INTRODUCTION

PANLIPASE SR 300 CAPSULE contains Pancreatin which belongs to the group of medicines called Gastrointestinal agents. PANLIPASE SR 300 CAPSULE is used to treat exocrine pancreatic enzyme insufficiency (deficient pancreatic enzyme) in affected individuals.

It is also used to treat pancreatitis (swelling of pancreas), flatulence, cystic fibrosis (genetic disorder that affects lungs and digestive system), moderate indigestion in diabetes and irritable bowel syndrome (intestinal disorder). The medicine is also indicated for use as digestive aid, and in pancreas removal.

PANLIPASE SR 300 CAPSULE is not recommended to use in patients allergic to pork, and/any other pig product. Before taking PANLIPASE SR 300 CAPSULE, inform your doctor if you have kidney problems (such as renal impairment), and/or liver problems (such as hepatic impairment).  

PANLIPASE SR 300 CAPSULE should be used with caution during pregnancy and in women planning for pregnancy. It is safe to use in breastfeeding women.

The medicine should be used with caution in children & adolescents (aged below 18 years) and in elderly patients (aged above 65 years) after consulting the doctor.

The most common side effects of taking PANLIPASE SR 300 CAPSULE are stomach pain, bloating, nausea, vomiting, diarrhea, and/or constipation. Consult your doctor if any of these symptoms worsen.

USES OF PANLIPASE SR 300 CAPSULE

• Treats exocrine pancreatic enzyme insufficiency
• Treats pancreatitis, flatulence, cystic fibrosis, moderate indigestion (in patients with diabetes and irritable bowel syndrome)
• Aids in digestion and pancreas removal

HOW PANLIPASE SR 300 CAPSULE WORKS

PANLIPASE SR 300 CAPSULE is a pancreatic enzyme supplement which works by breaking down fats, starch, and proteins into simpler constituents in the body thus resulting in easy absorption and thereby treating pancreatic enzyme deficiency and its associated symptoms in affected individuals.

DIRECTIONS FOR USE

Tablet:

Take PANLIPASE SR 300 CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Capsule, Minimicrospheres:

Take PANLIPASE SR 300 CAPSULE as advised by your physician. Swallow the medicine with a glass of water as a whole or open the capsule and mix the granules (without crushing) in acidic liquid (such as apple/orange/pineapple juice) or soft food (such as apple sauce/yoghurt). Do not crush/chew the medicine and avoid mixing the granules in non-acidic food/liquid (as it may cause irritation in your mouth/alter the effect of the medicine). Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF PANLIPASE SR 300 CAPSULE

HOW TO MANAGE SIDE EFFECTS

Nausea and vomiting:

Take PANLIPASE SR 300 CAPSULE with or just after a meal. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Talk with your doctor if the condition worsens.

Diarrhea:

Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to treat diarrhea. Consult your doctor and inform them if the symptom gets worse.

Constipation:

Try to eat high-fiber foods such as vegetables, cereals, fresh fruit, and drink plenty of water. Involve in regular exercise (going for a daily walk or run) and if this does not help, consult and inform your doctor for receiving alternate treatments for constipation.

WARNING & PRECAUTIONS

PREGNANCY

PANLIPASE SR 300 CAPSULE should be used with caution during pregnancy and in women planning for pregnancy. Consult your doctor before taking PANLIPASE SR 300 CAPSULE.

BREASTFEEDING

PANLIPASE SR 300 CAPSULE is safe to use in breastfeeding women. Consult your doctor before taking the medicine.

DRIVING AND USING MACHINES

PANLIPASE SR 300 CAPSULE is unlikely to affect your ability to drive or operate machines. Consult your doctor before taking PANLIPASE SR 300 CAPSULE.

KIDNEY

PANLIPASE SR 300 CAPSULE should be used with caution in patients with kidney problems such as renal impairment. Consult your doctor before taking the medicine.

LIVER

PANLIPASE SR 300 CAPSULE should be used with caution in patients with liver problems such as hepatic impairment. Consult your doctor before taking the medicine.

ALLERGY

Do not take PANLIPASE SR 300 CAPSULE if you are allergic to pork, any pig product, and/or any other ingredients of this medicine.

INTERACTIONS

A. Drug-Drug interactions:

Before taking PANLIPASE SR 300 CAPSULE, inform your doctor if you are taking, have recently taken, or might take any other medicines.

Overdosage:

If you or anyone else accidentally take too much of PANLIPASE SR 300 CAPSULE, consult your doctor immediately or visit the nearby hospital. The symptoms of overdosage may include hyperuricosuria (condition marked by increased excretion of uric acid in urine) and hyperuricemia (high uric acid level in blood).

SYNOPSIS

MORE INFORMATION

• Keep PANLIPASE SR 300 CAPSULE out of reach of children
• Do not store PANLIPASE SR 300 CAPSULE above 25°C

FAQs ABOUT PANLIPASE SR 300 CAPSULE

What is PANLIPASE SR 300 CAPSULE used for?

PANLIPASE SR 300 CAPSULE is used to treat exocrine pancreatic enzyme insufficiency (deficient pancreatic enzyme) in affected individuals. It is also used to treat pancreatitis (swelling of pancreas), flatulence, cystic fibrosis (genetic disorder that affects lungs and digestive system), moderate indigestion in diabetes and irritable bowel syndrome (intestinal disorder). The medicine is also indicated for use as digestive aid, and in pancreas removal.

How PANLIPASE SR 300 CAPSULE works?

PANLIPASE SR 300 CAPSULE is a pancreatic enzyme supplement which works by breaking down fats, starch, and proteins into simpler constituents in the body thus resulting in easy absorption and thereby treating pancreatic enzyme deficiency and its associated symptoms in affected individuals. 

What are the side effects of PANLIPASE SR 300 CAPSULE?

The most common side effects of taking PANLIPASE SR 300 CAPSULE are stomach pain, bloating, nausea, vomiting, diarrhea, and/or constipation. Consult your doctor if any of these symptoms worsen.

Does PANLIPASE SR 300 CAPSULE cause diarrhea?

Yes, PANLIPASE SR 300 CAPSULE causes diarrhea as it is the commonest side effect associated with the use of PANLIPASE SR 300 CAPSULE. If such side effects are experienced, then try to eat high-fiber foods (such as vegetables, cereals, fresh fruit, and drink plenty of water) and get involved in regular exercise (such as going for a daily walk/ jog). If this does not help, then consult and inform your doctor for receiving alternate treatments for constipation.

What happens if you take more PANLIPASE SR 300 CAPSULE than your required dose?

If you or anyone else accidentally take too much of PANLIPASE SR 300 CAPSULE, consult your doctor immediately or visit the nearby hospital. The symptoms of overdosage may include hyperuricosuria (condition marked by increased excretion of uric acid in urine) and hyperuricemia (high uric acid level in blood).

REFERENCES

1. K.D. Tripathi. Antiemetic, Prokinetic and Digestant Drugs. Seventh edition. 2013. Page – 670.

2. Priyanka Venkatesh, Anup Kasi. Pancrelipase Therapy. NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet].  July 2022.  [Accessed on 18th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK534816/

3. Didier Rémond, Danit R. Shahar, Doreen Gille, Paula Pinto, Josefa Kachal, Marie-Agnès Peyron, Claudia Nunes Dos Santos, Barbara Walther, Alessandra Bordoni, Didier Dupont, Lidia Tomás-Cobos, and Guy Vergères. Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. June 2015. [Accessed on 18th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546438/

4. Abbott Laboratories GmbH. Electronic Medicines Compendium (EMC). [Revised in November 2021] [Accessed 18th July 2022] https://www.medicines.org.uk/emc/files/pil.1167.pdf

5. INNOVATIVE PHARMACEUTICALS PVT LTD. Panzide 300 mg Capsules. [Accessed on 18th July 2022] https://www.innovativepharma.in/product/panzide-300-mg-capsules/

6. Nutraceutical Corporation. Pancreatin Tablets 350 mg. [Accessed on 18th July 2022] https://www.kalvitamins.com/products/pancreatin

7. Daxin Pharma Pvt. Ltd. PANKRIODAX TAB. [Accessed on 18th July 2022] https://daxinpharma.in/product/pankriodax-tab/

8. Hetero Healthcare Limited. PANMATE CAPSULES. [Accessed on 18th July 2022] https://www.heterohealthcare.com/panmate-capsules             

9. NOW Foods. Pancreatin 2000 Capsules. [Accessed on 18th July 2022] https://www.nowfoods.com/products/supplements/pancreatin-2000-capsules

10. Piramal Pharma Solutions. Digeplex-T. [Accessed on 18th July 2022] https://www.digeplex.com/digeplex-as-a-solution/digeplex-range/digeplex-t-tablets/

11. Tidal Laboratories Pvt. Ltd. Enzox Plus. [Accessed on 18th July 2022] https://tidallabs.com/product.htm

12. Western pharmaceutical industries. Dyspa-East. [Accessed on 18th July 2022] https://western-pharmaceutical.com/en/product/dyspa-east/

13. Torrent pharmaceuticals Ltd. ENZAR. [Revised on March 2020] [Accessed on 18th July 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2788.pdf

USEFUL DIAGNOSTIC TESTS

• Blood test
• Stool evaluation test
• Pancreatic Function test

AUTHOR DETAILS

Written By Dr. K .AZEEM HUSSAIN, B.D.S
Last updated on 12 Nov 2022 | 09:14 AM(IST)