INTRODUCTION

NIMSUTECH TABLET contains Nimesulide which belongs to the group of medicines called Non-steroidal anti-inflammatory drugs (NSAIDs). It is used to treat inflammatory conditions including joint disorders such as rheumatoid arthritis, post traumatic and post operative painful condition and fever. NIMSUTECH TABLET is also used to treat acute pain in orthopaedic, ENT, dental and mild to moderate pain of osteoarthritis and rheumatoid arthritis.

Your doctor might advise regular liver function tests during treatment with NIMSUTECH TABLET.

NIMSUTECH TABLET is usually advised as a second line of treatment for a short duration of time in order to relieve symptoms.

NIMSUTECH TABLET is not recommended in case of active stomach or duodenal ulcers, alcoholism, drug addiction, cerebrovascular bleeding or bleeding disorders, severe clotting disorders, severe heart, kidney or liver impairment, fever and/or flu-like symptoms, a history of recurrent ulceration or gastrointestinal bleeding.

NIMSUTECH TABLET is not recommended during the third trimester of pregnancy and in breast feeding women.

NIMSUTECH TABLET is not given to children and adolescents below 12 years of age. It should be used with caution in elderly patients.

The most common side effects of taking NIMSUTECH TABLET are vomiting, diarrhoea or nausea and changes in the level of liver enzymes. Consult your doctor if above side effects does not improve.

USES OF NIMSUTECH TABLET

It is used to treat inflammatory conditions including joint disorders such as:

• rheumatoid arthritis
• post traumatic
• post operative painful condition and
• fever

HOW NIMSUTECH TABLET WORKS

NIMSUTECH TABLET works by blocking the enzyme involved in the production of certain chemical substances during inflammation, which are responsible for causing pain, redness, swelling and fever in the body. Hence decreasing the fever, pain and swelling caused after injuries.

DIRECTIONS FOR USE

Take NIMSUTECH TABLET as advised by your physician. It can be taken with or without meals.

For Tablet, Capsule: Swallow NIMSUTECH TABLET with a glass of water. Do not crush or chew the medicine.

For Dispersible Tablet: Disperse NIMSUTECH TABLET in the specified quantity of water as mentioned in the label. Consume the mixture immediately after reconstitution.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Continue to take NIMSUTECH TABLET for the stipulated duration prescribed by your doctor to achieve better results.

SIDE EFFECTS OF NIMSUTECH TABLET

HOW TO MANAGE SIDE EFFECTS

Nausea or Vomiting:

Take this medicine just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. If the symptoms do not improve, contact your doctor.

Diarrhoea:

Drink lots of fluids, like water, fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. If the symptoms do not improve, contact your doctor.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking NIMSUTECH TABLET, inform your doctor if you are taking any of the following medicine:

• other medicine used to reduce inflammation (Ex. methyprednisolone)
• medicine used to treat blood clots (Ex. warfarin)
• medicine used in treatment of arthritis (Ex. methotrexate)
• medicines used in treatment of mental disorders (Ex. lithium)
• diuretics (Ex. furosemide) to rid the body of salt and water

Overdosage:

If you or anyone else accidentally takes too much NIMSUTECH TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are drowsiness, sluggishness, nausea, vomiting, and abdominal discomfort.

SYNOPSIS

MORE INFORMATION

• Keep NIMSUTECH TABLET out of reach of children
• Store at room temperature

FAQs ABOUT NIMSUTECH TABLET

Q: Can NIMSUTECH TABLET be taken for a longer duration?

A: No, NIMSUTECH TABLET is not recommended for a long period of time as it can lead to serious symptoms like ulcers and bleeding in the stomach. It is also known to cause kidney problems if taken for a long period of time. It should be taken for the duration as advised by the doctor.

Q: Can NIMSUTECH TABLET be taken along with food?

A: NIMSUTECH TABLET is usually recommended to be taken after eating your meals. It should not be taken with an empty stomach as it can lead to discomfort and irritation in the stomach along with pain. Consult your doctor before taking it.

Q: Can NIMSUTECH TABLET be taken during pregnancy?

A: NIMSUTECH TABLET is generally not recommended for use during pregnancy as it can cause malformations in the baby. Therefore, consult your doctor before taking it.

Q: What are the common side effects of NIMSUTECH TABLET?

A: The most common side effects are abdominal pain, diarrhoea (loose stools) and vomiting, nausea. If any of these symptoms get worse, contact your doctor immediately.

Q: Does NIMSUTECH TABLET make you dizzy?

A: Yes, NIMSUTECH TABLET can make you feel dizzy. Therefore, it is not advised to not drive or do any tiring work if you feel these symptoms as it may cause great harm. In you feel this symptom is disturbing, consult your doctor for advice.

REFERENCES

1. KD Tripathi. Nonsteroidal Antiinflammatory Drugs and Antipyretic-Analgesics. Essentials of Medical Pharmacology. Seventh Edition, 2013. Page - 203-204.

2. H G Kress , A Baltov , A Basinski, F Berghea, J Castellsague, C Codreanu, E Copaciu, M A Giamberardino ,M Hakl, L Hrazdira, M Kokavec, J Lejcko, L Nachtnebl, R Stancík, A Švec, T Tóth, M V Vlaskovska, J Woron. Acute pain: a multifaceted challenge - the role of nimesulide. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. 2016. [Accessed 20th July 2021] https://pubmed.ncbi.nlm.nih.gov/26414386/

3. A K Singla, M Chawla, A Singh. Nimesulide: some pharmaceutical and pharmacological aspects--an update. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. 2000. [Accessed 20th July 2021] Nimesulide: some pharmaceutical and pharmacological aspects--an update - PubMed (nih.gov)

4. Magis Farmaceutici. Isodol. (Nimesulide 100mg). [Revised on July 2022] [Accessed on 20th July 2022] https://www.magispharma.it/media/isodol/download/en/15700031575d9458d58342b.pdf

5. Pharm Evo Pvt Ltd. Nise (Nimesulide 100mg). [Revised on May 2016] [Accessed on 20th July 2022] https://pharmevo.biz/wp-content/uploads/2021/03/Nise.pdf

USEFUL DIAGNOSTIC TESTS

• Complete Blood Count
• Liver Function Test