INTRODUCTION

MIRAKEM 50MG contain mirabegron which belongs to a group of medicine called beta 3-adrenoceptor agonist (bladder muscle relaxant) which reduces the activity of an overactive bladder and treats the related symptoms. This medicine is used to treat the symptoms of an overactive bladder in adults such as urgency to empty your bladder, increased urinary frequency, not able to control when to empty your bladder (called urgency incontinence). It works by activating the receptor in the bladder, causing the bladder muscles to relax. It prevents frequent, urgent, or uncontrolled urination.

Always take MIRAKEM 50MG exactly as your doctor has told you. This medicine must be taken with or without food. This medicine is strictly not recommended for use in children and adolescents under 18 years. Consumption of alcohol is not recommended during treatment with this medicine. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine. The common side effects are tachycardia, urinary tract infections, nausea, constipation, headache, diarrhoea, dizziness.

USES OF MIRAKEM 50MG

• Treat the symptoms of an overactive bladder in adults

HOW MIRAKEM 50MG WORKS

MIRAKEM 50MG works by activating the receptor in the bladder, causing the bladder muscles to relax. It prevents frequent, urgent, or uncontrolled urination.

DIRECTIONS FOR USE

Always take MIRAKEM 50MG exactly as your doctor has told you. This medicine must be taken with or without food. Try to take this medicine at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine.

SIDE EFFECTS OF MIRAKEM 50MG

HOW TO MANAGE SIDE EFFECTS

Nausea:

Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

Constipation: 

Take fibre rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Diarrhoea:

Drink lot of fluids, such as water or squash, to avoid dehydration. Do not take any other medicines without consulting to a doctor.

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor if you are taking,

• thioridazine (used to treat mental illness)
• propafenone or flecainide, digoxin, quinidine, sotalol, procainamide, ibutilide, flecainide, dofetilide, and amiodarone (used to treat abnormal heart rhythm)
• imipramine or desipramine (used to treat depression)
• dabigatran etexilate (used to reduce the risk of brain or body vessel obstruction by blood clot formation in adult patients with an abnormal heartbeat)
• itraconazole, ketoconazole (used to treat fungal infections)
• ritonavir (used to treat HIV/AIDS)
• medicines used for allergic rhinitis
• antipsychotic medicines such as thioridazine, mesoridazine, haloperidol, chlorpromazine
• anti-infectives such as pentamidine, moxifloxacin, erythromycin, and clarithromycin (used to treat infections)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT MIRAKEM 50MG

Does MIRAKEM 50MG cause loss of sleep?

No, it does not affect your sleep. However, if you are having any problems related to your sleep, consult your doctor.

Do I need to be careful while taking MIRAKEM 50MG if I am taking medicines to control my blood pressure?

Yes, you need to be careful while taking this medicine if you have high blood pressure. Keep a regular check on your blood pressure since this medicine can cause an increase in blood pressure in some people. It should not be used in patients with severe uncontrolled hypertension.

Can I take MIRAKEM 50MG during diarrhoea?

Yes, it may cause diarrhoea in some individuals. Drink lot of fluids, such as water or squash, to avoid dehydration. Do not take any other medicines without consulting to a doctor.

REFERENCES

1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page - 2597- 2598.

2. Katherine Warren, Helena Burden, and Paul Abrams. Mirabegron in overactive bladder patients: efficacy review and update on drug safety. US National Library of Medicines, National Institutes of Health. 19 Jul 2016. [Accessed 28 Nov 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014049/

3. Astellas Pharma Europe B.V; Electronic Medicines Compendium (EMC); [Revised on Apr 2019] [Accessed 28 Nov 2020] https://www.medicines.org.uk/emc/files/pil.2977.pdf

USEFUL DIAGNOSTIC TESTS

• Urine Routine and Microscopy