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INTRODUCTION
MOTINORM DROPS contain domperidone which belongs to a group of medicine called dopamine antagonists. It is used to treat nausea and vomiting in adults and adolescents. It increases the movement of food through the stomach and the digestive tract more quickly, thus reducing the feeling of bloating, fullness and indigestion. It works by blocking the action of a chemical in your brain which causes the feeling of nausea and vomiting.
This medicine is strictly not recommended for use in children and adolescents under 12 years of age and older with a body weight of less than 35kg. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine. The most common side effect of this medicine is dry mouth.
USES OF MOTINORM DROPS
- Treat nausea and vomiting
HOW MOTINORM DROPS WORKS
MOTINORM DROPS increases the movement of food through the stomach and the digestive tract more quickly, thus reducing the feeling of bloating, fullness and indigestion. It also works by blocking the action of a chemical in your brain which causes the feeling of nausea and vomiting.
DIRECTIONS FOR USE
Always use MOTINORM DROPS exactly as your doctor has told you. Check the label for directions before use. Shake well before use.
SIDE EFFECTS OF MOTINORM DROPS
SERIOUS
- allergic reaction such as swelling of the hands, feet, ankles, face, lips, or throat which may cause difficulty in swallowing or breathing, itching, lumpy rash (hives) or nettle rash (urticaria)
- uncontrolled movements symptoms such as irregular eye movements, unusual movements of the tongue, and abnormal posture such as a twisted neck, trembling and muscle stiffness
- very fast or unusual heartbeat
- fit (seizure)
COMMON
- dry mouth
HOW TO MANAGE SIDE EFFECTS
Itching:
Apply a cold, wet cloth, or ice pack on the itching area. Take an oatmeal bath. Moisturize your skin. Apply cooling agents such as menthol and calamine.
WARNING & PRECAUTIONS
PREGNANCY
MOTINORM DROPS should be used with caution in pregnant women. Consult your doctor before taking this medicine.
BREASTFEEDING
MOTINORM DROPS is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
MOTINORM DROPS does not affect your ability to drive or use machines.
ALCOHOL
Consumption of alcohol is not recommended during treatment with MOTINORM DROPS.
KIDNEY
MOTINORM DROPS should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.
LIVER
MOTINORM DROPS is not recommended in patients with active liver diseases. Before taking this medicine consult your doctor.
ALLERGY
Do not take MOTINORM DROPS if you are allergic (hypersensitive) to domperidone or any other ingredients in this medicine.
HEART DISEASE
MOTINORM DROPS is not recommended in patients with active heart diseases. Before taking this medicine consult your doctor.
OTHERS
Tell your doctor if you have or had a condition such as,
- a tumour of the pituitary gland (prolactinoma)
- a blockage or tear in your intestines
- black, tarry bowel motions (stools) or blood in your bowel motions (symptoms of bleeding in the stomach or intestines)
- a problem that gives you a low level of potassium or magnesium, or a high level of potassium in your blood
- AIDS/HIV
INTERACTIONS
Talk to your doctor if you are taking,
- azole anti-fungals, specifically oral ketoconazole, fluconazole or voriconazole (used to treat fungal infections)
- antibiotics such as erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine (used to treat bacterial infections)
- amiodarone, dronedarone, quinidine, disopyramide, dofetilide, sotalol, diltiazem, verapamil (used to treat heart problems or high blood pressure)
- haloperidol, pimozide, sertindole (used to treat psychoses)
- citalopram, escitalopram (used to treat depression)
- cisapride, dolasetron, prucalopride (used to treat Gastro-intestinal disorders)
- mequitazine, mizolastine (used to treat allergy)
- halofantrine (used to treat malaria)
- protease inhibitors (used to treat AIDS/HIV)
- toremifene, vandetanib, vincamine (used to treat cancer)
SYNOPSIS
| Drug | : | Domperidone |
| Pharmacological Category | : | Dopamine antagonists |
| Therapeutic Indication | : | Nausea and vomiting |
| Dosage Forms | : | Tablet, Capsule, Oral drops, Oral suspension |
MORE INFORMATION
Store below 20-25°C and keep out of reach of children.
FAQs ABOUT MOTINORM DROPS
Is MOTINORM DROPS safe?
Yes, it is safe if used at prescribed doses for the prescribed duration as advised by your physician.
Can MOTINORM DROPS cause itching?
Yes, this medicine may cause itching in some individuals. Apply a cold, wet cloth, or ice pack on the itching area. Take an oatmeal bath. Moisturize your skin. Apply cooling agents such as menthol and calamine.
Can I take MOTINORM DROPS for morning sickness?
No, it is not indicated or recommended for treating morning sickness.
REFERENCES
1. KD Tripathi. Antiemetic, Prokinetic and Digestant Drugs. Essentials of Medical Pharmacology. Seventh Edition,2013. Page - 666-667.
2. A J Reyntjens, C J Niemegeers, J M Van Nueten, P Laduron, J Heykants, K H Schellekens, R Marsboom, A Jageneau, A Broekaert, P A Janssen. Domperidone, a novel and safe gastrokinetic anti-nauseant for the treatment of dyspepsia and vomiting. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov.1978. [Accessed 06 Feb 2021] https://pubmed.ncbi.nlm.nih.gov/582708/
3. Sofarimex-industria Quimica e Farmaceutica Lda; Electronic Medicines Compendium (EMC); [Revised on Mar 2020] [Accessed 06 Feb 2021] https://www.medicines.org.uk/emc/files/pil.3188.pdf
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