INTRODUCTION

OLMILACE 40 contains Olmesartan which belongs to a group of medicines called angiotensin-II receptor antagonists. It is used to treat blood pressure by relaxing the blood vessels. High blood pressure is a condition in which the blood vessels have persistently raised pressure. It can increase the risk of heart, brain, kidney and other diseases. When your heart pumps into the narrowed arteries blood pressure gets increased and it is determined by both, the amount of blood your heart pumps and the amount of resistance to blood flow in your arteries.

Angiotensin II has vasoconstrictor effect which increases blood pressure and water and sodium content in the body. OLMILACE 40 blocks the vasoconstrictor effects of angiotensin II thereby reducing the blood pressure. Before taking this medicine, inform your doctor if you have kidney or liver problems. Your doctor will monitor your kidney function, blood pressure, and potassium levels in your blood at regular intervals while you are taking this medicine.

Take OLMILACE 40 according to the dose and frequency as advised by your doctor. Swallow it as a whole. Do not chew, crush or break the medicine. Your doctor decides upon the dose you take depending on your age, other medications you are taking and whether you have any kidney or liver problems. Do not drive or operate machinery while taking this medicine, since it may cause sleepiness or dizziness. It is not recommended for children from 1 year to less than 6 years of age. The common side effects are dizziness, headache, diarrhea and indigestion.

USES OF OLMILACE 40

• Treats high blood pressure (hypertension)

HOW OLMILACE 40 WORKS

OLMILACE 40 blocks the effect of a substance called angiotensin II in our body. Angiotensin II causes narrowing of blood vessels. Olmesartan by blocking its action allows your blood vessels to relax and thus reduces blood pressure.

DIRECTIONS FOR USE

Take this medicine according to the dose and frequency as advised by your doctor. Swallow it as a whole. Do not chew, crush or break the medicine. It may be taken with or without food.

SIDE EFFECTS OF OLMILACE 40

HOW TO MANAGE SIDE EFFECTS

Diarrhea:

Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.

Drowsiness or dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

Feeling sick (nausea) or indigestion:

Stick to simple meals and do not eat rich or spicy foods.

Stomach ache:

Place a warm bottle or heated bag on your abdomen. Soak in a warm bath. Drink plenty of clear fluids and water.

Cough:

Drink sufficient quantity of fluids which helps to thin the mucus in your throat. Suck on cough drops or hard candies.  

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:

• enalapril, lisinopril, ramipril
• aliskiren
• potassium supplements
• heparin
• lithium
• ibuprofen, aceclofenac
• colesevelam hydrochloride
• antacids

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT OLMILACE 40

How does OLMILACE 40 work?

It is a type of blood pressure-lowering medicine called an angiotensin receptor blocker. It relaxes and widens your blood vessels.

Is OLMILACE 40 safe to take for a long time?

It is generally safe to take for a long time. In fact, it works best when you take it for a long time. Consult your doctor for advice.

REFERENCES

1. KD Tripathi MD. Drugs affecting renin-angiotensin system and plasma kinins. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page - 507.

2. Pfeffer MA, Opie LH. Inhibitors of the Renin-Angiotensin-Aldosterone System. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. Page - 158.

3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page - 1017.

4. K O Stumpe & M Ludwig. Antihypertensive efficacy of olmesartan compared with other antihypertensive drugs: Journal of human hypertension. April 24, 2002 [Accessed Oct 17, 2020] https://www.nature.com/articles/1001395

5. Mylan Hungary Kft, Electronic Medicines Compendium (EMC); [Revised April 2017] [Accessed Oct 17, 2020] https://www.medicines.org.uk/emc/files/pil.8787.pdf 

6. Daiichi Sankyo, Inc. 2002; U.S. Food & Drug Administration; [Revised on 2009] [Accessed Oct 17, 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021286s023lbl.pdf