INTRODUCTION

NANOPACLI 100MG contains Paclitaxel which belongs to a group of anti-cancer medicines called Taxanes. It is used to treat various forms of ovarian cancer, breast cancer, lung cancer and Kaposi’s sarcoma. Cancer is a disease in which some of the body’s cells grow uncontrollably and spread to other parts of the body. This medicine will be given as an injection by a healthcare professional.

Paclitaxel belongs to antineoplastic agents, which works by interfering with the microtubule structures (they help the cancer cells to divide and multiply). This slows the growth of cancer cells and eventually destroys them.

Before receiving NANOPACLI 100MG, tell your doctor about your complete medical history including infections, heart-problem, liver impairment, kidney malfunction and low white blood cell counts. It is not recommended for use during pregnancy and breastfeeding. The common side effects are dizziness, nausea, vomiting, weakness, tiredness and hair loss. Women of childbearing potential should be advised to avoid becoming pregnant.

USES OF NANOPACLI 100MG

Treats,

• ovarian cancer
• breast cancer
• lung cancer
• Kaposi’s sarcoma

HOW NANOPACLI 100MG WORKS

NANOPACLI 100MG works by stopping cancer cells from separating into two new cells and blocks the growth of the cancer.

DIRECTIONS FOR USE

NANOPACLI 100MG will be administered into a vein by your doctor or nurse.

SIDE EFFECTS OF NANOPACLI 100MG

HOW TO MANAGE SIDE EFFECTS

Nausea:

Take routine meals and avoid spicy foods.

Vomiting:

Drink clear or ice-cold drinks and avoid sweets.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug - Drug interactions:

Inform your physician if you are taking,

• erythromycin, rifampicin (treats infections)
• ketoconazole (treats fungal infections)
• fluoxetine (used to stabilize your mood)
• carbamazepine, phenytoin (treats epilepsy)
• gemfibrozil (lower lipid levels)
• cimetidine (used for heartburn)
• ritonavir, saquinavir, indinavir, nelfinavir, efavirenz, nevirapine (used to treat HIV and AIDS)
• clopidogrel (used to prevent blood clots)

Overdosage:

• There is no known antidote for NANOPACLI 100MG over dosage. In case of overdose, it should be closely monitored.

SYNOPSIS

MORE INFORMATION

• Keep out of reach of children
• Do not store above 25°C

FAQs ABOUT NANOPACLI 100MG

Does NANOPACLI 100MG cause hair loss?

Yes, it may cause hair loss as a side effect in some individuals. Consult your doctor for advice.

How is NANOPACLI 100MG given?

It is given as an IV infusion into the vein (intravenous, IV).

How long does NANOPACLI 100MG stay in the body?

This medicine itself stays in the body within 2 -3 days of treatment but there are short-term and long-term side effects that patients may experience.

REFERENCES

1. KD. Tripathi. Anticancer drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page –865.

2. Hospira; [Revised on April, 2021] [Accessed on Oct 07, 2021] http://labeling.pfizer.com/ShowLabeling.aspx?id=4559

3. Zeventus Healthcare; [Accessed on Oct 07, 2021] http://www.zuventus.co.in/patient_wise_products_selected.aspx?Medi_Id=133

4. Drugs.com. Paclitaxel; [Revised on July 21, 2020] [Accessed on Oct 07, 2021] https://www.drugs.com/ppa/paclitaxel-conventional.html

5. Cancer research UK; [Revised on April 02, 2019] [Accessed on Oct 07, 2021] https://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatment/cancer-drugs/drugs/paclitaxel

6. Cipla Ltd; [Revised on Dec, 2016] [Accessed on Oct 07, 2021] https://www.ciplamed.com/print-product-pdf/24159

7. Chemo care; [Accessed on Oct 07, 2021] https://chemocare.com/chemotherapy/drug-info/paclitaxel.aspx

8. Accord Healthcare Limited. Medicines Compendium (EMC); [Revised on Dec, 2019] [Accessed on Oct 07, 2021] https://www.medicines.org.uk/emc/files/pil.6076.pdf

USEFUL DIAGNOSTIC TESTS

• Breast Cancer (CA 15.3/ ER/ PR)
• Carcino Embryonic Antigen