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Pecef 100mg Tablet 10'S
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INTRODUCTION
PECEF 100MG TABLET contains Cefpodoxime which belongs to the group of medicines called Antibiotics. It is used to treat infections caused by bacteria such as otitis media (inflammation of middle ear leading to pain and fever), tonsilitis (sore throat, difficulty swallowing and tender lymph nodes), chronic bronchitis (inflammation of the airways present in the lungs leading to cough with mucus), community acquired pneumonia (inflammation of lungs leading to congestion), gonorrhoea (sexually transmitted infection in rectum, cervix or vagina), skin structure infections (rashes, swelling, redness, pain, pus and itching), maxillary sinusitis (inflammation around the nasal cavity leading to headache and runny nose) and cystitis (strong, persistent urge to urinate with burning sensation and blood in the urine).
PECEF 100MG TABLET should be avoided if you are allergic to cefpodoxime or to the cephalosporin group of antibiotics (such as cefuroxime, cefixime) or if you had experienced immediate or severe allergic reaction (anaphylaxis) to penicillin or other beta-lactam antibiotics (such as ampicillin). Before taking PECEF 100MG TABLET, inform your doctor if you have or ever had colitis, liver problems and impaired kidney function. Your doctor may monitor your blood count and liver enzymes through blood tests while taking PECEF 100MG TABLET.
PECEF 100MG TABLET should be used with caution in pregnant women unless clearly advised by the doctor and it is not recommended for use in breastfeeding women. PECEF 100MG TABLET is not recommended for use in infants (less than 2 months of age) and it should be used with caution in elderly patients. The most common side effects of taking PECEF 100MG TABLET are diarrhoea, nausea, itching and irritation in the vagina and vulva, abdominal pain and headache. Consult your doctor if any of the symptom worsens.
USES OF PECEF 100MG TABLET
It is used in adults and adolescents to treat the following bacterial infections:
- Acute otitis media
- Pharyngitis and tonsillitis
- Community-acquired pneumonia
- Acute bacterial exacerbations of chronic bronchitis
- Uncomplicated urethral and cervical gonorrhoea
- Rectal gonococcal infections in women
- Uncomplicated skin and skin structure infections
- Acute maxillary sinusitis
- Uncomplicated urinary tract infections (cystitis)
HOW PECEF 100MG TABLET WORKS
PECEF 100MG TABLET prevents infection by stopping or preventing the bacteria from multiplying by inhibiting their cell wall formation, which is essential for the bacteria to survive as it provides protection from the environment. This kind of action that kills bacteria is useful in treating various bacterial infections.
DIRECTIONS FOR USE
Take PECEF 100MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and severity of infection.
SIDE EFFECTS OF PECEF 100MG TABLET
COMMON
- diarrhoea
- nausea
- fungal infection in vagina and vulva (itching and excess discharge)
- abdominal pain
- headache
UNCOMMON
- fungal, bacterial and parasitic infections
- abdominal distention, malaise, fatigue, weakness, fever, chest pain, back pain, chills and generalized pain
- abscess, allergic reaction and facial edema
- localized edema and pain
- congestive heart failure, palpitations, changes in blood pressure
- hematoma (collection of blood outside of blood vessels)
- migraine
- vomiting, gastritis, dry mouth, flatulence, decreased appetite, constipation
- ulcers in mouth, tongue disorders, tooth disorders, increased thirst and toothache
- anemia, dehydration and weight gain
- dizziness, insomnia, somnolence, anxiety, shakiness, nervousness, impaired concentration, confusion, nightmares
- vertigo (head spinning sensation)
- cough, wheezing, breathing difficulty
- skin rash with itching, hair loss and sunburn
- taste alterations, eye irritation, taste loss and ear pain
- urinary tract infections
RARE
- altered liver function tests
- change in blood cell counts (white blood cells and platelet count)
Stop taking PECEF 100MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- severe diarrhoea due to pseudomembranous colitis
- signs of allergic reaction (skin rash, joint pain, swallowing or breathing problems, swelling of your lips, face, throat or tongue)
- signs of stevens-johnson syndrome (blistering or bleeding of the skin around the lips, eyes, mouth, nose, genitals and fever)
- signs of toxic epidermal necrolysis (severe blistering rash where peeling of skin layer exposes the skin along with feeling of being unwell, fever, chills and muscle pain)
- signs of erythema multiforme (skin rash or skin lesions with a pink/red ring and a pale centre which may be itchy, scaly or filled with fluid, especially on the palms or soles of your feet)
- signs of severe anemia type (infections occur more easily than usual, yellowing of the skin, eyes or mouth and feeling tired)
- seizures mainly in patients with impaired kidney function
HOW TO MANAGE SIDE EFFECTS
Nausea:
Take this medicine with or just after meals. Stick to simple meals and avoid eating oil rich or spicy foods. In case of no improvement in the symptom, consult your doctor.
Diarrhea:
Drink lot of fluids such as water and fruit juice to keep yourself hydrated. Do not consume any medicine on your own to treat without consulting your doctor.
Stomach pain:
Try to rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. In case of no improvement in the symptom, consult your doctor.
Decreased appetite:
Eat when you feel hungry. Eat smaller meals frequently than usual. Snack only when you're hungry. Eat a nutritious snack which is rich in calories and protein, such as dried fruit and nuts. Consult your doctor if the symptom does not improve.
WARNING & PRECAUTIONS
PREGNANCY
PECEF 100MG TABLET is generally not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking PECEF 100MG TABLET.
BREASTFEEDING
PECEF 100MG TABLET is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking PECEF 100MG TABLET.
DRIVING AND USING MACHINES
Do not drive or operate machinery if you feel dizzy and confused after taking PECEF 100MG TABLET.
KIDNEY
PECEF 100MG TABLET should be used with caution in patients with impaired kidney function. Consult your doctor before taking PECEF 100MG TABLET.
LIVER
PECEF 100MG TABLET should be used with caution in patients with liver problems. Consult your doctor before taking PECEF 100MG TABLET.
ALLERGY
Do not take PECEF 100MG TABLET if you are allergic to cefpodoxime or to the cephalosporin group of antibiotics (such as cefuroxime, cefixime) or if you had experienced immediate or severe allergic reaction (anaphylaxis) to penicillin or other betalactam antibiotics (such as ampicillin).
OTHERS
Before taking PECEF 100MG TABLET, inform your doctor if you:
- have history of gastrointestinal disease (particularly colitis)
Use in Paediatrics:
PECEF 100MG TABLET is not recommended for use in infants (less than 2 months of age). Consult child’s doctor for advice to effectively treat the infection.
Use in Geriatrics:
PECEF 100MG TABLET should be used with caution in elderly patients. Consult your doctor before taking PECEF 100MG TABLET.
INTERACTIONS
A. Drug - Drug interactions:
Before taking PECEF 100MG TABLET, inform your doctor if you are taking any of the following medicines:
- medicines used to treat indigestion (Ex. aluminium hydroxide, magnesium hydroxide, simethicone, omeprazole)
- medicines for treating gastric ulcers (Ex. ranitidine, cimetidine)
- medicines used to treat high blood pressure or fluid retention (Ex. spironolactone, bumetanide, torsemide)
- other medicines used to treat bacterial infections (Ex. gentamicin, streptomycin)
- probenecid (used to prevent and treat gouty arthritis)
- warfarin (used to prevent and treat blood clots)
- medicines used to prevent pregnancy (Ex. ethinyl estradiol, desogestrel)
Overdosage:
If you or anyone else accidentally takes too much of PECEF 100MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are nausea, diarrhoea, vomiting and abdominal discomfort.
SYNOPSIS
| Drug | : | Cefpodoxime |
| Pharmacological Category | : | Cephalosporins |
| Therapeutic Indication | : | Bacterial infections |
| Dosage Forms | : | Tablet, Capsule, Dispersible Tablet, Dry Syrup, Dry Suspension, Oral Suspension, Syrup, Oral Drops |
MORE INFORMATION
- Keep PECEF 100MG TABLET out of reach of children
- Store at room temperature
FAQs ABOUT PECEF 100MG TABLET
Q: Is PECEF 100MG TABLET a very strong antibiotic?
A: PECEF 100MG TABLET works against a large spectrum of bacteria to treat tonsillitis, pneumonia, bronchitis, infection of ear, skin, urinary tract, throat, etc. It belongs to cephalosporin antibiotics and it is very effective.
Q: Can PECEF 100MG TABLET be used during pregnancy?
A: PECEF 100MG TABLET is generally not recommended for use in pregnant women unless clearly advised by your doctor. Consult your doctor before taking PECEF 100MG TABLET if you are pregnant or planning to get pregnant.
Q: What are the common side effects of PECEF 100MG TABLET?
A: The common side effects associated with the use of PECEF 100MG TABLET are abdominal pain, diarrhoea, nausea, headache and fungal infection in vagina. If any of the symptoms get worse, consult your doctor immediately.
Q: Is PECEF 100MG TABLET safe to use in patients with kidney problems?
A: PECEF 100MG TABLET should be used with caution in patients with impaired kidney function. Your doctor may adjust the dose depending upon kidney function and patients undergoing hemodialysis. Consult your doctor before taking PECEF 100MG TABLET.
Q: How does PECEF 100MG TABLET work?
A: PECEF 100MG TABLET prevents infection by stopping or preventing the bacteria from multiplying by inhibiting their cell wall formation, which is essential for the bacteria to survive as it provides protection from the environment. This kind of action that kills bacteria is useful in treating various bacterial infections.
REFERENCES
1. KD. Tripathi. Antimicrobial Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 688.
2. Fulton, Bret and Caroline M. Perry. Cefpodoxime proxetil. Paediatric drugs. August 2012 [Accessed on 2nd August 2022] https://link.springer.com/article/10.2165/00128072-200103020-00006
3. Krishan Chugh, Shruti Agrawal. Cefpodoxime: pharmacokinetics and therapeutic uses. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. March 2003. [Accessed on 2ndAugust 2022] https://pubmed.ncbi.nlm.nih.gov/12785294/
4.Pharmacia & Upjohn Company. U.S. Food & Drug Administration. [Revised May 2013] [Accessed on 2nd August 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/050674s015,050675s018lbl.pdf
5. Sanofi Winthrop Industrie. Health Products Regulatory Authority (HPRA). [Revised in April 2014] [Accessed on 2nd August 2022] https://www.hpra.ie/img/uploaded/swedocuments/2142572.PA0540_033_002.da66b7b3-0ec5-4acf-9505-0c8e915e29fc.000001Cefodox%20leaflet.140328.pdf
6. Cipla Ltd. Cefoprox Tablets (Cefpodoxime proxetil). Ciplamed. [Revised in October 2018] [Accessed on 2nd August 2022] https://www.ciplamed.com/content/cefoprox-tabletsdtpowder-for-oral-suspension
USEFUL DIAGNOSTIC TESTS
- Complete Blood Count
- Peripheral Smear Examination
- Urine test
AUTHOR DETAILS
Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 07 Jan 2023 | 10:07 AM(IST)
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