INTRODUCTION

MOXIZEST L OPHTHALMIC SUSPENSION is a combination of Loteprednol and Moxifloxacin which belongs to the group of medicines called Corticosteroids and Antibiotics respectively. MOXIZEST L OPHTHALMIC SUSPENSION is used in the treatment of postoperative steroid responsive inflammatory ocular infections or risk of bacterial ocular infections exists.

Before using MOXIZEST L OPHTHALMIC SUSPENSION, your doctor may want you to take relevant tests to understand your existing condition. Do not wear contact lenses if you have an active eye infection or while using this medicine.

MOXIZEST L OPHTHALMIC SUSPENSION is not recommended for use in patients with viral diseases of the cornea and conjunctiva including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella, and also in mycobacterial infection of the eye and fungal diseases of ocular structures.

Before using MOXIZEST L OPHTHALMIC SUSPENSION, inform your doctor if you have diabetes, increased pressure in the eye, glaucoma, damage of nerves supplying the eye, any visual disturbances, cataract, delay in healing, pus discharge from the eye.

There are no adequate data available for the use of MOXIZEST L OPHTHALMIC SUSPENSION during pregnancy, lactation and in infants. Consult your doctor before using this medicine.

Prolonged use of MOXIZEST L OPHTHALMIC SUSPENSION may result in overgrowth of non-susceptible organisms, including fungi. Cataract formation and delayed wound healing can happen with prolonged usage.  

The most common side effects of using MOXIZEST L OPHTHALMIC SUSPENSION are decreased visual acuity, dry eye, keratitis, ocular discomfort, ocular hyperemia, ocular pain, ocular pruritus, sub-conjunctival hemorrhage, tearing, optic nerve damage. Consult your doctor if any of the above side effects worsen.

USES OF MOXIZEST L OPHTHALMIC SUSPENSION

• Used in the treatment of postoperative steroid responsive inflammatory ocular infections or risk of bacterial ocular infections exists

HOW MOXIZEST L OPHTHALMIC SUSPENSION WORKS

MOXIZEST L OPHTHALMIC SUSPENSION is a combination of Loteprednol and Moxifloxacin. Loteprednol belongs to steroid which blocks the production of certain chemical messengers (prostaglandins) that make the eye red, swollen and itchy. Moxifloxacin belongs to antibiotic which prevents bacterial cells from dividing and repairing, thereby works against the bacteria.

DIRECTIONS FOR USE

Use MOXIZEST L OPHTHALMIC SUSPENSION as directed by your doctor. It is for ophthalmic use only. Instill one to two drops into the eye as advised by your doctor. Avoid touching the nostril tip of the medicine with your hands or eye surface to avoid contamination.

SIDE EFFECTS OF MOXIZEST L OPHTHALMIC SUSPENSION

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before using MOXIZEST L OPHTHALMIC SUSPENSION inform your doctor if you are taking any of the following medicines:

• cycloplegics (medicines that paralyze the ciliary muscles and cause relaxation of accommodation)

Overdosage:

If you or anyone else accidentally uses too much of MOXIZEST L OPHTHALMIC SUSPENSION, rinse your eyes externally with clean/lukewarm water and consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep out of reach from children
• Store at room temperature

FAQs ABOUT MOXIZEST L OPHTHALMIC SUSPENSION

Q: Is [GBBNKEYWORD] safe for use in patients with viral infections?

A: Patients with a viral disease (such as varicella, vaccinia, herpes simplex, and other viral infections of the eye) or fungal infection of the eye should not use MOXIZEST L OPHTHALMIC SUSPENSION. Consult your doctor before using it.

Q: Is [GBBNKEYWORD] safe for use during pregnancy and breastfeeding?

A: There are no adequate data available for the use of MOXIZEST L OPHTHALMIC SUSPENSION during pregnancy and lactation. Consult your doctor before using this medicine.

Q: What to do if [GBBNKEYWORD] accidentally used in excess?

A: If you or anyone else have accidentally used MOXIZEST L OPHTHALMIC SUSPENSION in excess, rinse the external surface of the eye with lukewarm water immediately. Consult your doctor immediately or visit the nearby hospital immediately if you are experiencing worsening symptoms.

Q: Can I drive after using [GBBNKEYWORD]?

A: Do not drive or operate any machinery if you experience blurred or impaired vision after using MOXIZEST L OPHTHALMIC SUSPENSION.

REFERENCES

1. KD. Tripathi. Antimicrobial drugs, NSAIDs and antipyretic-analgesics. Essentials of medical pharmacology. 8th Edition. 2019. Page –219, 764.

2. Darlene Miller. National Library of Medicine (NIH). Review of Moxifloxacin hydrochloride ophthalmic solution in the treatment of bacterial eye infections. [Revised on March 2008] [Accessed on 17th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698721/

3. Michael and Massimo Busin. National Library of Medicine (NIH). Loteprednol etabonate ophthalmic suspension 0.5 %: efficacy and safety for postoperative anti-inflammatory use. [Revised on 16th June 2012] [Accessed on 17th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459083/

4. Novartis Ireland Limited. Electronic Medicines Compendium (EMC). Moxivig 0.5% w/v eye drops, solution. [Revised on October 2021] [Accessed on 17th May 2022] https://www.medicines.org.uk/emc/files/pil.5721.pdf

5. Bausch Health Poland sp. Electronic Medicines Compendium (EMC). Yellox 0.9 mg/ml eye drops, solution, Bromfenac. [Revised on February 2021] [Accessed on 17th May 2022] https://www.medicines.org.uk/emc/product/6212/pil

6. Bausch & Lomb Incorporated. U.S. Food and Drug Administration (FDA). [Revised on September 2012] [Accessed on 17th May 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202872lbl.pdf

7. Micro labs Ltd. [Accessed on 17th May 2022] http://www.microlabsltd.com/elibrary/node/1811