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INTRODUCTION
MOXIFAX EYE DROPS is a combination of Hydroxy Propyl Methylcellulose and Moxifloxacin which belongs to the group of medicines called Eye lubricants and Antibiotics respectively. MOXIFAX EYE DROPS is used in post-cataract surgery and in bacterial conjunctivitis. Conjunctivitis (pink eye) is an inflammation or infection of the conjunctiva (transparent membrane) that lines the eyelid and covers the white part of the eyeball.
MOXIFAX EYE DROPS is not recommended for use if you are wearing soft contact lenses and it should not be injected subconjunctivally nor should it be introduced directly into the anterior chamber of the eye.
Before using MOXIFAX EYE DROPS inform your doctor if you have a headache or eye pain, vision changes and permanent red eyes. MOXIFAX EYE DROPS should be used with caution among women who are pregnant or breastfeeding.
MOXIFAX EYE DROPS is not recommended in new-born and it should be used with caution in children (aged above 1 year and more). The most common side effects of using MOXIFAX EYE DROPS are eye pain, eye irritation or itching, decreased visual acuity and ocular discomfort. Consult your doctor if any of the side effects worsen.
USES OF MOXIFAX EYE DROPS
- Treats bacterial conjunctivitis
HOW MOXIFAX EYE DROPS WORKS
MOXIFAX EYE DROPS is a combination of Hydroxy Propyl Methylcellulose and Moxifloxacin. Hydroxy Propyl Methylcellulose works by moistening, soothing and lubricating the surface of the eye, making it feel more comfortable. Moxifloxacin works by stopping the action of a bacterial enzyme called DNA-gyrase thereby, preventing the bacteria from dividing and repairing, thus helpful in treating the bacterial infection of the eye.
DIRECTIONS FOR USE
Use MOXIFAX EYE DROPS as advised by your doctor. It is for external use only. Do not touch the tip of the dropper on any surface. Squeeze the dropper gently, then dispense the medication inside the lower eyelid. Your doctor will decide the correct dose and duration for you depending upon your age, disease condition and body weight.
SIDE EFFECTS OF MOXIFAX EYE DROPS
COMMON
- eye pain
- eye irritation or itching
- decreased visual acuity
- keratitis, ocular discomfort
- ocular hyperaemia, ocular pain
- subconjunctival haemorrhage and tearing
UNCOMMON
- dry eye
- eye surface inflammation or scarring
- a broken blood vessel in the eye
- eyelid abnormality
- headache
RARE
- inflammation or infection of the conjunctiva
- eye strain
- vomiting
- nose discomfort, throat irritation
- a sense of a lump in the throat
- abnormal skin sensation
Stop using MOXIFAX EYE DROPS and contact your physician immediately if you experience any of the following side effects:
- severe allergic reaction (symptoms include swelling of the hands, feet, ankles, face, lips, mouth or throat which may cause difficulty in breathing or swallowing, rash or hives, large fluid-filled blisters, sores and ulceration)
- eye infection
HOW TO MANAGE SIDE EFFECTS
Eye irritation or itching:
Wash your eyes with plain cold water. Place an ice pack on your eye to soothe the irritation. Avoid straining your eyes by keeping away from mobile phones, laptops or television. Wear protective sunglasses while going outdoors. Consult your doctor if the symptom does not improve.
Eye Pain:
Rest your eyes by closing or sleeping. Avoid bright lights, reading, watching the television, and working on the computer. Keep eyes closed and gently massage your eyes for few seconds to relieve the muscles. Consult your doctor if the symptom does not improve.
WARNING & PRECAUTIONS
PREGNANCY
MOXIFAX EYE DROPS should be used with caution in pregnant women unless considered clearly necessary. Consult your doctor before using it.
BREASTFEEDING
MOXIFAX EYE DROPS should be used with caution in breastfeeding women. Consult your doctor before using it.
DRIVING AND USING MACHINES
Do not drive or operate machinery if you are not sure if you have complete mental and motor coordination after using MOXIFAX EYE DROPS.
ALCOHOL
Avoid consumption of alcohol while using MOXIFAX EYE DROPS.
ALLERGY
Do not use MOXIFAX EYE DROPS if you are allergic to Hydroxy Propyl Methylcellulose, Moxifloxacin, other quinolones such as ofloxacin or any other ingredients of this medicine.
OTHERS
MOXIFAX EYE DROPS is not recommended for you, if you:
- wear soft contact lenses
Before using MOXIFAX EYE DROPS, inform your doctor if you have:
- headache or eye pain
- vision changes
- permanent red eyes
Use in pediatrics:
MOXIFAX EYE DROPS should be used with caution in children (aged above 1 year and more). The use of MOXIFAX EYE DROPS is not recommended in new-born. Consult your child’s doctor for advice.
Use in geriatrics:
MOXIFAX EYE DROPS should be used with caution in elderly patients (aged above 65 years). Consult your doctor for advice before using MOXIFAX EYE DROPS.
INTERACTIONS
A. Drug-Drug interactions:
Before using MOXIFAX EYE DROPS, inform your doctor if you are taking any of the following medicines:
- medicines used to treat bacterial infection either orally or intravenously (Ex. fluoroquinolones like norfloxacin, ofloxacin)
- medicines used as an anti-inflammatory (Ex. corticosteroids like prednisolone)
- other eye drops or eye ointment
Overdosage:
If you or anyone else accidentally use too much of MOXIFAX EYE DROPS, rinse it all out with warm water. Do not put any more drops until it is time for the next dose. In case of any undesirable effects consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Hydroxy Propyl Methylcellulose, Moxifloxacin |
| Pharmacological Category | : | Eye lubricants, Antibiotics |
| Therapeutic Indication | : | Post-cataract surgery and bacterial conjunctivitis |
| Dosage Forms | : | Eye drops |
MORE INFORMATION
- Keep MOXIFAX EYE DROPS out of reach of children
- Store at a temperature, not more than 25°C
FAQs ABOUT MOXIFAX EYE DROPS
Q: Can I stop using MOXIFAX EYE DROPS if I feel better?
A: Do not stop using MOXIFAX EYE DROPS without contacting your physician even if your condition improves. Sudden discontinuation can make the infection worse. Inform your physician if there is no considerable improvement in your condition.
Q: Is MOXIFAX EYE DROPS safe to use in infants?
A: MOXIFAX EYE DROPS should be used with caution in children (aged above 1 year and more). The use of MOXIFAX EYE DROPS is not recommended in new-born. Consult with your child’s doctor for advice.
Q: What if I forget to use a dose of MOXIFAX EYE DROPS?
A: If you forget to use a dose of MOXIFAX EYE DROPS, use it as soon as you remember. However, omit the missed dose if it is almost time for the next one. Do not use the medicine two times to make up for a forgotten dose.
Q: Can I drive after using MOXIFAX EYE DROPS?
A: Do not drive or operate machinery if you are not sure if you have complete mental and motor coordination after using MOXIFAX EYE DROPS. Consult your doctor for advice before using it.
Q: How to use MOXIFAX EYE DROPS?
A: Use MOXIFAX EYE DROPS as advised by your doctor. It is for external use only. Do not touch the tip of the dropper on any surface. Squeeze the dropper gently, then dispense the medication inside the lower eyelid. Your doctor will decide the correct dose and duration for you depending upon your age, disease condition and body weight.
REFERENCES
1. Conan MacDougall. Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones and Agents for Urinary Tract Infections. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical 2018. Page – 1016
2. KD. Tripathi. Sulfonamides, Cotrimoxazole and Quinolones. Essentials of medical pharmacology. Seventh edition. 2013. Page – 704-715
3. Paul M. Tulkens, Pierre Arvis and Frank Kruesmann. Moxifloxacin Safety. Journal of Drugs in R & D. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. June 2012 [Accessed on 27th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585838/
4. Gillian M Keating, Lesley J Scott. Moxifloxacin: a review of its use in the management of bacterial infection. Journal of Drugs. September 2004 [Accessed on 27th June 2022] https://www.researchgate.net/publication/282112559_Moxifloxacin_a_review_of_its_use_in_the_management_of_bacterial_infections
5. Centaflox Eye drops (Moxifloxacin and Hydroxy Propyl Methylcellulose) . www.centaurpharma.com. [Accessed on 27th June 2022] https://www.centaurpharma.com/downloads/ophthalmology/anti-infectives/Centaflox.pdf
6. Novartis Ireland Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed 27th June 2022] https://www.medicines.org.uk/emc/files/pil.5721.pdf
7. Martindale Pharmaceuticals Ltd. Electronic Medicines Compendium (EMC). [Revised in January 2021] [Accessed 27th June 2022] https://www.medicines.org.uk/emc/files/pil.3537.pdf
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