INTRODUCTION

PAMASPAS TABLET is a combination of Dicyclomine, Pamabrom and Paracetamol which belong to the groups of medicines called Anticholinergic, Diuretic and Antipyretic/Analgesic respectively. It is used for the treatment of premenstrual syndrome (PMS) (symptoms such as bloating, water weight gain, swelling and the feeling of being full), dysmenorrhea (painful menstruation), spasmodic pain and colic disease. It is also used to treat the pain and cramps that occur in irritable bowel syndrome (IBS).

Avoid drinking alcohol while taking this medication as it may cause side effects. Avoid overheating by avoiding strenuous work or exercise in hot weather and using hot baths as they cause heatstroke due to less sweat. Before taking PAMASPAS TABLET, inform your doctor if you have diarrhoea, ulcerative colitis, hyperthyroidism, hypertension, kidney problems, liver problems, known or suspected prostatic hypertrophy or heart problems.

PAMASPAS TABLET is not recommended for use by pregnant or breastfeeding women. PAMASPAS TABLET is not recommended for use in infants younger than 6 months of age. The most common side effects of this medicine are dry mouth, dizziness, blurred vision, nausea, vomiting, light-headedness, drowsiness, weakness and nervousness. Contact your physician if any of the above symptoms worsen.

USES OF PAMASPAS TABLET

Treats:

• Premenstrual syndrome (PMS) (symptoms such as bloating, water weight gain, swelling and the feeling of being full)
• Dysmenorrhea (painful menstruation)
• Spasmodic pain
• Colic disease

HOW PAMASPAS TABLET WORKS

PAMASPAS TABLET is a combination of Dicyclomine, Pamabrom and Paracetamol. Dicyclomine is an anticholinergic drug that works by relaxing the muscles in the stomach and gut (intestine). It stops sudden muscle contractions (spasms) and relieves cramps, pain, bloating and discomfort. Pamabrom is a diuretic that increases the production of urine to remove excess water from the body and relieve premenstrual symptoms like bloating, water-weight gain, swelling and the feeling of being full. Paracetamol is an antipyretic (fever reducer) and analgesic (pain killer) that works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).

DIRECTIONS FOR USE

Take PAMASPAS TABLET as advised by your physician. Swallow the medicine with enough water. Do not crush or chew the medicine. The correct dose and duration will be decided by your physician for you depending on your age, body weight and disease condition.

SIDE EFFECTS OF PAMASPAS TABLET

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Take this medicine with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods.

Dizziness:

Lie down until the dizziness goes away and then move slowly and carefully. Take more amount of rest and drink more fluids. Consult your physician if your symptom worsens.

Dry Mouth:

Drink water more frequently, do regular mouth rinses and use sugarless candy.

Diarrhea:

Drink lots of fluids, like water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your physician.

WARNING & PRECAUTIONS

PREGNANCY

PAMASPAS TABLET is not recommended for use in pregnant women. Contact your doctor before taking PAMASPAS TABLET.

BREASTFEEDING

PAMASPAS TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking PAMASPAS TABLET.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel sleepiness, dizziness or blurred vision after taking PAMASPAS TABLET.

ALCOHOL

Avoid consumption of alcohol while taking PAMASPAS TABLET as it may lead to unwanted effects.

KIDNEY

PAMASPAS TABLET should be used with caution in patients with known kidney disease. Contact your doctor before taking PAMASPAS TABLET.

LIVER

PAMASPAS TABLET should be used with caution in patients with known liver disease. Contact your doctor before taking PAMASPAS TABLET.

ALLERGY

Do not take PAMASPAS TABLET if you are allergic to Dicyclomine, Pamabrom, Paracetamol or other ingredients of this medicine.

HEART DISEASE

PAMASPAS TABLET should be used with caution in patients with heart diseases like coronary heart disease, congestive heart failure and cardiac tachyarrhythmia. Contact your doctor before taking PAMASPAS TABLET.

INTERACTIONS

A. Drug-Drug interactions:

Inform your physician if you are using:

• medicine used to treat Parkinson's disease (Ex. amantadine)
• medicines used as antiarrhythmics (prevent and treat a heart rhythm that's too fast or irregular) (Ex. quinidine)
• medicine used to treat allergies (Ex. chlorpheniramine)
• medicines used as antipsychotics (Ex. phenothiazines)
• medicines used to treat anxiety, seizures and insomnia (Ex. alprazolam, diazepam)
• medicines used to treat depression (monoamine oxidases (MAO) inhibitors like isocarboxazid and tricyclic antidepressants (Ex. amitriptyline)
• medicines used as narcotic analgesics (Ex. meperidine)
• using nitrates and nitrites
• medicines used as a sympathomimetic (Ex. amphetamine)
• other medicines having an anticholinergic activity (Ex. amantadine)
• medicines used to treat nausea and vomiting (Ex. metoclopramide)

Overdosage:

If you or anyone else accidentally took too much of this medicine, consult your doctor immediately. The symptoms of overdosage may include headache, nausea, vomiting, blurred vision, dilated pupils, hot dry skin, dizziness, dryness of the mouth, difficulty in swallowing and CNS stimulation including convulsion.

SYNOPSIS

MORE INFORMATION

• Keep out of reach from children
• Store PAMASPAS TABLET at a room temperature

FAQs ABOUT PAMASPAS TABLET

Q: What is PAMASPAS TABLET used for?

A: PAMASPAS TABLET is a combination of Dicyclomine, Pamabrom and Paracetamol, which belong to the groups of medicines called anticholinergic, diuretic and antipyretic/analgesia, respectively. It is used for the treatment of premenstrual syndrome (PMS) (symptoms such as bloating, water weight gain, swelling and the feeling of being full), dysmenorrhea (painful menstruation), spasmodic pain and colic disease. It is also used to treat the pain and cramps that occur in irritable bowel syndrome (IBS).

Q: What are the common side effects of PAMASPAS TABLET?

A: The most common side effects of this medicine are dry mouth, dizziness, blurred vision, nausea, vomiting, light-headedness, drowsiness, weakness and nervousness. Contact your physician if any of the symptoms worsen.

Q: What precaution is to be taken before taking PAMASPAS TABLET?

A: Before taking PAMASPAS TABLET, inform your doctor if you have diarrhoea, ulcerative colitis, hyperthyroidism, hypertension, liver problems, known or suspected prostatic hypertrophy or heart problems.

Q: Is PAMASPAS TABLET suitable for infants?

A: PAMASPAS TABLET is not recommended for use in infants younger than 6 months of age. Contact your doctor before taking PAMASPAS TABLET.

Q: Is PAMASPAS TABLET safe to use in patients with heart problems?

A: PAMASPAS TABLET should be used with caution in patients with heart diseases like coronary heart disease, congestive heart failure and cardiac tachyarrhythmia. Contact your doctor before taking PAMASPAS TABLET.

REFERENCES

1. KD Tripathi. Antiemetic, Prokinetic and Digestant Drugs and Antipyretic-Analgesics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 663, 192-209.

2. Sarah Jefferies, Manoj Saxena and Paul Young. Paracetamol in critical illness: A review. The Australasian Academy of Critical Care Medicine. March 2012. [Accessed on 27th July 2022] https://www.researchgate.net/publication/221690139_Paracetamol_in_critical_illness_A_review

3. Guillermo Di Girolamo, Adriana J Sánchez, Antonio Raul De Los Santos & Claudio D González. Is acetaminophen and its combination with pamabrom, an effective therapeutic option in primary dysmenorrhoea? Journal of Expert Opinion on Pharmacotherapy. 2004. [Accessed on 27th July 2022] https://www.tandfonline.com/doi/abs/10.1517/14656566.5.3.561

4. Kabir Lifesciences. Pamol-D Tablet. [Accessed on 27th July 2022] https://www.kabirlifescience.com/product/pamol-d

5. Pharmed Limited. Pamaspas tablet. [Accessed on 27th July 2022] https://www.pharmedlimited.com/women-health/pamaspas.html

6. Axcan Scandipharm Inc. US Food and Drug Administration. [Revised on July 2006] [Accessed on 27th July 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/007409s040,007961s026,008370s031lbl.pdf

7. Alva-Amco Pharmacal Companies Inc. Dailymed. [Revised on December 2021] [Accessed on 27th July 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ab10451e-ff87-4974-bec4-7ba19c5bbe65

8. Reliable 1 Laboratories LLC. Dailymed. [Revised on October 2021] [Accessed on 27th July 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=25626b46-78f8-7226-e054-00144ff8d46c

AUTHOR DETAILS

Written By Dr. Dhivakaran R, BDS
Last updated on 30 Dec 2022 | 05:35 PM(IST)