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INTRODUCTION
ONDEWAR SYRUP contains Ondansetron which belongs to a group of medicines called Anti-emetics. ONDEWAR SYRUP is used to prevent nausea and vomiting in children caused by cancer chemotherapy, radiation therapy, and surgery.
Before giving ONDEWAR SYRUP, to your child, inform your doctor if your child have or had severe constipation, heart problems, liver, kidney problems, imbalance with the levels of salts in your blood, (potassium, sodium, and magnesium), or have been scheduled for any surgery. During the therapy, your doctor would regularly monitor your child’s health to avoid the risk of side effects.
Your doctor will prescribe the right dose and duration depends on the child’s age, body weight and health condition, so stick to the dose, time, and duration prescribed by the doctor. Minor and temporary side effects may be experienced after the intake of this medicine. These includes headache, flushing and constipation.
Generally, these effects subside once the child’s body adapts to the medicine. However, in case of prolonged or bothersome events, consult your doctor immediately without any delay. Inform your doctor about your child’s complete medical history including any previous episodes of allergies.
USES OF ONDEWAR SYRUP
- Used to prevent nausea and vomiting in children caused by cancer chemotherapy, radiation therapy, and surgery
HOW ONDEWAR SYRUP WORKS
ONDEWAR SYRUP is a serotonin 5-HT3 receptor antagonist (specific chemical receptor), and it works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.
DIRECTIONS FOR USE
Always give this ONDEWAR SYRUP to your child as instructed by your doctor. Shake well before use. It is for pediatric use. Your doctor will prescribe the right dose depends on your child’s age body weight and disease condition.
SIDE EFFECTS OF ONDEWAR SYRUP
COMMON
- headache
- constipation
- weakness
- tiredness
- chills and drowsiness
RARE
Stop giving ONDEWAR SYRUP and contact your doctor immediately if your child experience any of the following side effects:
- severe allergic reaction which may include a red and lumpy skin rash (hives), difficulty with breathing, sudden wheezing, swelling of the face, mouth, lips or eyelids or a high temperature (fever)
HOW TO MANAGE SIDE EFFECTS
Headache:
Give plenty of water and apply a wet or cold cloth on child’s forehead. Apply pain balm to head to ease off the pain. If there is no improvement in the symptom, contact your doctor.
Constipation:
Give more fiber-rich foods like green leafy vegetables and fruits. Give lots of water. If there is no improvement in the symptom, contact your doctor.
WARNING & PRECAUTIONS
DRIVING AND USING MACHINES
Do not allow your child drive or play outdoors, as ONDEWAR SYRUP may cause dizziness or blurry vision. Consult your doctor before giving ONDEWAR SYRUP.
KIDNEY
ONDEWAR SYRUP should be used with caution if the child has kidney disease. Consult your doctor before giving ONDEWAR SYRUP.
LIVER
ONDEWAR SYRUP should be used with caution if the child has liver disease. Consult your doctor before giving ONDEWAR SYRUP.
ALLERGY
Do not use ONDEWAR SYRUP if your child is allergic (hypersensitive) to Ondansetron or any other ingredients of this medicine.
HEART DISEASE
ONDEWAR SYRUP should be used with caution if your child has any heart disease. If needed, dose will be adjusted accordingly. Consult your doctor for advice.
OTHERS
Before giving ONDEWAR SYRUP, inform your doctor if your child had or have:
- problems with the levels of salts in the blood, such as potassium, sodium, and magnesium
- severe constipation or gut problems like blockage
- are intolerant to some sugars (Ex. fructose intolerance)
Use in pediatrics:
Your doctor will prescribe the right dose and frequency depends on your child’s age, body weight and disease condition. Consult your doctor before giving ONDEWAR SYRUP.
INTERACTIONS
A. Drug-Drug Interactions:
Before using ONDEWAR SYRUP, inform your doctor if your child is taking any of the following medicine:
- medicines used to treat fits/epilepsy (ex. phenytoin, carbamazepine)
- medicines used to treat lung infections (ex. rifampicin)
- tramadol (used to treat severe pain)
- medicines used to treat heart problems such as abnormal heart beats (anti-arrhythmic ex. amiodarone)
- cancer medicines (ex. doxorubicin, daunorubicin and monoclonal, trastuzumab)
- medicines used to treat infections (erythromycin, ketoconazole)
Overdosage:
If your child accidentally takes too much of ONDEWAR SYRUP, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Ondansetron |
| Pharmacological Category | : | Serotonin antagonist |
| Therapeutic Indication | : | Nausea and Vomiting in patients (undergoing chemotherapy, radiotherapy, surgery) |
| Dosage Forms | : | Tablet, Injection, Dispersible Tablet, Syrup, Suspension, Oral strips, Lozenges, Pastille |
MORE INFORMATION
- Keep the medicine out of reach in children
- Store ONDEWAR SYRUP at room temperature
FAQs ABOUT ONDEWAR SYRUP
Q: What ONDEWAR SYRUP is used for?
A: ONDEWAR SYRUP is generally given before any major surgery or before chemotherapy and radiotherapy sessions. In case your child is about to undergo any of the above procedures, the doctor may ask you to give ONDEWAR SYRUP to your child to prevent vomiting post-procedure.
Q: What if my child takes too much ONDEWAR SYRUP?
A: ONDEWAR SYRUP is unlikely to cause harm if you give an extra dose by mistake. However, you must still tell your child’s doctor immediately.
Q: Can other medicines be given at the same time as ONDEWAR SYRUP?
A: ONDEWAR SYRUP may interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting ONDEWAR SYRUP. Also, check with your child’s doctor before giving any medicine to your child.
Q: For how long should I give ONDEWAR SYRUP?
A: Your doctor might advise you on how long your child should continue to take ONDEWAR SYRUP. You will need to consult your doctor from time to time to review the child’s treatment and assess the symptoms.
Q: What are the side effects are seen with ONDEWAR SYRUP?
A: The most common side effects include ONDEWAR SYRUP are headache, flushing (feeling of warmth), constipation. Consult your doctor if the above side effects persist for a long time.
REFERENCES
1. KD. Tripathi. Section 11, Gastrointestinal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 661.
2. Alexandria Griddine, Jeffery S. Bush. Ondansetron Book from Stat Pearls Publishing, Treasure Island (FL), 16 May 2018 PMID: 29763014. [Revised on September 2021] [Accessed on 21st June 2022] https://europepmc.org/article/nbk/nbk499839
3. Apollo Pharma Ltd, Unit 1, Irwell Works, Lower Woodhill Road, Bury, BL8 1AA, UK, PL 14308/0015 [ Revised on June 20] [Accessed on 21st June 20221] https://www.medicines.org.uk/emc/files/pil.6049.pdf
4. Leeford. [Accessed on 21st June 20221] https://www.leeford.in/product/145/vomishield-drops
AUTHOR DETAILS
Written By Dr. Janet.C, Pharm.D
Last updated on 21 Jan 2023 | 09:28 AM(IST)
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.