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INTRODUCTION

OTAX 500 INJECTION contains Cefotaxime which belongs to the group of medicines called Antibiotics. It is used to treat serious bacterial infections such as blood stream (septicemia), bones (osteomyelitis), heart valves (endocarditis), membranes covering the brain (meningitis) and lining of the abdomen (peritonitis), lungs (pneumonia), skin and soft tissue, urinary tract, genitals (including gonorrhea), blood (bacteremia), Lyme disease (borreliosis), an infection primarily caused by tick bites and also to prevent and treat infections following surgical operations.

Before receiving this OTAX 500 INJECTION, inform your doctor if you have liver, kidney problems or high blood pressure. Consult your doctor for advice.

Pregnant and breastfeeding women should consult their doctor before receiving this medicine.

Your doctor will administer the right dose depends on your child’s age, body weight and severity of the infection. Consult your doctor for advice before receiving the medicine.

Treatment with high doses of OTAX 500 INJECTION, particularly in patients with kidney problems, has been known to cause loss of consciousness, abnormal movements and convulsions and brain disease. Consult your doctor before receiving the medicine.

The common side effects of receiving this medicine are nausea, vomiting, stomach pain, diarrhea and injection site pain. Consult your doctor if any of the above symptoms worsens.

USES OF OTAX 500 INJECTION

  • Used to treat patients with serious bacterial infections

HOW OTAX 500 INJECTION WORKS

OTAX 500 INJECTION works by inhibiting the biosynthesis of a protective layer of a bacterial cell wall called peptidoglycan. This leads to interruption of cell wall synthesis, consequently leading to inhibition in cell growth and cell lysis.

DIRECTIONS FOR USE

OTAX 500 INJECTION will be injected intramuscularly (into a muscle) or intravenously (into a vein) by your doctor or nurse. Your doctor will administer the right dose depends on your age, body weight and severity of the infection.

SIDE EFFECTS OF OTAX 500 INJECTION

COMMON

  • nausea, vomiting
  • stomach pain
  • diarrhea
  • sore, pain in muscle (injection site reactions)
  • headache
  • dizziness
  • anemia or other changes in the blood (which can cause sore throat and mouth ulcers or a tendency to bleed or bruise easily)
  • temporary changes in liver function, inflammation of the liver
  • painful joints and thrush
  • swelling around the area of infection or inflammation of the vein
  • blood clot in a vein or irregular heart rhythm

UNCOMMON

  • sudden fever and shivering (Jarisch-Herxheimer reactions)
  • skin rash (nettle rash), itchy skin,skin redness
  • soft stools
  • convulsions
  • cramps
  • drop or elevation of the number of certain blood cells such as eosinophilia, leucopoenia, thrombocytopenia
  • increase in enzymes

RARE

Contact your doctor immediately, if you have experience any of the following side effects:

  • severe allergic reactions symptoms such as rash, itching, fever and, peeling skin, swelling of the face and difficulty breathing
  • inflammation of the inner lining of the colon (colitis) symptoms such as diarrhoea, abdominal cramps or pain, nausea, dehydration, fever or bloody, watery diarrhoea
  • stevens-Johnson syndrome or toxic epidermal necrolysis symptoms such as widespread rash with blisters and peeling skin
  • severe, persistent diarrhoea
  • superinfection

HOW TO MANAGE SIDE EFFECTS

Nausea and Vomiting:

Try to take this medicine with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food.

Stomach pain:

Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Do not self-treat on your own and consult your doctor if the symptom did not improve on its own.

Diarrhoea:

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhoea. Consult your doctor if the symptom did not improve.

Headache:

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on your head if required. Consult your doctor if the symptom did not improve.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.

WARNING & PRECAUTIONS

PREGNANCY

OTAX 500 INJECTION should be used with caution in pregnant women unless considered necessary. Consult your doctor before receiving this medicine.

BREASTFEEDING

OTAX 500 INJECTION is not recommended for use in breast feeding women. Consult your doctor before receiving this medicine.

DRIVING AND USING MACHINES

Do not drive or use any tools or machines while receiving this OTAX 500 INJECTION, it may cause involuntary muscle contractions, dizziness or alertness problems.

KIDNEY

OTAX 500 INJECTION should be used with caution in patients suffering from kidney problems. Consult your doctor before receiving this medicine.

LIVER

OTAX 500 INJECTION should be used with caution in patients suffering from liver problems. Consult your doctor before receiving this medicine.

ALLERGY

Do not receive OTAX 500 INJECTION if you are allergic (hypersensitive) to Cefotaxime or any other ingredients of this medicine.

HEART DISEASE

OTAX 500 INJECTION is not recommended in patients with heart diseases, problems with heartbeat or severe heart failure. Consult your doctor before receiving this medicine.

OTHERS

Before receiving this medicine, inform your doctor if you:

  • are on low salt diet
  • have blood transfusion
  • are a diabetic patient

Use in pediatrics:

Your doctor will administer the right dose depends on your child’s age, body weight and severity of the infection. Consult your doctor before receiving OTAX 500 INJECTION.

Use in geriatrics:

OTAX 500 INJECTION should be used with caution in elderly patients. Consult your doctor before receiving this medicine.

INTERACTIONS

A. Drug - Drug interactions:

Before receiving OTAX 500 INJECTION tell your doctor if you are taking any of the following medicine:

  • mezlocillin, azlocillin, streptomycin, neomycin, gentamicin,kanamycin, amikacin or tobramycin (used to treat bacterial infections)
  • furosemide, etacrynic acid or other strong diuretics (used to get rid of excess water from the body
  • probenecid (used to prevent and treat gout)

Overdosage:

It is unlikely to get an overdose since it is administered by your doctor or nurse. If you experience any unusual reactions, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

Drug :   Cefotaxime
Pharmacological Category :   Cephalosporin
Therapeutic Indication :   Treats serious Bacterial infections
Dosage Forms :   Injection, Dry syrup, Tablet

MORE INFORMATION

  • Keep this medicine out of reach of children
  • Store at a room temperature

FAQs ABOUT OTAX 500 INJECTION

Is OTAX 500 INJECTION same as penicillin?

No, it belongs to third generation class of cephalosporins, it is active against numerous gram-positive and gram-negative bacteria, including several with resistance to other antibiotics such as penicillin.

Is OTAX 500 INJECTION effective?

Yes, it is effective, if used in the dose and duration advised by your doctor. Do not stop taking, if you see improvement on your condition, if you stop using the medicine too early the symptoms may return or worsen.

Can I stop receiving OTAX 500 INJECTION when my symptoms are relieved or when I feel better?

No, do not stop receiving this medicine before completing the full course of treatment. You may start feeling better before the infection is completely cured. But it is important to take this medicine for the full duration advised by the doctor.

How is OTAX 500 INJECTION administered?

OTAX 500 INJECTION is administered under the supervision of a trained healthcare professional or a doctor and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor.

Can the use of OTAX 500 INJECTION cause diarrhoea?

Yes, the use of OTAX 500 INJECTION can cause diarrhoea. It is an antibiotic which works against the harmful bacteria. However, it may also affect the helpful bacteria in your stomach or intestine and causes diarrhoea. If diarrhoea persists for a long time, consult your doctor for advice.

REFERENCES

1. KD. Tripathi.Beta-Lactam Antibiotics. Essentials of medical pharmacology. Seventh edition. 2013. Page –727

2. CP Pharmaceuticals Ltd; Electronic Medicines Compendium (EMC) [Revised on Mar 2017] [Accessed 09 Mar 2022] https://www.medicines.org.uk/emc/files/pil.1508.pdf

3. Demo S.A; Electronic Medicines Compendium (EMC) [Revised on Mar 2020] [Accessed 09 Mar 2022] https://www.medicines.org.uk/emc/files/pil.12713.pdf

4. MRI.CRT. [Accessed 09 Mar 2022] https://mri.cts-mrp.eu/Human/Downloads/DK_H_2158_002_FinalPL.pdf

5. Pub chem. Cefotaxime. [Accessed 09 Mar 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Cefotaxime

USEFUL DIAGNOSTIC TESTS

  • Complete Blood Count
  • Peripheral Smear Examination

AUTHOR DETAILS

Written By Dr. Janet.C, Pharm.D
Last updated on 21 Oct 2022 | 12:21 PM(IST)

PRODUCT DETAILS

    Country Of Origin
    India
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

OTAX 500 Injection 1's

OTAX 500 Injection 1's Mkt: Oscar Remedies Pvt. Ltd

₹ 19.97 MRP ₹ 24.35