MIRZEST 7.5mg Tablet 10's

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Drug Information for MIRZEST 7.5mg Tablet 10's

What is MIRZEST?

  • MIRZEST contains mirtazapine which belongs to a group of medicines called antidepressants







What MIRZEST is used for?

  • MIRZEST is used to treat depressive illness in adults
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Tell your doctor before taking this medicine, if you:

  • are allergic to mirtazapine or any of the other ingredients of this medicine
  • are depressed you can sometimes have suicidal thoughts or harming yourself
  • have seizures (epilepsy)
  • suffer from kidney or liver disease
  • suffer from heart disease
  • have low blood pressure
  • have diabetes
  • have eye disease, such as increased pressure in the eye (glaucoma)
  • have difficulty in passing water (urinating), which might be caused by an enlarged prostate
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  • If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine
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  • MIRZEST should not be used for children and adolescents under 18 years because efficacy is not demonstrated. Consult your doctor before taking this medicine
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  • MIRZEST can affect your concentration or alertness. Make sure these abilities are not affected before you drive or operate machinery
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Tell your doctor if you are taking,

  • monoamine oxidase inhibitors (MAO inhibitors) such as moclobemide, tranylcypromine (both are antidepressants) and selegiline (used for Parkinson’s disease)
  • antidepressants such as SSRIs, venlafaxine and L-tryptophan, or triptans (used to treat migraine) and nefazodone
  • methylene blue (used to treat high levels of methemoglobin in the blood)
  • St.John’s Wort – Hypericum perforatum preparations (an herbal remedy for depression)
  • benzodiazepines for anxiety or insomnia 
  • olanzapine for schizophrenia
  • cetirizine for allergies 
  • morphine, tramadol for severe pain 
  • erythromycin for bacterial infections 
  • ketoconazole for fungal infections 
  • medicines for HIV/AIDS
  • carbamazepine and phenytoin for epilepsy
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  • Always take this medicine exactly as your doctor has told you
  • The recommended starting dose is 15 or 30 mg every day
  • Your doctor may advise you to increase your dose after a few days to the amount that is best for you
  • The dose is usually the same for all ages. However, if you are an elderly person or if you have renal or liver disease, your doctor may adapt the dose
  • Take MIRZEST at the same time each day. It is best to take MIRZEST as a single dose before you go to bed
  • However, your doctor may suggest splitting your dose of MIRZEST once in the morning and once at night-time before you go to bed
  • The higher dose should be taken before you go to bed
  • Take your tablet orally
  • Swallow your tablets without chewing, with some water or juice

If you take more MIRZEST 

  • If you or someone else have taken too much MIRZEST, call a doctor straight away

If you forget to take MIRZEST 

  • If you forget to take your dose
  • Do not take a double dose to make up for a forgotten dose. Take your next dose at the normal time

If you stop taking MIRZEST 

  • Do not suddenly stop taking MIRZEST, even when your depression has lifted
  • If you suddenly stop taking MIRZEST you may feel sick, dizzy, agitated or anxious, and have headaches. Only stop taking MIRZEST after consulting with your doctor
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Like all medicines, this medicine can cause side effects, although not everybody gets them.




  • constipation
  • lethargy
  • dizziness, tiredness
  • shakiness or tremor
  • stomach upset
  • rash or skin eruptions (exanthema)
  • pain in your joints (arthralgia) or muscles (myalgia)
  • back pain
  • swelling (typically in ankles or feet) caused by fluid retention (oedema)
  • vivid dreams
  • confusion
  • feeling anxious
  • sleeping problems
  • increase in appetite and weight gain
  • drowsiness or sleepiness
  • headache, dry mouth
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  • feeling elated or emotionally ‘high’ (mania)
  • abnormal sensation in the skin e.g. burning, stinging, tickling or tingling (paraesthesia)
  • restless legs
  • fainting (syncope)
  • sensations of numbness in the mouth (oral hypoaesthesia)
  • low blood pressure
  • nightmares
  • feeling agitated
  • hallucinations
  • urge to move
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  • muscle twitching or contractions (myoclonus)
  • aggression
  • inflammation of the pancreas (pancreatitis) marked by abdominal pain and nausea
  • yellow coloring of eyes or skin
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  • Keep this medicine out of reach of children
  • Do not use this medicine after the expiry date
  • Store at room temperature (15-25°C)
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The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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