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INTRODUCTION
NEPATOP EYE DROPS contains Nepafenac which belongs to the group of medicines called Ophthalmic anti-inflammatory agents. It is used in adults to treat and prevent eye pain and eye inflammation following cataract surgery. It can also be used to prevent the risk of macular edema (swelling at the back of the eye) following cataract surgery in diabetic patients.
NEPATOP EYE DROPS is for ophthalmic use only. Use NEPATOP EYE DROPS as instructed by the physician to achieve better results. Avoid wearing contact lenses after undergoing cataract surgery. Your doctor will advise you when you can use contact lenses again.
Before using NEPATOP EYE DROPS inform your doctor if you have diabetes, arthritis or bleeding problems. You must also inform your doctor if you have any other eye problems apart from inflammation (such as eye infections, glaucoma etc.).
NEPATOP EYE DROPS is not recommended for use in pregnant women unless considered necessary by the physician. Women of child-bearing potential must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with NEPATOP EYE DROPS.
NEPATOP EYE DROPS can be used in breastfeeding women if prescribed by the doctor. The most common side effects of using NEPATOP EYE DROPS are visual disturbances, sensation of a foreign body in the eye and eye irritation. Contact your doctor if they trouble you.
USES OF NEPATOP EYE DROPS
It is used in adults to:
- Treat and prevent eye pain and inflammation following cataract surgery
- Prevent the risk of macular oedema following cataract surgery in diabetic patients
HOW NEPATOP EYE DROPS WORKS
NEPATOP EYE DROPS is an analgesic medication. It works by blocking the release of certain chemical messengers (prostaglandins) in the eye that causes inflammation, pain and swelling. As a result, it provides relief from post-surgical eye pain, inflammation and swelling.
DIRECTIONS FOR USE
Use NEPATOP EYE DROPS as advised by your physician. It is for ophthalmic use only.
Wash your hands before application. Tilt your head slightly backwards and place the tip of the container close to your eyes. Gently pull your lower eyelid and instill few drops of the medicine as directed by your physician.
Close your eyes and gently press the inner corner of your eye for 2 minutes. Repeat the same for the other eye if required.
Do not touch the tip of the container with your eyes, eyelids or areas around your eyes or fingers, to avoid contamination.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition.
SIDE EFFECTS OF NEPATOP EYE DROPS
COMMON
- visual disturbances
- sensation of foreign body in the eye
- sticky sensation
UNCOMMON
- eye discomfort
- eyelid crusting or drooping
RARE
- dry eye, eyelid swelling
- itchy eye
- eye discharge
- increased tear production
- dizziness, headache
Stop using NEPATOP EYE DROPS and contact your doctor immediately if you experience any of the following side effects:
- severe eye pain with redness (inflammation of iris)
HOW TO MANAGE SIDE EFFECTS
Eye discomfort:
Wash your eyes with plain cold water. Place an ice pack on your eye to ease the irritation. Avoid straining your eyes by looking at mobile phones, laptops, or television. Wear protective eyeglasses while going outdoors. If irritation still persists, contact your doctor.
Visual Disturbances:
Close your eyes and relax. Do not strain your eyes by looking at mobile phones, laptops, or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience problems in your vision for a prolonged period.
WARNING & PRECAUTIONS
PREGNANCY
NEPATOP EYE DROPS is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, inform your doctor before using NEPATOP EYE DROPS if you are pregnant, think you may be pregnant or planning to have a baby. Women of child-bearing potential must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with NEPATOP EYE DROPS.
BREASTFEEDING
NEPATOP EYE DROPS can be used in breastfeeding women if prescribed by the doctor. Consult your doctor for advice.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you experience blurred vision after using NEPATOP EYE DROPS. Wait, until your vision becomes clear.
ALLERGY
Do not use NEPATOP EYE DROPS if you are allergic to nepafenac or to other non-steroidal anti-inflammatory medicines (such as ibuprofen, aspirin, piroxicam, ketoprofen, diclofenac).
LUNGS
NEPATOP EYE DROPS is not recommended for use in patients who previously developed asthma while using any non-steroidal anti-inflammatory drugs. Therefore, consult your doctor before application.
OTHERS
NEPATOP EYE DROPS is not recommended for use if you:
- had previously experienced any skin allergy or intense inflammation in your nose following the use of any pain relieving medicines
Before using NEPATOP EYE DROPS, inform your doctor if you:
- bruise easily or have any bleeding problems
- have an eye infection or any other eye disorders
- have diabetes
- have rheumatoid arthritis (inflammation of joints)
- have had repeated eye surgery within a short period of time
Use in pediatrics:
NEPATOP EYE DROPS is generally not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before application.
Use in geriatrics:
NEPATOP EYE DROPS should be used with caution in elderly patients (aged 65 years and above). Therefore, consult your doctor before application.
INTERACTIONS
A. Drug-Drug interactions:
Before using NEPATOP EYE DROPS, inform your doctor if you are taking any of the following medicines such as:
- other eye drops for the treatment of glaucoma (Ex. timolol)
- medicines used to reduce blood clotting (Ex. warfarin)
- other non-steroidal anti-inflammatory drugs to reduce pain (Ex. aspirin, ibuprofen, ketoprofen, piroxicam, diclofenac)
- topical steroids on the eye (Ex. hydrocortisone)
Overdosage:
If you or anyone else accidentally used more NEPATOP EYE DROPS, rinse your eye with warm water. If still irritation persists, consult your doctor.
SYNOPSIS
| Drug | : | Nepafenac |
| Pharmacological Category | : | Nonsteroidal anti-inflammatory drugs (NSAIDs) |
| Therapeutic Indication | : | Post-operative eye pain, inflammation and swelling |
| Dosage Forms | : | Eye drops, Ophthalmic suspension |
MORE INFORMATION
- Keep NEPATOP EYE DROPS out of reach of children
- Store NEPATOP EYE DROPS at room temperature
FAQs ABOUT NEPATOP EYE DROPS
Is it safe to use NEPATOP EYE DROPS in infants?
NEPATOP EYE DROPS is generally not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before taking it.
Is NEPATOP EYE DROPS NSAIDs?
Yes NEPATOP EYE DROPS is a nonsteroidal anti-inflammatory drug (NSAID). It reduces pain and inflammation in the eyes. It is used to reduce pain and swelling after cataract surgery.
Can NEPATOP EYE DROPS be used in breastfeeding women?
NEPATOP EYE DROPS should be used with caution in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.
What is the use of NEPATOP EYE DROPS?
NEPATOP EYE DROPS is used to prevent and relieve eye pain and inflammation and to reduce the risk of macular edema (swelling in the back of the eye) following cataract surgery on the eye in diabetic patients.
Is NEPATOP EYE DROPS causing blurred vision?
Yes. NEPATOP EYE DROPS causes vision to be blurred for a time just after using it. Do not drive or use a machine until your vision is clear.
Can I use NEPATOP EYE DROPS, if I have asthma?
NEPATOP EYE DROPS is not recommended for use in patients with asthma. Consult your doctor before using.
How do NEPATOP EYE DROPS work?
NEPATOP EYE DROPS is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling) in the eye.
Can the use of NEPATOP EYE DROPS cause blurred vision?
Yes. NEPATOP EYE DROPS may cause visual disturbances after application in some individuals, although not everybody gets the,. If your vision becomes blur, close your eyes for some time and rest. Do not strain your eyes by looking at mobile phones, laptops, or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
Can I use other eye medicines while using NEPATOP EYE DROPS?
Avoid concomittant use of any eye medicines while using NEPATOP EYE DROPS without consulting your doctor.
How to use NEPATOP EYE DROPS?
Use NEPATOP EYE DROPS as advised by your physician. It is for ophthalmic use only. Instill few drops of the medicine into the affected eye(s). Close your eyes and press the corner of your eye with your finger for a minute. Repeat the same for the other eye if required.
What is the use of NEPATOP EYE DROPS?
NEPATOP EYE DROPS is a prescription medicine used to treat and prevent eye pain and eye inflammation following cataract surgery. It can also be used to prevent the risk of macular edema (swelling at the back of the eye) following cataract surgery in diabetic patients.
How long does it take for [GBNKRYWORD] to work?
It may take around 10-15 minutes for NEPATOP EYE DROPS to start showing its effects. However, this period may vary from person-to-person depending upon the dose that is administered.
What are the side effects of NEPATOP EYE DROPS?
NEPATOP EYE DROPS is generally safe and well tolerated. It may cause visual disturbances, eye discomfort, sensation of a foreign body in the eye and eye irritation in some individuals. Contact your doctor if they trouble you.
Can I use NEPATOP EYE DROPS while wearing contact lenses?
No. Avoid wearing contact lenses after cataract surgery. Your doctor will decide when you should wear contact lenses once again.
Can I stop using NEPATOP EYE DROPS without consulting my doctor?
Do not stop using NEPATOP EYE DROPS without consulting your doctor, as the symptoms may reappear once again. If you think that you are feeling better or if you wish to stop using NEPATOP EYE DROPS, contact your doctor for advice.
Can I drive or ride a bike after using NEPATOP EYE DROPS?
Do not drive if you experience blurred vision after using NEPATOP EYE DROPS.
What if I miss a dose of NEPATOP EYE DROPS?
If you missed a dose of NEPATOP EYE DROPS, apply it as soon as you remember. However, if it is time for next dose, skip the missed dose and use the regular dose. Do not use a double dose of NEPATOP EYE DROPS to compensate the missed dose.
How NEPATOP EYE DROPS works?
NEPATOP EYE DROPS is an analgesic medication. It works by blocking the release of certain chemical messengers (prostaglandins) in the eye that causes inflammation, pain and swelling. As a result, it provides relief from post-surgical eye pain, inflammation and swelling.
REFERENCES
1. Jeffrey D. Henderer and Christopher J. Rapuano. Ocular Pharmacology. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical 2018 Page – 1251-1270.
2. Bardoloi, Narayan, Sarkar, Sandip, Burgute, Pankaj Suresh, Deb, Amit Kumar, Dholkawala, Roshni, Aggarwal, Priyal, Gokhale, Tanmay. Comparison of once daily dose of 0.3% nepafenac alone and three times dose of 0.1% nepafenac alone in pain and inflammation control after phacoemulsification. Indian Journal of Ophthalmology. March 2022 [Accessed on 8th November 2022] https://journals.lww.com/ijo/Fulltext/2022/03000/Comparison_of_once_daily_dose_of_0_3__nepafenac.21.aspx
3. Satish S. Modi, MD, FRCSC, CPI, Robert P. Lehmann, MD, Thomas R. Walters, MD, Raymond Fong, MD,William C. Christie, MD, Lawrence Roel, MD, PhD, David Nethery, MD, Dana Sager, MS,Alexis Tsorbatzoglou, MD, PhD, Bo Philipson, MD, PhD, Carlo E. Traverso, MD, Harvey Reiser, MD. Once-daily nepafenac ophthalmic suspension0.3% to prevent and treat ocular inflammation and pain after cataract surgery: Phase 3 study. Journal of Cataract and Refractive Surgery. December 2013. [Accessed on 8th November 2022] https://www.researchgate.net/publication/259351879_Once-daily_nepafenac_ophthalmic_suspension_03_to_prevent_and_treat_ocular_inflammation_and_pain_after_cataract_surgery_Phase_3_study
4. Alcon Laboratories, Inc. 2005, U.S. Food & Drug Administration. [Revised in June 2011]. [Accessed on 8th November 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021862s008lbl.pdf
5. Novartis Pharmaceuticals UK Ltd. Electronic Medicines Compendium (EMC). [Revised in October 2021]. [Accessed on 8th November 2022] https://www.medicines.org.uk/emc/files/pil.6549.pdf
6. Novartis Pharmaceuticals UK Ltd. Electronic Medicines Compendium (EMC). [Revised in October 2021]. [Accessed on 8th November 2022] https://www.medicines.org.uk/emc/files/pil.2675.pdf
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