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INTRODUCTION
NEW MODLIP ASG 75MG is a combination of Aspirin and Atorvastatin which belongs to a group of medicines called Nonsteroidal anti-inflammatory drugs (NSAIDs) and Statins respectively. NEW MODLIP ASG 75MG is used to treat high levels of lipids (dyslipidemia) associated with atherosclerotic arterial disease with risk of myocardial infarction, stroke, or peripheral vascular disease. NEW MODLIP ASG 75MG lowers the bad cholesterol (LDL), triglycerides and raises the good cholesterol (HDL) levels in the body and also it decreases the formation of blood clots.
Aspirin is a non-steroidal anti-inflammatory drug prevents the platelets from clumping and clotting in arteries and improves blood flow to heart. Atorvastatin belongs to statins lowers cholesterol levels in the blood by blocking an enzyme that's needed for the liver to produce cholesterol.
Before taking NEW MODLIP ASG 75MG inform your doctor if you have bleeding disorder, liver, kidney, or heart conditions. Inform your physician if you are pregnant or breastfeeding. Tell your doctor about all previous medications you take before taking NEW MODLIP ASG 75MG. It is not suitable for use in children and adolescents under 16 years of age, unless specifically indicated by your doctor. The common side effects of NEW MODLIP ASG 75MG are constipation, headache, dizziness, abdominal pain, or nausea.
USES OF NEW MODLIP ASG 75MG
- prevent heart attack and stroke
HOW NEW MODLIP ASG 75MG WORKS
NEW MODLIP ASG 75MG helps to prevent heart attack and stroke, where atorvastatin works by slowing the production of cholesterol in the body to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body. Aspirin prevents the platelets from sticking together and decreases the formation of harmful blood clots.
DIRECTIONS FOR USE
Always take NEW MODLIP ASG 75MG as directed by your physician. Take this medicine with or without food, swallow the medicine as a whole and do not crush or chew the medicine. Do not stop taking NEW MODLIP ASG 75MG unless advised by your doctor.
SIDE EFFECTS OF NEW MODLIP ASG 75MG
COMMON
- constipation
- headache
- stomach pain
- flatulence
- indigestion
- nausea
- diarrhea
- joint pain, muscle or back pain
- signs of high blood sugar (dry mouth, fruity-smell breath, confusion)
- inflammation of nasal passage, nose bleeds
- pain in throat
- increased chance of bleeding
UNCOMMON
- loss of appetite
- weight gain
- decrease in blood sugar levels
- insomnia (sleep problems)
- dizziness
- tingling or numbness in fingers or toes
- altered taste sensation
- loss of memory
- blurred vision
- ringing in ear sensation
- skin rash, itching
- tiredness, weakness
- neck pain
- chest pain
- swollen ankles (edema)
- high body temperature
- runny nose
- trouble breathing
RARE
- tendon injury
- unusual bleeding or bruising, severe bleeding in stomach, intestine, or brain
- cholestasis (yellowing of skin or white of the eyes)
- asthma, cramps in lower respiratory tract
- abnormal heavy or prolonged menstrual periods
Stop taking NEW MODLIP ASG 75MG and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reactions (such as rash, swelling of the face, lips, mouth, or throat which can lead to difficulty in breathing or swallowing)
- severe skin reactions such as stevens johnson syndrome, erythema multiforme or lyell’s syndrome (skin rash, itching, blistering reddening of skin all over the body, peeling and swelling of the skin, swelling of mucous membrane)
- signs of unusual bleeding such as coughing up blood, blood in vomit or urine, or black tarry stools
- abnormal muscle breakdown known as rhabdomyolysis (identified by symptoms such as muscle weakness, tenderness, pain, fever, and red-brown discoloration of urine)
HOW TO MANAGE SIDE EFFECTS
Headache:
Rest and drink plenty of fluids. Apply a wet or cold cloth to forehead and rest in a quiet, comfortable, dark room.
Nausea:
Take this medicine with, or just after, a meal or snack and stick to simple meals and do not eat oil rich or spicy food.
Stomach pain:
Try to take rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach.
Constipation:
Take fiber rich foods in your diet such as fresh fruits, vegetables and whole grain cereals, and drink plenty of fluids. Exercise more regularly and stay active.
Diarrhea:
Drink plenty of fluids such as water, fruit juices or electrolytes to avoid dehydration in your body.
WARNING & PRECAUTIONS
PREGNANCY
NEW MODLIP ASG 75MG is not advisable during pregnancy as it may cause serious harm to your baby. Consult your doctor for advice.
BREASTFEEDING
It is not recommended for mothers who are breast-feeding as there is limited information on the use of NEW MODLIP ASG 75MG during breastfeeding. Consult your doctor before taking.
DRIVING AND USING MACHINES
Do not drive or handle any machines if you experience dizziness, decreased alertness, vision problems or sleepiness while taking NEW MODLIP ASG 75MG.
ALCOHOL
Consumption of alcohol is not recommended while taking this NEW MODLIP ASG 75MG as it can increase the risk of bleeding and prolongs the bleeding time.
KIDNEY
NEW MODLIP ASG 75MG is not recommended for use in patients with severe kidney disease. Consult your doctor for advice.
LIVER
NEW MODLIP ASG 75MG is not recommended for use in patients with severe liver disease and active liver disease. Consult your doctor for advice.
ALLERGY
Tell your doctor if you are allergic to Aspirin or Atorvastatin or any other inactive preparations of NEW MODLIP ASG 75MG.
LUNGS
NEW MODLIP ASG 75MG should be used with caution in patients with asthma or long-term respiratory diseases as it can induce asthma attacks or promotes bronchospasm (tightening of muscles in airways resulting in shortness of breath).
HEART DISEASE
NEW MODLIP ASG 75MG should be used with caution in patients with any heart disease or problems. Consult your doctor for advice.
OTHERS
Before taking NEW MODLIP ASG 75MG, inform your doctor if you have:
- hypoprothrombinaemia, haemophilia (problem in blood clotting)
- history of peptic ulceration
- history of hereditary muscular disorders
- history of stroke with bleeding into the brain or fluid buildup in brain
- various conditions such as diabetes, hypertension, hypothyroidism and gout
Use in pediatrics:
NEW MODLIP ASG 75MG is not recommended for use in children less than 16 years of age. Consult your doctor for advice.
Use in geriatrics:
NEW MODLIP ASG 75MG should be used with caution in elderly patients above 65 years of age due to increased risk of side effects. Consult your doctor for advice.
INTERACTIONS
A. Drug-Drug interactions:
Before taking NEW MODLIP ASG 75MG inform to your doctor, if you are taking,
- ciclosporin (used to suppress immune activity)
- telithromycin, clarithromycin, fusidic acid (treats bacterial infection)
- ketoconazole, voriconazole, posaconazole (treats fungal infections)
- ritonavir, lopinavir, atazanavir (treats HIV infection)
- letermovir (used to prevent cytomegalovirus)
- stiripentol, phenytoin and sodium valproate (treats epilepsy)
- gemfibrozil, ezetimibe (treats cholesterol)
- telaprevir, boceprevir (treats hepatitis C virus)
- amlodipine, diltiazem (treats high blood pressure)
- digoxin, verapamil, and amiodarone (treats irregular heartbeat)
- cimetidine (treat heartburn and peptic ulcer)
- colchicine, probenecid (treats gout)
- non-steroidal anti-inflammatory drugs such as phenazone, ibuprofen (treats pain and fever)
- warfarin, heparin (treats blood clot)
- st. john’s wort (treats depression)
- oral contraceptives
- acetazolamide (treats gout)
- insulin, glibenclamide (treats diabetes)
- ACE inhibitor drugs such as lisinopril, enalapril and diuretics such as furosemide, hydrochlorothiazide (used to treat high blood pressure)
- methotrexate (treats cancer)
- lithium (treats mania or depression)
- sertraline or paroxetine (treats depression)
B. Drug-Food interactions:
While taking NEW MODLIP ASG 75MG, avoid taking large quantities of grapefruit juice as it can alter the effects of this medicine resulting in undesired therapeutic outcome.
Overdosage:
If you or anyone else accidentally take too much of NEW MODLIP ASG 75MG, consult your doctor immediately. Overdosage of NEW MODLIP ASG 75MG can cause undesirable effects such as headache, dizziness, confusion, hearing problems, ringing in ears, rapid breathing than normal, increased sweating, seizures and low blood sugar.
SYNOPSIS
| Drug | : | Aspirin and Atorvastatin |
| Pharmacological Category | : | Nonsteroidal anti-inflammatory drugs (NSAIDs) and Statins |
| Therapeutic Indication | : | Prevents Heart attack and Stroke |
| Dosage Forms | : | Capsule, Tablet |
MORE INFORMATION
- Keep out of reach of children
- Store at normal room temperature
FAQs ABOUT NEW MODLIP ASG 75MG
Can NEW MODLIP ASG 75MG cause muscle pain?
Yes, NEW MODLIP ASG 75MG may cause muscle pain, weakness, and tenderness in some individuals, it should be used with caution in elderly patients. NEW MODLIP ASG 75MG can lead to abnormal muscle breakdown known as rhabdomyolysis which can be identified by symptoms such as red-brown discoloration of urine, high fever. Consult your doctor immediately, if left untreated it can lead to severe kidney problems.
Can I drink alcohol while taking NEW MODLIP ASG 75MG?
No, avoid drinking alcohol while taking NEW MODLIP ASG 75MG as it may increase the risk of bleeding in stomach or delays bleeding time. Drinking alcohol also worsens the condition of the patient resulting in increased risk of heart attack or stroke.
Is NEW MODLIP ASG 75MG safe to use in lung disease patients?
NEW MODLIP ASG 75MG should be used with caution in patients having asthma or other chronic respiratory problems as it can induce asthma attacks or causing difficulty in breathing due to obstruction of airways. Also, NEW MODLIP ASG 75MG should be used with caution in patients with nasal polyps and allergic rhinitis.
What foods should I avoid while taking NEW MODLIP ASG 75MG?
While taking NEW MODLIP ASG 75MG avoid eating foods high in fat or cholesterols such as fried or processed foods, grapefruit juice, dairy products, and red meat which can lead to poor therapeutic outcome to treat disease.
Can I take NEW MODLIP ASG 75MG with hypertension drugs?
NEW MODLIP ASG 75MG should be used with caution in patients with high blood pressure as it can increase the risk of high blood pressure or alter the effectiveness of anti-hypertensive medicine (such as lisinopril, ramipril, chlorthalidone) leading to poor therapeutic outcome in managing high blood pressure. Before taking NEW MODLIP ASG 75MG inform your doctor about previous medication history.
REFERENCES
1. KD. Tripathi. Drugs affecting coagulation, bleeding and thrombosis & Hypolipidaemic Drugs and Plasma Expanders. Essentials of medical pharmacology. Seventh edition. 2013. Page – 629 & 637.
2. Dhruv Mahtta, David J. Ramsey and Mahmoud Al Rifai. Evaluation of Aspirin and Statin Therapy Use and Adherence in Patients with Premature Atherosclerotic Cardiovascular Disease. Aug 20, 2020. [Accessed on Aug 21, 2021] https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2769571
3. Charles H Hennekens, Danielle Hollar and Arthur S Agatston. Aspirin and Statins to Decrease Risks of Cardiovascular Disease – The Need for Wider Utilization. [Accessed on Aug 21, 2021] https://www.uscjournal.com/articles/aspirin-and-statins-decrease-risks-cardiovascular-disease-need-wider-utilization-0
4. Torrent Pharmaceuticals LTD. May 2015. [Accessed on Aug 21, 2021] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2444.pdf
5. CP Pharmaceuticals Ltd, Electronic Medicines Compendium (EMC). [Revised in March 2020] [Accessed Aug 21, 2021] https://www.medicines.org.uk/emc/files/pil.2348.pdf
6. Accord-UK Limited, Electronic Medicines Compendium (EMC). [Revised in March 2021] [Accessed Aug 21, 2021] https://www.medicines.org.uk/emc/files/pil.2408.pdf
USEFUL DIAGNOSTIC TESTS
- Lipid profile
- Kidney function test
PRODUCT DETAILS
ALTERNATE BRANDS
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