Neomit 2mg Injection 4ml

Vomitting/Emesis Rx required
OUT OF STOCK

Best Price*  ₹ 12.00
MRP ₹15.00
(Inclusive of all taxes) * Mkt: Neon Laboratories Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

NEOMIT 2MG contains Ondansetron which belongs to a group of medicines called anti-emetics, which help to stop feeling or being sick. It is indicated to prevent and treat nausea and vomiting induced by cytotoxic therapy and radiotherapy and post-operative nausea and vomiting. This medicine works by blocking the action of serotonin levels in the brain which causes nausea and vomiting during chemotherapy or any other surgery.

Cytotoxic chemotherapy triggers the release of serotonin from the enterochromaffin cells of the small intestine. The released serotonins stimulate the vagal afferents through the 5-HT3 receptors and initiate the vomiting reflex. Ondansetron is a selective 5-HT3 receptor antagonist which blocks serotonin, both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone. It works by blocking serotonin in the brain which causes nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

Before receiving NEOMIT 2MG, tell your doctor if you have liver, kidney or heart problems, pregnant women and breastfeeding mothers. Your doctor will administer the right dose depends on your child’s age and body weight. The common side effects are headache, constipation and dizziness.

USES OF NEOMIT 2MG

  • Cancer chemotherapy-induced nausea and vomiting
  • Postoperative nausea and/or vomiting

HOW NEOMIT 2MG WORKS

NEOMIT 2MG is a selective 5-HT3-receptor antagonist which blocks serotonin, both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone. It works by blocking serotonin in the brain which causes nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

DIRECTIONS FOR USE

NEOMIT 2MG should be only given by a doctor or nurse. Your healthcare provider will administer as intravenous injection (into a vein) or, after dilution, as intravenous infusion.

SIDE EFFECTS OF NEOMIT 2MG

COMMON

  • headache
  • sensation of flushing and warmth
  • constipation
  • pain, redness, burning at injection site

RARE

  • dizziness during rapid intravenous administration
  • skin rash
  • transient visual disturbances (blurred vision)
  • chest pain
  • temporary loss of vision

HOW TO MANAGE SIDE EFFECTS

Headache:

Rest and drink plenty of fluids.

Constipation:

Add fruits, vegetables whole grains and other high-fiber foods to your normal diet.

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

WARNING & PRECAUTIONS

PREGNANCY

NEOMIT 2MG is not recommended in the first trimester of pregnancy unless necessary. Consult your doctor for advice.

BREASTFEEDING

NEOMIT 2MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

This medicine has no or negligible effect on the ability to drive or use machines.

LIVER

NEOMIT 2MG should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.

ALLERGY

Tell if you are allergic (hypersensitive) to Ondansetron.

HEART DISEASE

NEOMIT 2MG should be used with caution in patients suffering from uneven heartbeat or any other active heart diseases. Consult your doctor for advice.

OTHERS

Inform your doctor if you have or had,

  • blockage in your gut or suffer from severe constipation
  • surgery to the adenoids or tonsils
  • problems with the levels of salts in blood like potassium and magnesium

INTERACTIONS

Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following,

  • apomorphine (used to treat Parkinson’s Disease)
  • phenytoin, carbamazepine (used to treat epilepsy)
  • rifampicin, erythromycin (an antibiotic)
  • tramadol (used to treat pain)
  • haloperidol, methadone
  • medicines used to treat heart problems such as abnormal heart beats (anti-arrhythmics)
  • fluoxetine, paroxetine, sertraline (used to treat depression)
  • anthracyclines
  • ketoconazole (used to treat fungal infection)

SYNOPSIS

Drug :   Ondansetron
Pharmacological Category :   Selective 5-HT3 Receptor Antagonist
Therapeutic Indication :   Cancer chemotherapy-induced nausea and vomiting, Postoperative nausea and/or vomiting
Dosage Forms :   Tablet, Injection, Syrup

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT NEOMIT 2MG

Can NEOMIT 2MG be given in children?

Your doctor will administer the right dose depends on your child’s age and body weight.

Can use NEOMIT 2MG during pregnancy?

It is not recommended in the first trimester of pregnancy unless necessary. Consult your doctor for advice.

REFERENCES

1. KD Tripathi MD. 5-HT, its antagonists and drug therapy of migraine. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 171.

2. Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page - 1341-1342.

3. Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. Page – 285.

4. Parker, Samantha E. Van Bennekom, Carla, Anderka, Marlene, Mitchell, Allen A. Ondansetron for Treatment of Nausea and Vomiting of Pregnancy and the Risk of Specific Birth Defects. Aug 2018, vol-132; [Accessed Jan 5, 2021] https://journals.lww.com/greenjournal/Fulltext/2018/08000/Ondansetron_for_Treatment_of_Nausea_and_Vomiting.16.aspx

6. Siegfried Hameln GmbH (Germany); [Revised Sep, 2019] [Accessed Jan 6, 2021] https://mri.cts-mrp.eu/human/downloads/DE_H_0806_001_FinalPI_2of2.pdf

7. Mylan Pharmaceuticals ULC; [Revised March 19, 2015] [Accessed Jan 6, 2021] https://pdf.hres.ca/dpd_pm/00029957.PDF

8. GlaxoSmithKline. May, 2010. U.S. Food & Drug Administration [Accessed Jan 6, 2021] https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/020007s040,020403s018lbl.pdf

9. Fresenius Kabi Australia Pty Limited. Nov 28, 2012; [Revised May 28, 2010] [Accessed Jan 6, 2021] https://www.fresenius-kabi.com/au/documents/Ondansetron__PI.pdf

PRODUCT DETAILS

    Net Qty
    1
    Ingredient
    ONDANSETRON 2MG
    Hsn Code
    30049035
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