Recently Searched
Choose Generic substitutes to Save up to 50% off 
Availability & Expiry
Cold Storage Product cannot be returned or exchanged. Available at selected pin codes.
INTRODUCTION
NIKOS 10MG TABLET contains Nicorandil which belongs to the group of medicines called Potassium channel activators. It is used in adults to prevent and reduce painful signs of angina pectoris who cannot take heart medicines called beta-blockers or calcium antagonists.
Angina pectoris is a type of temporary chest pain or discomfort which occurs as a result of decreased blood flow to the heart muscle which is usually not a heart attack but a sign of increased risk for heart attack that is generally characterized by symptoms such as squeezing pressure, heaviness, tightness or pain in the chest that can occur sudden or recur over time.
Avoid consumption of alcohol during treatment with NIKOS 10MG TABLET as it may reduce your blood pressure even more.
NIKOS 10MG TABLET is not recommended for use in patients with severe low blood pressure, low blood volume, heart problems (such as cardiogenic shock, left ventricular failure with low filling pressure or cardiac decompensation).
Before taking NIKOS 10MG TABLET, inform your doctor if you have lung problems such as pulmonary oedema (condition marked by fluid build-up in lungs), hepatic impairment or kidney problems.
NIKOS 10MG TABLET is not recommended for use in pregnant and breastfeeding women. It is also not recommended for use in children and adolescents (below 18 years of age). Consult your doctor before taking it.
The most common side effects of taking NIKOS 10MG TABLET are headache, dizziness, skin flushing, nausea, vomiting, weakness and rapid or forceful heartbeat. Consult your doctor if any of the symptoms worsen.
USES OF NIKOS 10MG TABLET
- To prevent and reduce painful signs of angina pectoris in adults
HOW NIKOS 10MG TABLET WORKS
NIKOS 10MG TABLET works by increasing blood flow through the heart vessels, leading to improved blood and oxygen supply to the heart muscle thus reducing the workload of the heart which results in reducing the frequency and severity of angina attacks.
DIRECTIONS FOR USE
Take NIKOS 10MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF NIKOS 10MG TABLET
COMMON
- headache
- dizziness
- flushed skin
- nausea
- vomiting
- weakness
- rapid, uneven or forceful heartbeat
- skin abscess (swollen, pus-filled lump within or below the skin surface)
- ulcers in mouth, small and large intestines or anal
UNCOMMON
- low blood pressure
- pus collection in genital, anal or other areas of digestive tract
- corneal ulcer (open sore in the corneal part of eye)
- conjunctival ulcer (type of inflammatory reaction of eye)
- conjunctivitis (pink eye)
RARE
- rash
- itching
- muscle pain not caused by exercise
Stop taking NIKOS 10MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- red, itchy, swollen or watery eyes including inflammation or ulcer in cornea or conjunctiva (parts of eye)
- signs of ulcers in mouth, stomach, large and small intestine or anus such as blood in stools, vomit, fistula (abnormal opening between organs), abscess (pus collection at infected site) and weight loss
- signs of diverticular disease (infected colon) such as ulcers in the skin, genital tract and nasal passages or around a stoma (artificial opening for waste removal)
HOW TO MANAGE SIDE EFFECTS
Nausea:
Take NIKOS 10MG TABLET with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. Consult your doctor if the symptom does not improve.
Vomiting:
Get adequate rest. Drink sufficient amount of fluids, especially water. Have small sips if you feel sick. Eat when you feel hungry. Do not take any medicine for vomiting without asking your doctor. Consult your doctor if the symptom gets worse.
Headache:
Drink ample amount of water. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.
Dizziness:
Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid smoking cigarettes and drinking alcohol. Consult your doctor if the symptom does not improve.
WARNING & PRECAUTIONS
PREGNANCY
NIKOS 10MG TABLET is not recommended for use in pregnant women. Consult your doctor before taking NIKOS 10MG TABLET.
BREASTFEEDING
NIKOS 10MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking NIKOS 10MG TABLET.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you feel dizzy or weak after taking NIKOS 10MG TABLET.
ALCOHOL
Avoid consumption of alcohol while taking NIKOS 10MG TABLET because it might further lower your blood pressure.
KIDNEY
NIKOS 10MG TABLET should be taken with caution in patients with kidney problems. Consult your doctor before taking NIKOS 10MG TABLET.
LIVER
NIKOS 10MG TABLET should be taken with caution in patients with liver disease such as fibrosis of liver and chronic liver disease. Consult your doctor before taking NIKOS 10MG TABLET.
ALLERGY
Do not take NIKOS 10MG TABLET if you are allergic to Nicorandil or any other ingredients of this medicine.
LUNGS
NIKOS 10MG TABLET is not recommended for use in patients having lung disease such as pulmonary oedema (fluid build-up in lungs). Consult your doctor before taking NIKOS 10MG TABLET.
HEART DISEASE
NIKOS 10MG TABLET is not recommended for use in patients with heart problems such as cardiogenic shock, left ventricular failure with low filling pressure and cardiac decompensation. It is used with caution in patients with heart failure. Consult your doctor before taking NIKOS 10MG TABLET.
OTHERS
NIKOS 10MG TABLET is not recommended for use if you have:
- signs of severe low blood pressure such as dizziness, light-headedness or feeling faint
- signs of low blood volume such as confusion, difficulty breathing or fast breathing, excessive sweating and loss of consciousness
Before taking NIKOS 10MG TABLET, inform your doctor if you have:
- low blood pressure
- signs of low blood potassium levels such as constipation, weakness, muscle damage
- have glucose-6 phosphate dehydrogenase deficiency (a genetic condition)
Use in pediatrics:
NIKOS 10MG TABLET is not recommended for use in children and adolescents (below 18 years of age). Consult your child’s doctor for advice.
Use in geriatrics:
NIKOS 10MG TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking NIKOS 10MG TABLET.
INTERACTIONS
A. Drug - Drug interactions:
Before taking NIKOS 10MG TABLET, inform your doctor if you are taking any of the following medicines:
- medicines used to treat erectile dysfunction (Ex. sildenafil, tadalafil, vardenafil)
- riociguat (used to treat high blood pressure in lung arteries)
- medicines used to treat inflammatory conditions such as corticosteroids (Ex. hydrocortisone, prednisolone)
- medicines used to relieve pain and inflammation (Ex. aspirin, ibuprofen)
- medicines used to treat heart conditions like high blood pressure, angina (Ex. enalapril, propranolol, valsartan and nitroglycerin)
- medicines that increase blood potassium levels (Ex. spironolactone)
- cyclosporin (used to prevent organ rejection after transplant)
- dapoxetine (used to treat premature ejaculation)
- medicines used to treat depression (Ex. nortriptyline, duloxetine)
Overdosage:
If you or anyone else accidentally take too much of NIKOS 10MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are weakness, dizziness, fast or uneven heartbeat.
SYNOPSIS
| Drug | : | Nicorandil |
| Pharmacological Category | : | Potassium channel activators |
| Therapeutic Indication | : | Angina pectoris |
| Dosage Forms | : | Tablet, Injection |
MORE INFORMATION
- Keep NIKOS 10MG TABLET out of reach of children
- Store at (2 - 8°C) in the refrigerator. Do not freeze
FAQs ABOUT NIKOS 10MG TABLET
Is it safe to use NIKOS 10MG TABLET in pregnant and breastfeeding women?
No, NIKOS 10MG TABLET is not recommended for use during pregnancy and in women with childbearing potential. It is also not recommended for use in breastfeeding women as it is not known whether it may pass in the breast milk. Consult your doctor for advice if you are planning to get pregnant.
Is NIKOS 10MG TABLET safe to use in children?
No, NIKOS 10MG TABLET is used for adults and not recommended for use in children and adolescents below 18 years of age. Child’s doctor will select a suitable alternative therapy for your child depending upon the condition.
What if I forget to take a dose of NIKOS 10MG TABLET?
If you miss or forget to take a dose of NIKOS 10MG TABLET, take it as soon as you remember. However, omit the missed dose if it is almost time for your next dose. Do not take the medicine twice to make up for a forgotten dose.
Can NIKOS 10MG TABLET be used in patients with liver problems?
NIKOS 10MG TABLET should be taken with caution in patients with liver problems such as fibrosis of liver and chronic liver disease. Your doctor may regularly monitor your liver function during treatment with NIKOS 10MG TABLET. Consult your doctor for advice before taking this medicine.
Is [GBNKEYWORD] safe to use in patients with heart problems?
NIKOS 10MG TABLET is not recommended for use in patients with heart problems such as cardiogenic shock, left ventricular failure with low filling pressure and cardiac decompensation. It is used with caution in patients with heart failure. Consult your doctor before taking NIKOS 10MG TABLET.
REFERENCES
1. KD. Tripathi. Antianginal and other Anti-ischemic Drugs. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 552.
2. Kevin Cheng, Khaldoon Alhumood, Fayez El Shaer, and Ranil De Silva. The Role of Nicorandil in the Management of Chronic Coronary Syndromes in the Gulf Region. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. December 2020. [Accessed on 6th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889547/
3. Jason M. Tarkin and Juan Carlos Kaski. Vasodilator Therapy: Nitrates and Nicorandil. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. June 2016. [Accessed on 6th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658472/
4. Dexcel Pharma Ltd. Electronic Medicines Compendium (EMC). [Revised in January 2022] [Accessed on 6th June 2022] https://www.medicines.org.uk/emc/files/pil.652.pdf
5. West-Coast Pharmaceutical Works Ltd. Nicovex-5 (Nicorandil Tablets BP 5 mg). [Accessed on 6th June 2022] https://westcoastin.com/product/nicorandil-tablets-5mg/
USEFUL DIAGNOSTIC TESTS
- Electrocardiogram (ECG)
- Coronary angiography
- Complete Blood Count (CBC)
AUTHOR DETAILS
Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 28 Nov 2022 | 10:53 AM(IST)
PRODUCT DETAILS
ALTERNATE BRANDS View All
₹0
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
