INTRODUCTION

MOXIZEST EYE OINTMENT contains Moxifloxacin which belongs to the group of medicines called Antibiotics. It is used for the treatment of bacterial conjunctivitis.

Bacterial conjunctivitis is the infection of the transparent membrane (conjunctiva) that lines the eyelid and covers the white part of your eyeball. Symptoms of bacterial conjunctivitis include pain, discomfort, redness, itching, irritation, and watery eyes.

Patients should be advised not to wear contact lenses if they have signs and symptoms of bacterial conjunctivitis.

MOXIZEST EYE OINTMENT should be used with caution in pregnant women or if you think you may be pregnant and in breastfeeding woman. Consult your doctor before using.

The safety and effectiveness of MOXIZEST EYE OINTMENT in infants below 1 year of age have not been established. Consult your doctor for advice before using this medicine.

MOXIZEST EYE OINTMENT should be used with caution in elderly patients of above 65 years of age. The common side effects are eye pain or irritation. Consult your doctor if the symptom does not improve.

USES OF MOXIZEST EYE OINTMENT

• Used to treat bacterial conjunctivitis

HOW MOXIZEST EYE OINTMENT WORKS

MOXIZEST EYE OINTMENT works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV which are required for DNA replication and transcription resulting in cell death. This prevents the bacterial cells from dividing and repairing and destroys them.

DIRECTIONS FOR USE

Apply MOXIZEST EYE OINTMENT as advised by your physician. It is for topical ophthalmic use only. Your doctor will prescribe the right dose depends on your age, body weight and severity of the infection.

Hold the tube close to the eye without touching it. Gently squeeze the tube and place the medicine inside the lower eyelid. Do not touch the applicator tip to any surface to avoid contaminating the contents.

SIDE EFFECTS OF MOXIZEST EYE OINTMENT

HOW TO MANAGE SIDE EFFECTS

Vomiting:

Stick to simple meals. Try to Avoid oil rich or spicy foods, sugary snacks, and drinks. Try to drink liquid slowly along with your meals, or in between meals. Consult your doctor if your symptom is not improving.

Headache:

Apply hot or cold-water bag on your head. Try to take rest in a quiet and dark room. Drink tea or coffee. Massage on scalp or head with mild pressure. Consult your doctor for advice.

Blurred vision:

This happens immediately after putting the medicine and is usually temporary. Wait until your vision becomes clear before you start doing normal works.

Eye itching or burning:

Close your eyes and relax for some time. Place an ice pack over the eyes for few minutes. Avoid watching mobile phone, system, laptop, or any other light sources which might irritate your eyes. If the symptom persists or worsens, contact your doctor.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Inform your doctor if you are taking, applying or have recently taken any other medicines, including prescription, non-prescription and herbal supplements.

Overdosage:

If you or anyone else accidentally applies too much of MOXIZEST EYE OINTMENT, consult your doctor immediately or visit the nearby hospital. Wash your eyes and rinse it all out with warm water.

SYNOPSIS

MORE INFORMATION

• Keep out of reach of children
• Store at room temperature

FAQs ABOUT MOXIZEST EYE OINTMENT

What is MOXIZEST EYE OINTMENT and why it is given?

MOXIZEST EYE OINTMENT contains moxifloxacin which is used to treat bacterial conjunctivitis.

How does MOXIZEST EYE OINTMENT works?

MOXIZEST EYE OINTMENT works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV which are required for DNA replication and transcription resulting in cell death. This prevents the bacterial cells from dividing and repairing and destroys them.

Does MOXIZEST EYE OINTMENT cause eye irritation?

Yes, it may cause itching and burning sensation of eyes in some patients. Close your eyes and relax for some time. Place an ice pack over the eyes for few minutes. Avoid watching mobile phone, system, laptop, or any other light sources which might irritate your eyes. If the symptom persists or worsens, contact your doctor.

Can I stop applying MOXIZEST EYE OINTMENT without consulting a doctor?

No. Do not abruptly stop applying MOXIZEST EYE OINTMENT without consulting your doctor. Continue to use this medicine, as long as your doctor tells you to do so, to obtain better results.

Can MOXIZEST EYE OINTMENT be used in children?

MOXIZEST EYE OINTMENT is not recommended for use in infants below 1 year of age. Consult your doctor for advice before applying the medicine.

REFERENCES

1. KD. Tripathi. Sulfonamides, Cotrimoxazole and Quinolones. Essentials of medical pharmacology. Eighth edition. 2013. Page – 764.

2. Darlene Miller. Review of moxifloxacin hydrochloride ophthalmic solution in the treatment of bacterial eye infections. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. March 2008. [Accessed 30th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698721/

3. Panel Barry A.SchlechPhD, EduardoAlfonsoMD. Overview of the Potency of Moxifloxacin Ophthalmic Solution 0.5% (VIGAMOX®). ScienceDirect. November 2005. [Accessed 30th June 2022] https://www.sciencedirect.com/science/article/abs/pii/S0039625705000524

4. Cipla Ltd.  Sep 19, 2014. [Revised in October 2019]. [Accessed 30th June 2022] https://ciplamed.com/content/moxicip-eye-ointment

5. Centaur pharma. [Accessed 30th June 2022] https://www.centaurpharma.com/downloads/Centaflox%20eye%20ointment.pdf

6. Sunways. [Accessed 30th June 2022] http://www.sunways.com/Products/SunwaysProducts/Occumox.html