Neotrexate 50mg Injection 2ml

Cancer/Oncology Rx required

Best Price*  ₹ 45.68
MRP ₹50.76
(Inclusive of all taxes) Get the best price on this product on orders above Rs. 1250 * Mfr: Glaxosmithkline Pharmaceuticals Ltd * Country of Origin: NA


  • NEOTREXATE 50MG contains Methotrexate which is an anti-metabolite medicine (medicine which affects how the body’s cells grow) and immunosuppressant (medicine which reduces the activity of the immune system)
Therapeutic Uses
Warning & Precautions
Directions & For Use
Side Effects
More Information

What NEOTREXATE 50MG is used for?

NEOTREXATE 50MG is used to treat,

  • certain types of cancer such as breast cancer
  • severe psoriasis (a skin disease with thickened patches of inflamed red skin, often covered by silvery scales)

Talk to Doctor

Pregnancy & Breast Feeding

Children & Adolescents

Driving & Using Machines

Talk to your doctor before taking this medicine, if you:

  • are allergic to Methotrexate or any of the other ingredients of NEOTREXATE 50MG 
  • have significant kidney or liver problems
  • have been told you have a blood disorder such as low levels of white blood cells, red blood cells (anaemia) or platelets
  • have any infection or weak immune system
  • have a stomach ulcer or ulcerative colitis (inflammation and ulceration of the gut)
  • have a medical condition which causes a buildup of fluid in the lining of your lungs or in your abdomen (the fluid will need to be drained before NEOTREXATE 50MG treatment is started)
  • are undergoing radiotherapy (risk of tissue and bone damage may be increased)


  • Tell your doctor if you are pregnant, trying to become pregnant or breast-feeding before this medicine is used. This medicine must not be used during pregnancy
  • Mothers should not breast-feed while treating with NEOTREXATE 50MG 
  • Due to the risk of birth defects, conception should be avoided during NEOTREXATE 50MG treatment and for at least 6 months after treatment is stopped. Ask your doctor for advice before taking any medicine
  • This medicine can be used to treat children with severe psoriasis, but should not be used in those under 3 years of age
  • Do not drive or use machines if you experience any side effect (e.g. dizziness, drowsiness or blurred vision) which may lessen your ability to do so

Special care is needed if you are taking/using other medicines as some could interact with methotrexate, for example:

  • non-steroidal anti-inflammatory medicines e.g. ibuprofen (medicines taken for pain relief)
  • aspirin or similar medicines (known as salicylates)
  • omeprazole, esomeprazole and pantoprazole (medicines used to reduce the production of stomach acid)
  • diuretics (water tablets)
  • medicines used for diabetes (including insulin and tablets)
  • antibiotics such as penicillins, sulphonamides, co-trimoxazole, trimethoprim, tetracycline, chloramphenicol and para-aminobenzoic acid
  • phenytoin (medicine often used to treat epilepsy)
  • vitamin supplements containing folic acid
  • probenecid (medicine used to treat gout)
  • nitrous oxide (used for general anaesthesia and pain relief)
  • live virus vaccines
  • mercaptopurine (medicine used in the treatment of blood cell cancer)
  • theophylline (medicine used in the treatment of asthma)
  • This medicine may be given by injection into a vein (intravenous injection), into muscle (intramuscular injection), into an artery (intraarterial injection) or into the spine (intrathecal injection)
  • It may also be given by infusion (drip) into a vein. It may be diluted before it is given. Of the presentations available (see section 6) only the 50 mg/2 ml is suitable for intrathecal injection
  • The dose of medicine given to you will depend on the disease being treated, your medical condition, your age, your size and how well your kidneys are working
Very Rare

Like all medicine, this medicine can cause side effects, although not everybody gets them.

  • severe allergic reaction - you may experience a sudden itchy rash (hives), swelling of the hands, feet, ankles, face, lips, mouth or throat (which may cause difficulty in swallowing or breathing), and you may feel you are going to faint
  • inflammation of the lung with breathlessness
  • symptoms of an infection e.g. fever, chills, pain , sore throat
  • unexpected bleeding e.g. bleeding gums, blood in the urine or in vomit, or the appearance of unexpected bruises or broken blood vessels (broken veins)
  • black tarry stools
  • skin rashes or blistering to the surfaces of the eyes, nose, vagina or anus (back passage), acne, shingles (herpes zoster)
  • weakness in the legs that spreads to the upper limbs and the face, which may result in paralysis
  • abdominal pain, fatty stools, vomiting, diarrhoea
  • chest pain (which may be due to heart or lung problems)
  • low blood pressure (you may feel faint)
  • fits
  • blurred vision, dizziness
  • difficulty/inability to talk, muscle weakness
  • you may feel the need to drink more than usual (diabetes)
  • abnormally easily broken bones (osteoporosis)
  • pain or redness of the blood vessels (vasculitis)
  • increased sensitivity to sunlight
  • yellowing of the skin and whites of the eyes (jaundice)
  • you may need to pass urine more often than normal, which may be painful (cystitis)
  • headaches, drowsiness
  • irregular periods in women (periods may stop completely)
  • hair loss
  • effects on learning and memory, mood alterations
  • ringing in the ears
  • joint and muscle pain
  • blood clot which causes pain, swelling or redness (cerebral, deep vein, retinal vein or arterial vein)
  • difficulty with bending your head down
  • irritability and confusion





Additional Information


  • Keep out of reach of children
  • This medicine must not be used after the expiry date
  • The vials should be kept in the outer carton, to protect from light, and stored at (15-25°C)
  • The vials should not be frozen
  • Unused portions of opened vials must not be stored for later use
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