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INTRODUCTION
OLSTAN 20MG contains Olmesartan which belongs to the group of medicines called Angiotensin II receptor antagonist. It is used to treat high blood pressure(hypertension) in adults, children, and adolescents (6 years to less than 18 years). Hypertension is a condition in which the force of the blood against the blood vessel walls is too high which is characterized by headache, irregular heartbeat, vision changes, feeling of overtiredness, nausea, vomiting, confusion, anxiety, chest pain
Olmesartan makes blood vessels to relax and thus lowers the blood pressure by blocking the effects of Angiotensin II (a substance produced in your body which causes narrowing of blood vessels). Your doctor may advice you to take regular exercise, such as walking or swimming, low salt diet, giving up smoking and alcohol drinking. It is important to follow this advice from your doctor which helps to reduce blood pressure. Your doctor may check your kidney function, blood pressure, and the amount of electrolytes (Ex. potassium) in your body prior to the treatment or at regular intervals along with the treatment.
OLSTAN 20MG should be used in caution with patients having kidney, liver, and heart problems. If you are a pregnant or breast-feeding woman, consult your doctor for advice before taking OLSTAN 20MG. It is not recommended for use in children below 6 years of age and should be used with caution in children and adolescents of 6-18years of age. OLSTAN 20MG should be used with caution in patients above 65 years of age. The most common side effects of taking OLSTAN 20MG are dizziness, nausea, headache, diarrhea. Consult your doctor if the symptoms worsen.
USES OF OLSTAN 20MG
- Treats high blood pressure (hypertension)
HOW OLSTAN 20MG WORKS
OLSTAN 20MG makes blood vessels to relax and thus lowers the blood pressure by blocking the effects of Angiotensin II (substance produced in your body which causes narrowing of blood vessels).
DIRECTIONS FOR USE
Take OLSTAN 20MG as advised by your physician. Swallow this medicine, do not crush or chew OLSTAN 20MG. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF OLSTAN 20MG
COMMON
- dizziness
- headache
- nausea
- diarrhoea
- stomach pain
- gastroenteritis characterised by diarrhoea, cramps, nausea, vomiting and low-grade fever
- tiredness
- sore throat
- runny or stuffy nose
- signs of bronchitis such as coughing up thickened mucus and shortness of breath
- flu-like symptoms (Ex. fever, chills, cough, runny nose)
- cough
- pain in the chest, back, bones or joints
- signs of urinary tract infection (bladder pain, foul smell, cloudy urine, frequent urination)
- swelling of ankles, feet, legs, hands, or arms
- blood in the urine
- signs of increased uric acid levels such as severe joint pain, joint stiffness, difficulty in moving affected joints, redness and swelling
UNCOMMON
- rapid allergic reactions that may cause breathing problems, rapid fall of blood pressure that may even lead to fainting (anaphylactic reactions)
- feeling of spinning (vertigo)
- vomiting
- weakness
- feeling unwell
- muscular pain
- allergic skin rash
- itching
- exanthema (skin eruption)
- skin lumps (wheals)
- angina (pain or uncomfortable feeling in the chest)
- signs of low platelet count include easy bruising, prolonged bleeding from cuts
RARE
- lack of energy
- muscle cramps
- signs of kidney failure such as loss of appetite, decreased urinary output, fatigue
- signs of high potassium level like muscle spasms, abnormal heart rhythm
Stop taking OLSTAN 20MG and contact your doctor immediately if you experience any of the following side effects:
- allergic reactions causing swelling of the face, mouth and/or larynx (voice box), itching and rash
- blood pressure fall too low in susceptible individuals or because of allergic reaction which could cause severe light-headedness or fainting (more often in older people)
HOW TO MANAGE SIDE EFFECTS
Vomiting:
Take OLSTAN 20MG with, or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks, and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Consult your doctor if your symptom does not improve.
Diarrhea:
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.
Stomach pain:
Try to rest and relax. Try to have smaller and frequent meals. Keep a heat pad on your stomach. If the symptom does not improve, contact your doctor.
Dizziness:
When you feel dizzy, lie, or sit down immediately. if you're experiencing a severe episode of vertigo, lie in a dark and quite place with eyes closed. Vehicle driving should be avoided if you experience frequent dizziness without warning. Talk to your doctor if the symptom worsens.
WARNING & PRECAUTIONS
PREGNANCY
OLSTAN 20MG is not recommended in early pregnancy and must not be taken when more than 3 months pregnant, as it may cause serious harm to the baby if used after 3 months of pregnancy. Consult your doctor before taking this medicine.
BREASTFEEDING
OLSTAN 20MG is not recommended for use in breastfeeding women. Your doctor may choose another treatment especially if you want to breast-feed when your baby is new-born or born prematurely. Consult your doctor for advice before taking this medicine.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you feel dizzy or sleepy after taking OLSTAN 20MG. Consult your doctor before taking OLSTAN 20MG.
KIDNEY
OLSTAN 20MG should be taken with caution in patients with kidney problems. Consult your doctor before taking OLSTAN 20MG.
LIVER
OLSTAN 20MG should be used with caution in patients having liver disease. Consult your doctor before taking OLSTAN 20MG.
ALLERGY
OLSTAN 20MG is not recommended for use if you are allergic to Olmesartan.
HEART DISEASE
OLSTAN 20MG should be taken with caution in patients having heart failure, problem with heart valves or heart muscles. Before taking OLSTAN 20MG consult with your doctor.
OTHERS
OLSTAN 20MG is not recommended for use if you:
- have jaundice (yellowing of the skin and eyes)
- problems with drainage of the bile from the gallbladder due to gallstones
Before taking OLSTAN 20MG, inform your doctor if you have:
- severe vomiting, diarrhoea, or if you are on a low salt diet
- problems with adrenal glands
Use in pediatrics:
- OLSTAN 20MG is not recommended for use in children below 6 years of age and should be used with caution in children and adolescents of 6-18 years of age. Consult your doctor before taking OLSTAN 20MG.
Use in geriatrics:
- OLSTAN 20MG is used with caution in elderly patients above 65 years of age. Before taking OLSTAN 20MG, consult your doctor.
INTERACTIONS
A. Drug - Drug interactions:
Before taking OLSTAN 20MG, inform your doctor if you are taking any of the following medicine:
- aliskiren or angiotensin converting enzyme inhibitors used to treat high blood pressure (Ex. enalapril, lisinopril, ramipril)
- diuretics such as furosemide, hydrochlorothiazide (used to treat oedema or high blood pressure)
- potassium supplements and potassium-containing salt substitutes that rise the potassium level in body
- heparin (medicine used to prevent blood clot)
- non-steroidal anti-inflammatory drugs – medicines used to treat pain and inflammation (Ex. aspirin, ibuprofen)
- medicines containing lithium (used to treat some types of depression)
- colesevelam (medicine that lowers the level of cholesterol in your blood)
- antacids like magnesium hydroxide, calcium carbonate (medicines used to treat indigestion and heart burn)
Overdosage:
If you or anyone else accidentally take too much of OLSTAN 20MG, consult your doctor immediately or visit the nearby hospital. The most common symptoms of overdose are low blood pressure, fast heart rate, low heart rate (bradycardia) if vagal nerve stimulation occurs.
SYNOPSIS
| Drug | : | Olmesartan |
| Pharmacological Category | : | Angiotensin II Receptor Blocker |
| Therapeutic Indication | : | Hypertension |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep OLSTAN 20MG out of reach of children
- Store at room temperature
FAQs ABOUT OLSTAN 20MG
Can OLSTAN 20MG be used to treat high blood pressure?
OLSTAN 20MG can be considered as a drug of choice for high blood pressure. It contains Olmesartan which helps to relax the blood vessels and then normalize the blood pressure. Although, OLSTAN 20MG can treat high blood pressure, you doctor might treat you with other drugs depending upon your condition.
Can OLSTAN 20MG be given to children and adolescents?
OLSTAN 20MG is not recommended for use in children below 6 years of age and should be used with caution in children and adolescents of 6-18years of age. Consult your doctor before taking OLSTAN 20MG.
What happens if I stop taking OLSTAN 20MG?
Do not stop taking OLSTAN 20MG without talking to your doctor first. Stopping this medicine suddenly can cause your blood pressure to spike and may increase the risk for heart attack or heart failure.
Can OLSTAN 20MG be taken by patients with kidney problems?
OLSTAN 20MG should be taken with caution in patients with kidney problems. Kindly inform your doctor if you have any existing kidney disease. Your doctor may check the kidney function before prescribing this medicine.
What precautions do I need to follow while taking OLSTAN 20MG?
Patients taking OLSTAN 20MG must inform their doctor about their pre-existing disease conditions like kidney, heart, or liver problems. Consult your doctor immediately if you experience any unusual symptoms after taking OLSTAN 20MG.
REFERENCES
1. KD. Tripathi. Drugs Affecting Renin Angiotensin System. Essentials of medical pharmacology. Eighth edition. 2019. Page –535-538.
2. Xiaoshen Zhang, Han Zhang, Yuxia Ma, Wenliang Che and Michael R. Hamblin. Management of Hypertension Using Olmesartan Alone or in Combination. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. June 2017. [Accessed 19th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446820/
3. Kazuomi Kario, Ikuo Saito, Toshio Kushiro, Satoshi Teramukai, Mai Yaginuma, Yoshihiro Mori, Yasuyuki Okuda, Fumiaki Kobayashi and Kazuyuki Shimada. Persistent olmesartan-based blood pressure–lowering effects on morning hypertension in Asians: the HONEST study. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. May 2016. [Accessed 19th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865473/
4. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in February 2022]. [Accessed 19th May 2022] https://www.medicines.org.uk/emc/files/pil.7987.pdf
5. Daiichi Sankyo. U.S. Food & Drug Administration [Revised in May 2011] [Accessed 19th May 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021286s020lbl.pdf
USEFUL DIAGNOSTIC TESTS
- kidney function test
- electrolyte test
VIDEOS
Olmesartan TABLET - Drug Information
Olmesartan TABLET : Therapeutic Uses, Warning and Precautions, Interactions, Directions for Use, Side Effects and Storage
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