Noklot 75mg Tablet 10'S

Thrombotic Disorder Rx required

Best Price* ₹ 62.20 MRP ₹ 77.75
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Bayer Zydus Pharma Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

NOKLOT 75MG contains Clopidogrel which belongs to a group of medicines called Antiplatelets. NOKLOT 75MG is used in adult patients to prevent blood clots (thrombi) due to atherothrombosis which may lead to atherothrombotic events such as stroke, or heart attack. Atherothrombosis is an inflammatory process of the arteries that affects the coronary (heart), cerebral (brain) and peripheral circulation (blood circulation to arms, hands, legs and feet) by aberrant thickening of the blood vessel wall and reducing the blood flow to the tissue that triggers the occurrence of myocardial infarction, stroke and peripheral arterial disease.

Clopidogrel is an antiplatelet which works by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots that results in the lower chance of occurrence of heart attack or stroke. Along with this treatment, your doctor may advise regular blood tests to check your blood clotting time.

Avoid taking NOKLOT 75MG, if you are allergic to Clopidogrel, or have a medical condition that is currently causing bleeding such as a stomach ulcer or bleeding within the brain, severe liver disease. Before taking NOKLOT 75MG, inform your doctor if you are at a risk of internal bleeding, have or ever had a clot in artery of your brain (ischemic stroke) which might have occurred within the last seven days, or have heart or kidney problems. NOKLOT 75MG is not recommended for use in pregnant and breastfeeding women which is also not recommended for use in children and adolescents (below 18 years of age). Consult your doctor before taking NOKLOT 75MG. The most common symptoms of taking NOKLOT 75MG are bleeding, diarrhea, abdominal pain, indigestion, and heartburn. Consult your doctor if any of these symptoms gets worse.

USES OF NOKLOT 75MG

  • Prevent blood clots (thrombi) due to atherothrombosis (and reduces the risk of heart and stroke) in adult patients

HOW NOKLOT 75MG WORKS

NOKLOT 75MG works by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots that results in the lower chance of occurrence of heart attack or stroke.

DIRECTIONS FOR USE

Take NOKLOT 75MG as advised by your physician. Swallow NOKLOT 75MG with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF NOKLOT 75MG

COMMON

  • bleeding inside the head, lungs, stomach, bowels, eyes or joints
  • nose bleed
  • bruising
  • haematoma (unusual bleeding or bruising under the skin)
  • blood in the urine
  • diarrhoea
  • abdominal pain
  • indigestion
  • heartburn

UNCOMMON

  • headache
  • stomach ulcer
  • vomiting
  • nausea
  • constipation
  • excessive gas in stomach or intestines
  • rashes
  • itching
  • dizziness
  • sensation of tingling and numbness

RARE

  • vertigo (spinning sensation)
  • enlarged breasts in males

Stop taking NOKLOT 75MG and contact your doctor if you experience any of the following side effects:                                               

  • signs of  thrombotic thrombocytopenic purpura ( rare blood disorder) such as fever, whether or not associated with bleeding which appears under the skin as red pinpoint dots, with or without unexplained extreme tiredness, and confusion
  • signs of liver problems such as yellowing of the skin and/or the eyes (jaundice)
  • signs of allergic skin reaction such as swelling in the mouth, rashes, itching, and blisters of the skin

HOW TO MANAGE SIDE EFFECTS

Constipation:

Try to eat more high-fiber foods such as fresh fruit, vegetables, cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate treatments for constipation.

Dizziness:

Try to rest and relax and get enough sleep. Try to avoid driving or operating any tools or machines while you are feeling dizzy. Limit your consumption of alcohol, as it can aggravate your dizziness. Consult and inform your doctor if the symptom does not improve.

Headache:

If NOKLOT 75MG causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking NOKLOT 75MG. If headaches last more than a week or severe, inform your doctor.

Nausea and vomiting:

Try to take NOKLOT 75MG with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.

Indigestion:

Try to have smaller and more frequent meals and eat and drink slowly. Try to reduce consumption of tea, coffee, cola, or alcohol and lose weight if you are obese. Avoid smoking and don’t have rich, spicy, or fatty foods. Consult and inform your doctor if the symptom does not improve.

Diarrhoea:

Drink lots of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to treat diarrhea and consult your doctor if the symptom gets worse.

WARNING & PRECAUTIONS

PREGNANCY

[GBNKEYWORD is not recommended for use in pregnant women. Consult your doctor before taking NOKLOT 75MG.

BREASTFEEDING

[GBNKEYWORD is not recommended for use in breastfeeding women. Consult your doctor before taking NOKLOT 75MG.

DRIVING AND USING MACHINES

NOKLOT 75MG is unlikely to affect your ability to drive or to use machines. Consult your doctor before taking NOKLOT 75MG.

KIDNEY

NOKLOT 75MG should be used with caution in patients with kidney disease. Consult your doctor for advice before taking NOKLOT 75MG.

LIVER

NOKLOT 75MG is not recommended for use in patients with severe liver disease and it should be used with caution in patients with liver disease. Consult your doctor for advice before taking NOKLOT 75MG.

ALLERGY

NOKLOT 75MG is not recommended for use  if you are allergic to clopidogrel or any of the other ingredients of this medicine. Consult your doctor before taking NOKLOT 75MG.

OTHERS

NOKLOT 75MG is not recommended for use if you:

  • have a medical condition that is currently causing bleeding such as a stomach ulcer or bleeding within the brain

Before taking NOKLOT 75MG, inform your doctor if you:                                                                 

  • have a risk of bleeding such as a medical condition that puts you at risk of internal bleeding Ex. stomach ulcer, blood disorder that makes you prone to internal bleeding (bleeding inside any tissues, organs or joints of your body), recent serious injury, recent surgery (including dental), planned surgery (including dental) in the next seven days
  • have or had a clot in an artery of your brain (ischemic stroke) which occurred within the last seven days
  • had allergic reaction to any medicine used to treat your disease.
  • had a past medical history of non-traumatic brain hemorrhage (condition marked by bleeding inside brain in the absence of trauma or surgery)

Use in Pediatrics:

NOKLOT 75MG is not recommended for use in children and adolescents (below 18 years of age) since the medicine does not work in this population. Consult your doctor before taking NOKLOT 75MG.

Use in Geriatrics:

NOKLOT 75MG is used with caution in elderly patients (aged 65 years or above). Consult your doctor before taking NOKLOT 75MG.

INTERACTIONS

A.Drug-Drug Interactions:

Before taking NOKLOT 75MG, inform your doctor, if you are taking any of the following:

  • oral anticoagulants (medicines used to reduce blood clotting) such as dabigatran, rivaroxaban, apixaban
  • non-steroidal anti-inflammatory drugs (medicines used to treat painful and/or inflammatory conditions of muscle or joints) such as ibuprofen, naproxen, diclofenac
  • injectable medicine used to reduce blood clotting Ex heparin, enoxaparin
  • antiplatelet agent (medicine used to prevent formation of blood clot) Ex. ticlopidine
  • selective serotonin reuptake inhibitor (medicines used to treat depression) Ex. fluoxetine, fluvoxamine)
  • rifampicin (medicine used to treat severe infections)
  • omeprazole or esomeprazole (medicines used to treat upset stomach)
  • fluconazole or voriconazole (medicines to treat fungal infections)
  • antiretroviral drugs ( medicines used to treat HIV infections) Ex. efavirenz, atazanavir, darunavir, fosamprenavir
  • carbamazepine (medicine to treat some forms of epilepsy)
  • moclobemide (medicine used to treat depression)
  • repaglinide (medicine used to treat diabetes)
  • paclitaxel (medicine used to treat cancer)
  • opioids (medicines used to treat severe pain) Ex. oxycodone, hydrocodone, codeine

Overdosage:

If you or anyone else accidentally takes too much of NOKLOT 75MG, consult your doctor immediately or visit the nearby hospital. Overdosage may lead to increased risk of bleeding.

SYNOPSIS

Drug :   Clopidogrel
Pharmacological Category :   Antiplatelet
Therapeutic Indication :   Atherothrombosis
Dosage Forms :   Tablet

MORE INFORMATION

  • keep the medicine out of reach in children
  • store NOKLOT 75MG at room temperature

FAQs ABOUT NOKLOT 75MG

What NOKLOT 75MG is used for?

NOKLOT 75MG is used in adult patients to prevent blood clots (thrombi) due to atherothrombosis (condition marked by formation of blood clot within an artery) which leads to atherothrombotic events such as stroke, or heart attack.

How should [GBNKEYWORD be taken?

Take NOKLOT 75MG as advised by your physician. Swallow NOKLOT 75MG with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

What are the side effects of NOKLOT 75MG?

The most common symptoms of taking NOKLOT 75MG are bleeding, diarrhea, abdominal pain, indigestion, and heartburn. Consult your doctor if any of these symptoms gets worse.

Who should avoid taking NOKLOT 75MG?

NOKLOT 75MG is not recommended for use in patients allergic to Clopidogrel, have a medical condition that is currently causing bleeding such as a stomach ulcer or bleeding within the brain, or severe liver disease.

Is NOKLOT 75MG safe to use in children?

NOKLOT 75MG is not recommended for use in children and adolescents (below 18 years of age) since the medicine does not work in this population. Consult your doctor before taking NOKLOT 75MG.

REFERENCES

1. KD. Tripathi. Drugs Affecting Coagulation, Bleeding and Thrombosis. Seventh edition. 2013. Page – 630.

2. Mylan Pharmaceuticals. Food Study of Clopidogrel Bisulfate Tablets 75 mg to Plavix Tablets 75 mg. NIH U.S. National Library of Medicine ClinicalTrials.gov. Revised in April 2008] [Accessed on 31st May 2022] https://clinicaltrials.gov/ct2/show/NCT00650169

3. Craig J. Beavers; Imama A. Naqvi. Clopidogrel.  NIH National Library of Medicine, National center for biotechnology information. May 2022 [Accessed on 31th May 2022] https://www.ncbi.nlm.nih.gov/books/NBK470539/

4. Peng-Xin Ge , Li-Ping Jiang , Ting Tai , Ting Zhu , Jin-Zi Ji , Yi-Fei Li , Qiong-Yu Mi , Hong-Guang Xie. Short-term standard alcohol consumption enhances platelet response to clopidogrel through inhibition of the Nrf2/Ces1 pathway and induction of Cyp2c in mice.  NIH National Library of Medicine, National center for biotechnology information. PubMed.gov. August 2021 [Accessed on 31th May 2022] https://pubmed.ncbi.nlm.nih.gov/33626394/

5. Matthew T Roe , Shaun G Goodman, E Magnus Ohman, Susanna R Stevens, Judith S Hochman, Shmuel Gottlieb, Felipe Martinez, Anthony J Dalby, William E Boden, Harvey D White, Dorairaj Prabhakaran, Kenneth J Winters, Philip E Aylward, Jean-Pierre Bassand, Darren K McGuire, Diego Ardissino, Keith A A Fox, Paul W Armstrong. Elderly patients with acute coronary syndromes managed without revascularization: insights into the safety of long-term dual antiplatelet therapy with reduced-dose prasugrel versus standard-dose clopidogrel  NIH National Library of Medicine, National center for biotechnology information. PubMed.gov. August 2013 [Accessed on 31th May 2022] https://pubmed.ncbi.nlm.nih.gov/23852610/

6. APL Swift Services (Malta) Limited. Electronic medicines compendium (EMC). [Revised in March 2021] [Accessed on 31st May 2022] https://www.medicines.org.uk/emc/files/pil.5207.pdf

7. Sanofi Winthrop Industrie. Electronic medicines compendium (EMC). [Revised in September 2021] [Accessed on 31st May 2022] https://www.medicines.org.uk/emc/files/pil.5934.pdf

 

 

 

       

 

USEFUL DIAGNOSTIC TESTS

  • Complete blood count
  • Liver function tests

VIDEOS

Clopidogrel TABLET - Drug Information

Clopidogrel TABLET : Therapeutic Uses, Warning and Precautions, Interactions, Directions for Use, Side Effects and Storage

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    17.5 g
    Ingredient
    CLOPIDOGREL 75MG
    Hsn Code
    30049099
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Noklot 75mg Tablet 10'S

Noklot 75mg Tablet 10'S Mkt: Bayer Zydus Pharma Pvt Ltd

M.R.P.: Rs.77.75
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