 29, 2020] [Accessed on Sep 14, 2021] https://www.ciplamed.com/print-product-pdf/23634
8. Torque Pharmaceuticals. [Accessed on Sep 14, 2021] https://www.torquepharma.com/product-detail.php?id=92&catid=86
9. Enexi Healthcare. Central Pharma (Contract Packing) Limited. Electronic Medicines Compendium (EMC); [Revised on Nov, 2018] [Accessed on Sep 14, 2021] https://www.medicines.org.uk/emc/files/pil.9828.pdf
USEFUL DIAGNOSTIC TESTS
- Complete Blood Count
- Peripheral Smear Examination
PRODUCT DETAILS
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