INTRODUCTION

NUTIN 12.5MG contains Atenolol which belongs to the group of medicines called beta-blockers. It is used in the treatment of high blood pressure (hypertension) and arrhythmia (uneven heart beats). High blood pressure (hypertension) is a condition in which the blood exerts an increased pressure against the walls of blood vessels. If left untreated, it may lead to damage of blood vessel, kidney problems, stroke and other heart problems. Arrhythmia is a heart condition in which there is an improper generation or conduction of cardiac impulses which affects the normal cardiac rhythm.

NUTIN 12.5MG can be used in the prevention of angina pectoris (chest pain) and also offers protection to the heart in the early treatment after a heart attack (myocardial infarction). Atenolol acts by slowing the heart rate and force of contraction which makes your heart pump slowly with less force. Along with the treatment, your doctor might ask you to make certain lifestyle changes such as quitting alcohol and smoking, improve your sleep at night, eating a healthy diet and manage weight.

The most common side effect of taking this medicine is an initial decrease in pulse rate. This is usually normal and disappears with time. However, if it bothers you contact your doctor. Others include nausea, dizziness and tiredness. Before taking this medicine, inform your doctor if you have any other heart problems or kidney problems. NUTIN 12.5MG should be used with caution in pregnant or breastfeeding women and in elderly patients. Consult your doctor before taking. Do not use this medicine in children under 18 years without consulting a doctor.

USES OF NUTIN 12.5MG

• Treats high blood pressure and arrhythmia (uneven heart beats)
• Prevents angina pectoris (chest pain) and recurrence of heart attack

HOW NUTIN 12.5MG WORKS

Following oral administration, atenolol selectively binds to and inhibits the activity of beta 1-adrenergic receptors, which reduces the heart rate, force of contraction and cardiac output, leading to decrease in blood pressure. It also decreases cardiac workload and oxygen demand which helps in protecting the heart against heart attack and chest pain.

DIRECTIONS FOR USE

Take this medicine as directed by your physician. Swallow the medicine as whole with a sip of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, weight and health condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF NUTIN 12.5MG

HOW TO MANAGE SIDE EFFECTS

Feeling sick (nausea):

Try taking this medicine with, or just after meals. Stick to simple meals. Do not eat rich or spicy food.

Diarrhea:

Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.

Headache:  

Rest and drink plenty of fluids. Do not drink too much alcohol.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid traveling, driving or operating any tools or machines while you are feeling dizzy. If the symptom still persists, contact your doctor for advice.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor, if you are taking,

• other medicines used to treat high blood pressure or chest pain (e.g. furosemide, guanethidine, reserpine, captopril, enalapril, verapamil, diltiazem and nifedipine)
• medicines used to treat abnormal heartbeat (e.g. disopyramide, quinidine, amiodarone, digoxin or procainamide)
• medicines used to treat inflammation or pain (e.g. Ibuprofen or indomethacin)
• medicines used to treat diabetes (e.g. metformin, gliclazide, rosiglitazone or insulin)
• clonidine (a medicine used to treat both high blood pressure and migraine)
• adrenaline or noradrenaline (affects that stimulation of your heart)
• lidocaine (a local anesthetic)
• medicines to treat nasal congestion (e.g. oxymetazoline)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT NUTIN 12.5MG

Can NUTIN 12.5MG cause bradycardia?

Yes. It can initially cause a decrease in pulse rate (bradycardia) in some individuals. This is usually normal and disappears with time. However, if it bothers you contact your doctor.

Can NUTIN 12.5MG be taken twice a day?

Take this medicine as directed by your physician. Your doctor will decide the correct dose and duration for you depending upon your age, weight and health condition. If required, it can be taken twice daily also, based on the comments of your doctor.

Can NUTIN 12.5MG be crushed?

No. Swallow the medicine as whole with a sip of water. Do not crush or chew the medicine.

REFERENCES

1. KD. Tripathi. Antihypertensive Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 563-564.

2. Thomas Michel and Brian B. Hoffmann. Treatment of myocardial ischemia and hypertension. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 327.

3. Gerald G. Briggs and Roger K. Freeman. A. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 306-317.

4. Merck KGaA. A Randomized Controlled Study to Assess the Effects of Bisoprolol and Atenolol on Resting Heart Rate and Sympathetic Nervous System's Activity in Subjects with Essential Hypertension. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on March 2017] [Accessed 8th December 2020] https://clinicaltrials.gov/ct2/show/NCT01251146

5. L Hansson, B E Karlberg, H Aberg, A Westerlund, N C Henningsen, S Jameson. Clinical evaluation of atenolol in hypertension. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. December 1976. [Accessed 8th December 2020] https://pubmed.ncbi.nlm.nih.gov/799559/

6. Accord Healthcare Limited. Electronic Medicines Compendium (EMC); [Revised on March 2016] [Accessed 8th December 2020]. https://www.medicines.org.uk/emc/files/pil.6024.pdf

7. AstraZeneca. Health Products Regulatory Authority (HPRA). [Revised on February 2019] [Accessed 8th December 2020] https://www.hpra.ie/img/uploaded/swedocuments/1870259e-a863-4f23-a8cd-db47130ff0b5.pdf

USEFUL DIAGNOSTIC TESTS

• ECG (Electrocardiogram)
• Blood pressure measurement