INTRODUCTION

OFRON M SYRUP is a combination of Metronidazole, Ofloxacin and Simethicone which belongs to the group of medicines called Antibiotics and Gastrointestinal agents respectively. It is used to treat gastrointestinal infections, chest infections, diarrhoea & dysentery, amoebiasis, intra-abdominal infections, gastroenteritis, antibiotic associated colitis, giardiasis, anaerobic infections, inflammatory bowel syndrome, bloating and distension.

Avoid taking alcohol with OFRON M SYRUP. It is not recommended in patients with kidney problems and epilepsy. OFRON M SYRUP should be used with caution in patients with dermatitis. OFRON M SYRUP should be used with caution in pregnant women. Contact your doctor before taking. OFRON M SYRUP should be used with caution in breastfeeding women. Contact your doctor before taking.

The most common side effects of taking OFRON M SYRUP are agitation, sleep disorder, insomnia, muscle, joint pain, dizziness, headache, eye irritation, vertigo, abdominal pain, nausea, vomiting, unpleasant taste in the mouth, dry mouth, weight loss, diarrhoea, loss of appetite, photosensitivity, hallucination, and sinus tachycardia. Contact your doctor if you experience any side effects.

USES OF OFRON M SYRUP

It is used to treat conditions such as:

• gastrointestinal infections
• chest infections
• diarrhoea, dysentery
• amoebiasis
• intra-abdominal infections
• gastroenteritis
• antibiotic associated colitis
• giardiasis
• anaerobic infections
• inflammatory bowel syndrome
• bloating and distension

HOW OFRON M SYRUP WORKS

OFRON M SYRUP acts synergistically against bacteria and protozoa both kind of pathogens. Metronidazole acts against the microorganisms by destroying the DNA of the bacteria. Ofloxacin against the bacteria by preventing them from repairing themselves and inhibits reproduction. Simethicone breaks down gas bubbles to make it easier for gas to travel through the body.

DIRECTIONS FOR USE

Take OFRON M SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you, based on your age, body weight, disease condition.

SIDE EFFECTS OF OFRON M SYRUP

HOW TO MANAGE SIDE EFFECTS

Diarrhea

Consume lots of water and fruit juice which keeps yourself hydrated. Contact your doctor if diarrhoea worsens.

Dizziness Or Drowsiness

Take rest and relax. Get enough sleep. Avoid driving or operate any machines if you feel dizzy. Do not take alcohol, as it can increase dizziness. Contact your doctor if the dizziness does not improve.

Headache

Rest and relax. Consume lots of water and electrolytes. Use a pain-relieving balm if necessary. Do not consume alcohol. Contact your doctor if the headache persists.

Nausea And Vomiting

Take the medication right before or after eating. Stick to simple meals. Avoid eating oily or spicy food. If the nausea and vomiting does not improve, consult your doctor.

Stomach Pain

Try to rest and relax. Eat small meals but take frequently. Keep a heat pad on your stomach. Contact your doctor if the abdominal pain did not improve.

WARNING & PRECAUTIONS

PREGNANCY

Use with Caution

OFRON M SYRUP should be used with caution in pregnant women. Contact your doctor before taking.

BREASTFEEDING

Use with Caution

OFRON M SYRUP should be used with caution in breastfeeding women. Contact your doctor before taking OFRON M SYRUP.

DRIVING AND USING MACHINES

Use with Caution

Do not drive or operate heavy machinery after taking OFRON M SYRUP. Contact your doctor before taking OFRON M SYRUP.

KIDNEY

Contraindicated

OFRON M SYRUP is not recommended for use in patients with kidney problem. Contact your doctor before taking OFRON M SYRUP.

ALLERGY

Contraindicated

Do not take OFRON M SYRUP if you are allergic to Metronidazole, Ofloxacin, Simethicone or to any other ingredients of this medicine.

INTERACTIONS

A. Drug-Drug interactions:

Before taking OFRON M SYRUP inform you are taking the following medicines:

• rifampicin (medicine used for tuberculosis)
• ciclosporin (medicine used in cases of organ transplantation)
• antibiotics such as azithromycin (medicine used for bacterial infection)
• medicines used for heart problems such as arrhythmia (Ex. amiodarone)
• antipsychotics (medicines used to treat psychoses)
• antimicrobials (medicine used to treat infection)
• anticoagulants (medicines used for treating blood clotting disorders)

Overdosage:

If you or anyone else accidentally takes too much of OFRON M SYRUP, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep OFRON M SYRUP out of reach of children
• Store OFRON M SYRUP in a cool, dry place

FAQs ABOUT OFRON M SYRUP

Q: What is OFRON M SYRUP used for?

A: OFRON M SYRUP is used to treat gastrointestinal infections, chest infections, diarrhoea & dysentery, amoebiasis, intra-abdominal infections, gastroenteritis, antibiotic associated colitis, giardiasis, anaerobic infections, inflammatory bowel syndrome, bloating and distension. Consult your doctor before taking OFRON M SYRUP.

Q: Is OFRON M SYRUP safe in pregnancy?

A: OFRON M SYRUP should be used with caution in pregnant women. Contact your doctor before taking.

Q: How OFRON M SYRUP work?

A: OFRON M SYRUP acts synergistically against bacteria and protozoa both kind of pathogens. Metronidazole acts against the microorganisms by destroying the DNA of the bacteria. Ofloxacin against the bacteria by preventing them from repairing themselves and inhibits reproduction. Simethicone breaks down gas bubbles to make it easier for gas to travel through the body.

Q: What are the side effects of taking OFRON M SYRUP?

A: The common side effects of taking OFRON M SYRUP are headache, gastrointestinal effects such as diarrhoea, stomach pain, constipation, wind (flatulence), benign polyps (cell masses) in the stomach, nausea or vomiting and dry mouth. Contact your doctor if you experience any side effects.

Q: Can I stop taking OFRON M SYRUP if I feel, better?

A: No, continue taking OFRON M SYRUP even if you feel better. Abruptly stopping the treatment course may result in the reoccurrence of symptoms.

REFERENCES

1. KD. Tripathi. Sulfonamides, Cotrimoxazole and Quinolones, Antiamoebic and Other Antiprotozoal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 713, 837.

2. Bethesda (MD). Simethicone. National Institute of Health. NLM. National centre for biotechnology information. PubChem. 2004. [Accessed on 11th March 2023] https://pubchem.ncbi.nlm.nih.gov/compound/Simethicone

3. Leeford Healthcare Ltd. Ofloxacin, Metronidazole, Simethicone. [Accessed on 11th March 2023] https://www.leeford.in/product/410/oltef-m

4. Innovative Pharmaceuticals Pvt Ltd. Ofloxacin, Metronidazole, Simethicone. [Accessed on 11th March 2023] https://vibcare.co.in/omeprazole-domperidone/

5. Mypher Pharma. Ofloxacin, Metronidazole, Simethicone. [Accessed on 11th March 2023] https://mypherpharma.com/diacoli-om-60ml.html

6. Elkos Healthcare Pvt Ltd. Ofloxacin, Metronidazole, Simethicone. [Accessed on 11th March 2023] https://www.elkosgroup.in/product-details.php?name=OFLOKOS-M

7. Invision Medi Sciences. Ofloxacin, Metronidazole, Simethicone. [Accessed on 11th March 2023] http://www.invisionmedi.com/category/inflobactms-susp.htm

8. Santo Medi Sciences Pvt Ltd. Ofloxacin, Metronidazole, Simethicone. [Accessed on 11th March 2023] https://www.santomedisciences.com/product/ofloxacin-50-mg-metronidazole-120-mg-simethicone-10-mg-5-ml-suspensions

9. Bio Sync Pharma Pvt Ltd. Ofloxacin, Metronidazole, Simethicone. [Accessed on 11th March 2023] https://www.biosyncpharma.in/product/ofia-susp/

10. Kenn Lifesciences. Ofloxacin, Metronidazole, Simethicone. [Accessed on 11th March 2023] https://kennlifesciences.com/product/ofloxacin-50mg-metronidazole-120-mg-simethicone-10mg/

USEFUL DIAGNOSTIC TESTS

• Complete Blood Count
• Peripheral Examination

AUTHOR DETAILS

Written By Dr. Janet.C, Pharm.D
Last updated on 14 Mar 2023 | 04:41 PM(IST)