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INTRODUCTION
OXANA 2% PREFILLED SYRINGE(PFS) contains Hydroxypropyl Methylcellulose which belongs to the group of medicines called Ophthalmic demulcent. It is used as a surgical aid in ophthalmic procedures involving anterior segment of the eye such as cataract surgery with intraocular lens implantation, keratoplasty or filtering operations for glaucoma.
It is also used to prevent lenticular opacity pre-operatively and used to prevent posterior capsular opacity (PCO) (in patients with post cataract operation).
Do not receive OXANA 2% PREFILLED SYRINGE(PFS) if you are allergic to hydroxypropyl methylcellulose/hypromellose. Before receiving this medicine, inform your doctor if you have liver impairment or renal failure.
OXANA 2% PREFILLED SYRINGE(PFS) should be used with caution in pregnant and breastfeeding women. It should be used with caution in children and elderly patients. Consult your doctor before receiving it.
The common side effects associated with the use of OXANA 2% PREFILLED SYRINGE(PFS) are blurred vision, eye pain and eye irritation. Consult your doctor if any of the side effect worsens.
USES OF OXANA 2% PREFILLED SYRINGE(PFS)
- Used as a surgical aid in ophthalmic procedures involving anterior segment of the eye such as cataract surgery with intraocular lens implantation, keratoplasty or filtering operations for glaucoma
- Prevents lenticular opacity pre-operatively
- Prevents posterior capsular opacity (PCO) (in patients with post cataract operation)
HOW OXANA 2% PREFILLED SYRINGE(PFS) WORKS
OXANA 2% PREFILLED SYRINGE(PFS) helps in aiding ophthalmic procedures where hydroxypropyl methylcellulose is a hydrophilic polymer that works by crosslinking on the eye surface, thereby increasing the tear clearance time and promoting the eye lubrication.
DIRECTIONS FOR USE
OXANA 2% PREFILLED SYRINGE(PFS) will be given to you only by a doctor or a nurse into the anterior chamber of the eye. It is for ophthalmic use only. Enough of this medicine is slowly introduced into the anterior chamber using a cannula. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF OXANA 2% PREFILLED SYRINGE(PFS)
COMMON
- blurred vision
- eye pain
- eye irritation
HOW TO MANAGE SIDE EFFECTS
Eye Irritation Or Itching
Clean the eyelids daily. Give rest to your eyes while using a computer screen by taking breaks. Ensure the computer screen is placed just below eye level. Try using a humidifier in the room to prevent the air getting dry. Avoid spending much time in smoky, dusty, dry, air conditioned or artificially heated places.
WARNING & PRECAUTIONS
PREGNANCY
Use with CautionOXANA 2% PREFILLED SYRINGE(PFS) should be used with caution during pregnancy. Consult your doctor before receiving it.
BREASTFEEDING
Use with CautionOXANA 2% PREFILLED SYRINGE(PFS) should be using with caution in breastfeeding women. Consult your doctor before receiving it.
KIDNEY
Consult your doctorThere is no proper information regarding the use of OXANA 2% PREFILLED SYRINGE(PFS) in patients with renal failure. Consult your doctor before receiving it.
LIVER
Consult your doctorThere is no proper information regarding the use of OXANA 2% PREFILLED SYRINGE(PFS) in patients with liver impairment. Consult your doctor before receiving it.
ALLERGY
ContraindicatedDo not receive OXANA 2% PREFILLED SYRINGE(PFS) if you are allergic to hydroxypropyl methylcellulose/hypromellose or any other ingredients of this medicine.
OTHERS
Use in Paediatrics:
There is no proper information regarding the use of OXANA 2% PREFILLED SYRINGE(PFS) in children. Consult your child’s doctor for advice.
Use in Geriatrics:
OXANA 2% PREFILLED SYRINGE(PFS) should be used with caution in elderly patients. Consult your doctor before receiving it.
INTERACTIONS
A. Drug-Drug Interactions:
Before receiving OXANA 2% PREFILLED SYRINGE(PFS), inform your doctor if you are taking any medicines including prescription, non-prescription, herbals and vitamin supplements.
Overdosage:
OXANA 2% PREFILLED SYRINGE(PFS) will be given to you only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. Overfilling of anterior chamber may increase the pressure inside the eyes.
SYNOPSIS
| Drug | : | Hydroxypropyl Methylcellulose |
| Pharmacological Category | : | Ophthalmic demulcent |
| Therapeutic Indication | : | Surgical aid in ophthalmic procedures |
| Dosage Forms | : | Eye drops, Ophthalmic solution, Solution, Liquid, Eye gel, Gel, Injection, Prefilled syringes |
MORE INFORMATION
- Store at room temperature
FAQs ABOUT OXANA 2% PREFILLED SYRINGE(PFS)
Q: Who should avoid receiving OXANA 2% PREFILLED SYRINGE(PFS)?
A: Do not receive OXANA 2% PREFILLED SYRINGE(PFS) if you are allergic to hydroxypropyl methylcellulose/hypromellose or any other ingredients of this medicine. Consult your doctor before receiving it.
Q: How does OXANA 2% PREFILLED SYRINGE(PFS) work?
A: OXANA 2% PREFILLED SYRINGE(PFS) helps in aiding ophthalmic procedures where hydroxypropyl methylcellulose is a hydrophilic polymer that works by crosslinking on the eye surface, thereby increasing the tear clearance time and promoting the eye lubrication.
Q: What is the method of receiving OXANA 2% PREFILLED SYRINGE(PFS)?
A: OXANA 2% PREFILLED SYRINGE(PFS) will be given to you only by a doctor or a nurse into the anterior chamber of the eye. It is for ophthalmic use only. Enough of this medicine is slowly introduced into the anterior chamber using a cannula. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Q: Is OXANA 2% PREFILLED SYRINGE(PFS) safe to use in pregnant and breastfeeding women?
A: OXANA 2% PREFILLED SYRINGE(PFS) should be used with caution if you are pregnant or breast-feeding. Consult your doctor before receiving such medicine to prevent any harm to mother and/or baby.
Q: What are the common side effects of receiving OXANA 2% PREFILLED SYRINGE(PFS)?
A: The common side effects associated with the use of OXANA 2% PREFILLED SYRINGE(PFS) are blurred vision, eye pain and eye irritation. Consult your doctor if any of the side effect worsens.
REFERENCES
1. J. Larry Jameson, Anthony S. Fauci, Dennis L. Kasper, Stephen L. Hareciever, Dan L. Longo, Joseph Loscalzo. The Spondyloarthritides. Harrison’s Principles of Internal Medicine. Twentieth edition. 2018. Page – 2562.
2. L C Chumbley, A M Morgan, Musallam. Hydroxypropyl methylcellulose in extracapsular cataract surgery with intraocular lens implantation: intraocular pressure and inflammatory response. NIH National Library of Medicine. National Centre for Biotechnology Information. PubMed.gov. 1990. [Accessed on 3rd December 2022] https://pubmed.ncbi.nlm.nih.gov/2323463/
3. Centaur Pharma. Viscotrust vial (Hydroxy propyl methylcellulose). [Accessed on 03rd December 2022] https://www.centaurpharma.com/downloads/Viscotrust2018.pdf
4. Centaur Pharma. Viscotrust-PFS (Hydroxypropyl Methycellulose Ophthalmic Solution). [Accessed on 3rd December 2022] https://www.centaurpharma.com/downloads/Viscotrust.pdf
5. Appasamy Associates. Appavisc Pfs (Hydroxypropyl Methycellulose Ophthalmic Solution). [Accessed on 3rd December 2022] https://www.appasamy.com/pharmaceuticals.php?category=Cataract_Surgical_Products&product=APPAVISC_PFS_2ML,_3ML
USEFUL DIAGNOSTIC TESTS
- Schirmer Test
- Phenol Red Thread Test
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