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NEO MERCAZOLE 20mg Tablet 120's
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INTRODUCTION
NEO MERCAZOLE 20MG TABLET contains Carbimazole which belongs to the group of medicines called Antithyroid agents. It is used in adults and children to reduce the formation of thyroid hormones in hyperthyroidism (an over-active thyroid gland), to restore the normal function of the thyroid before its partial removal by surgery and together with other treatments for overactive thyroid.
Your doctor may ask you for occasional blood, liver tests to determine how you are responding to treatment. NEO MERCAZOLE 20MG TABLET is not recommended to use in patients with severe liver, blood disorders or history of inflammation of the pancreas (acute pancreatitis).
Before taking NEO MERCAZOLE 20MG TABLET inform your doctor if you have bone marrow depression, mild or moderate liver problems, swelling in your neck called an intrathoracic goitre or intolerant to certain sugars. NEO MERCAZOLE 20MG TABLET should be used with caution in pregnant women as it can harm the unborn baby. It is not recommended for use in breast-feeding women. Consult your doctor before taking.
NEO MERCAZOLE 20MG TABLET is not recommended for use in children below 2 years of age and should be used with caution in elderly patients above 65 years of age. Contact your doctor if you experience any unusual symptoms.
USES OF NEO MERCAZOLE 20MG TABLET
- it is used to treat hyperthyroidism
HOW NEO MERCAZOLE 20MG TABLET WORKS
NEO MERCAZOLE 20MG TABLET works by decreasing the uptake and concentration of inorganic iodine by thyroid, it also reduces the formation of thyroxine, hence reducing the production of the thyroid hormones (T3 and T4).
DIRECTIONS FOR USE
Take NEO MERCAZOLE 20MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
SIDE EFFECTS OF NEO MERCAZOLE 20MG TABLET
RARE
Stop taking NEO MERCAZOLE 20MG TABLET and consult your doctor immediately if you experience any of the following side effects:
- if you develop fever or abdominal pain, which may be signs of inflammation of the pancreas (acute pancreatitis)
- weakness, pale skin, rapid heartbeat, shortness of breath (pancytopenia/aplastic anaemia)
- easy or excessive bruising, prolonged bleeding from cuts, blood in urine or stools (thrombocytopaenia)
- bone morrow depression which causes a reduction in the number of blood cells and reduces the ability to fight infection
WARNING & PRECAUTIONS
PREGNANCY
NEO MERCAZOLE 20MG TABLET should be used with caution in pregnant women or women planning to have a baby. It will be given to you only if the potential benefit outweighs the potential risk to you and your unborn baby.
Use reliable contraception from the time you start treatment and during treatment to avoid pregnancy. Consult your doctor before taking it.
BREASTFEEDING
NEO MERCAZOLE 20MG TABLET is generally not recommended for use in breastfeeding women as it may pass through breast milk. Consult your doctor before taking it.
DRIVING AND USING MACHINES
Do not drive or operate any machines after taking NEO MERCAZOLE 20MG TABLET until you are sure your judgement and coordination are not affected.
LIVER
NEO MERCAZOLE 20MG TABLET is not recommended for use in patients with severe liver disease.
It should be used with caution in patients with mild to moderate liver disease. Consult your doctor before taking it.
ALLERGY
Do not take NEO MERCAZOLE 20MG TABLET if you are allergic to Carbimazole or any other ingredients of this medicine.
OTHERS
NEO MERCAZOLE 20MG TABLET is not recommended for use if you:
- have severe blood disorders
- have history of inflammation of the pancreas (acute pancreatitis)
Before taking NEO MERCAZOLE 20MG TABLET inform your doctor if you:
- have bone marrow depression
- have swelling in your neck called an intrathoracic goitre
- are intolerant to certain sugars
Use in paediatrics:
NEO MERCAZOLE 20MG TABLET is not recommended for use in children below 2 years of age. Consult your doctor before taking it.
Use in geriatrics:
NEO MERCAZOLE 20MG TABLET should be used with caution in elderly patients (aged 65 years and above) due to high risk of side effects. Consult your doctor before taking it.
INTERACTIONS
A. Drug-Drug interactions:
Before taking NEO MERCAZOLE 20MG TABLET, inform your doctor if you are taking any of the following medicine:
- anticoagulants (used to thin blood or stop clotting) (Ex. warfarin)
- to treat asthma or breathing problems (Ex. theophylline)
- steroids (Ex. prednisolone) to treat allergies
- antibiotic (Ex. erythromycin) to treat bacterial infections
- to treat heart failure (Ex. digitalis)
- to treat high blood pressure (Ex. atenolol)
Overdosage:
If you take or anyone else accidentally takes too much of NEO MERCAZOLE 20MG TABLET, consult your doctor immediately or visit the nearest hospital.
SYNOPSIS
| Drug | : | Carbimazole |
| Pharmacological Category | : | Antithyroid agents |
| Therapeutic Indication | : | Hyperthyroidism |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep NEO MERCAZOLE 20MG TABLET out of reach of children
- Store at a temperature, not more than 25°C
FAQs ABOUT NEO MERCAZOLE 20MG TABLET
Can I take NEO MERCAZOLE 20MG TABLET if I have liver problems?
NEO MERCAZOLE 20MG TABLET is not recommended for use in patients with severe liver disease. It should be used with caution in patients with mild to moderate liver disease. Consult your doctor before taking it.
What is NEO MERCAZOLE 20MG TABLET used for?
NEO MERCAZOLE 20MG TABLET is used in adults and children to reduce the formation of thyroid hormones in hyperthyroidism (an over-active thyroid gland), to restore the normal function of the thyroid before its partial removal by surgery and together with other treatments for overactive thyroid.
Can NEO MERCAZOLE 20MG TABLET make me tired?
Yes, NEO MERCAZOLE 20MG TABLET can make you feel tired, worried and develop menstrual problems. Consult your doctor if for more information if you experience any of these side effects.
Can NEO MERCAZOLE 20MG TABLET cause hair loss?
NEO MERCAZOLE 20MG TABLET may rarely cause hair loss but not in everyone. But this usually resolves, and hair growth goes back to normal withing a short time. Consult your doctor for more information.
How does NEO MERCAZOLE 20MG TABLET work?
NEO MERCAZOLE 20MG TABLET works by decreases the uptake and concentration of inorganic iodine by thyroid, it also reduces the formation of thyroxine, hence reducing the production of the thyroid hormones (T3 and T4).
REFERENCES
1. Gregory A. Brent and Ronald J. Koenig. Thyroid and Antithyroid Drugs. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical. 2018. Page – 787-801.
2. Chiu Chi Tsang,Wai Shan Hui, Kwun Man Lo, Jonas Hon Ming Yeung, and Yuk Lun Cheng. Anti-Thyroid Drugs-Related Myopathy: Is Carbimazole the Real Culprit? National Library of Medicine, National center for biotechnology information. PubMed central. January 2015 [Accessed on 2nd May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338648/
3. Henry B Burch and David S Cooper. Antithyroid drug therapy: 70 years later. European journal of Endocrinology. November 2018 [Accessed on 2nd May 2022] https://eje.bioscientifica.com/view/journals/eje/179/5/EJE-18-0678.xml
4. Tioarma B.V. Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 2nd May 2022] https://www.medicines.org.uk/emc/files/pil.10283.pdf
5. Central Pharma (Contract Packing) Limited. Electronic Medicines Compendium (EMC). [Revised in November 2020] [Accessed on 2nd May 2022] https://www.medicines.org.uk/emc/files/pil.10328.pdf
USEFUL DIAGNOSTIC TESTS
- Thyroid test
- Completed blood count
- Liver function test
AUTHOR DETAILS
Written By Dr. Shruthi M R, BDS
Last updated on 13 Jan 2023 | 10:06 AM(IST)
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