METOZEST XL 12.5 Tablet 10's

Hypertension Rx required

Best Price* ₹ 29.20 MRP ₹ 36.50
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Innovative Pharmaceuticals Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

METOZEST XL 12.5 TABLET contains Metoprolol, which belongs to the group of medicines called Beta-blockers. It is used to treat high blood pressure, angina pectoris (chest pain), and heart failure. It is also used to treat arrhythmias or palpitations, and to prevent heart attacks and migraines.

Avoid alcohol consumption while taking METOZEST XL 12.5 TABLET as it lowers blood pressure. METOZEST XL 12.5 TABLET is not recommended for use in patients with asthma, COPD, severe bradycardia, second or third-degree heart block, cardiogenic shock, decompensated cardiac failure, sick sinus syndrome (unless a permanent pacemaker is present) and untreated pheochromocytoma. METOZEST XL 12.5 TABLET should be used with caution in patients with diabetes, stroke, liver or kidney disease, myocardial infarction, angina pectoris, and heart failure.

METOZEST XL 12.5 TABLET is not recommended for use in pregnant women unless considered necessary. METOZEST XL 12.5 TABLET should be used with caution in breastfeeding women, as it may pass through breast milk. METOZEST XL 12.5 TABLET is not recommended for use in children less than 6 years of age. METOZEST XL 12.5 TABLET should be used with caution in elderly patients aged 65 years or above.

The most common side effects of taking METOZEST XL 12.5 TABLET are experiencing faints upon standing due to low blood pressure, tiredness, slow heartbeat, palpitations, dizziness, headache, cold hands, and feet, etc. Contact your physician if any of your symptoms get worse or persist.

USES OF METOZEST XL 12.5 TABLET

Treats:

  • Treats high blood pressure
  • Treats angina pectoris (chest pain)
  • Treats heart failure
  • Treats arrhythmias or palpitations
  • prevents heart attack and migraine

HOW METOZEST XL 12.5 TABLET WORKS

In hypertension, METOZEST XL 12.5 TABLET works by blocking the effect of adrenaline on the heart and decreasing cardiac output, also reducing the outflow of sympathetic neurons, and suppressing renin activity (normally responsible for the increase in blood pressure). Together, these actions lower blood pressure effectively.

In angina pectoris, METOZEST XL 12.5 TABLET works by blocking adrenaline effects on the heart and decreases the heart rate, blood pressure, and extent of heart contraction. It also reduces the oxygen requirements of the heart, providing relief from angina.

In heart failure, METOZEST XL 12.5 TABLET slows down the heart rate and makes it easier for the heart to pump blood around the body.

DIRECTIONS FOR USE

Take METOZEST XL 12.5 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

SIDE EFFECTS OF METOZEST XL 12.5 TABLET

COMMON

  • feeling faint on standing because of low blood pressure
  • tiredness
  • slow heartbeat
  • difficulty in maintaining balance with fainting,
  • cold hands and feet
  • palpitations
  • dizziness, headache
  • nausea, diarrhoea, constipation, abdominal pain
  • shortness of breath on excessive physical activity

UNCOMMON

  • fluid retention (swelling)
  • worsening of heart failure
  • chest pain
  • pins and needles
  • muscle cramps
  • vomiting
  • weight gain
  • depression, reduced concentration
  • difficulty in sleeping
  • drowsiness
  • nightmare
  • shortness of breath
  • skin rash
  • increased sweating

RARE

  • worsening of diabetes
  • nervousness, anxiety
  • visual disturbances
  • dry or irritated eyes
  • conjunctivitis
  • impotence
  • bending of penis on erection
  • irregular heartbeat
  • heart conduction disturbances
  • dry mouth
  • runny nose
  • hair loss
  • changes in liver function tests

Stop taking METOZEST XL 12.5 TABLET and contact your physician immediately if you experience any of the following side effects:

  • symptoms of an allergic reaction such as skin rash, itching, flushing, swelling of the face, lips, tongue or throat, difficulty in breathing or swallowing

HOW TO MANAGE SIDE EFFECTS

Headache:

Rest and relax. Drink plenty of fluids to keep yourself hydrated. Apply a pain-relieving balm on the head if necessary. Contact your doctor if your headache does not improve.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any machines if you feel dizzy. Do not drink alcohol, as it can aggravate your dizziness. Contact your doctor if your dizziness does not improve.

Nausea, vomiting:

Take the medicine with or just after a meal. Stick to simple meals. Avoid eating oily or spicy foods. Contact your doctor if nausea and vomiting do not improve.

Stomach pain:

Try to rest and relax. Eat small meals but take them frequently. Keep a heating pad on your stomach. Contact your doctor if the stomach pain gets worse.

Diarrhoea:

Drink lots of fluids, such as water or fruit juice, to keep you hydrated. Do not take any medicine on your own to treat diarrhoea. Contact your doctor if your diarrhoea does not improve.

Constipation:

Eat fiber-rich foods such as fresh fruits, vegetables, and cereals. Drink more water and exercise regularly. Contact your doctor if constipation does not improve.

Skin rash:

Avoid hot showers, as they may irritate the skin. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if the rashes get worse.

WARNING & PRECAUTIONS

PREGNANCY

METOZEST XL 12.5 TABLET is not recommended for use in pregnant women unless considered necessary by your doctor. Contact your doctor before taking METOZEST XL 12.5 TABLET.

BREASTFEEDING

METOZEST XL 12.5 TABLET should be used with caution in breastfeeding women as it may pass through breast milk. Contact your doctor before taking METOZEST XL 12.5 TABLET.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel dizzy and tired after taking METOZEST XL 12.5 TABLET.

ALCOHOL

Avoid alcohol consumption while taking METOZEST XL 12.5 TABLET as it lowers your blood pressure.

KIDNEY

METOZEST XL 12.5 TABLET should be used with caution in patients with kidney diseases such as abnormal function. Contact your doctor before taking METOZEST XL 12.5 TABLET.

LIVER

METOZEST XL 12.5 TABLET should be used with caution in patients with liver diseases. Contact your doctor before taking METOZEST XL 12.5 TABLET.

ALLERGY

Do not take METOZEST XL 12.5 TABLET if you are allergic to Metoprolol or any other ingredients in this medicine.

LUNGS

METOZEST XL 12.5 TABLET is not recommended for use in patients with bronchospastic diseases like asthma or COPD. Contact your doctor before taking METOZEST XL 12.5 TABLET.

HEART DISEASE

METOZEST XL 12.5 TABLET is not recommended for use in patients with severe bradycardia, low blood pressure, second or third-degree heart block, cardiogenic shock, decompensated cardiac failure, or sick sinus syndrome (unless a permanent pacemaker is present) and should be used with caution in patients with 1st-degree heart block, myocardial infarction, angina pectoris, heart failure, diseases of the heart valve, or enlarged heart muscle. Contact your doctor before taking METOZEST XL 12.5 TABLET.

OTHERS

METOZEST XL 12.5 TABLET is not recommended for use if you have:

  • severe peripheral arterial disease
  • metabolic acidosis
  • untreated phaeochromocytoma

Before taking METOZEST XL 12.5 TABLET, inform your doctor if you have:

  • major surgery or anaesthesia
  • stroke
  • diabetes or low blood sugar
  • hyperthyroidism
  • history of severe anaphylactic reactions
  • peripheral vascular disease
  • psoriasis

Use in paediatrics:

METOZEST XL 12.5 TABLET is not recommended for use in children less than 6 years of age. Contact your doctor before taking METOZEST XL 12.5 TABLET.

Use in geriatrics:

METOZEST XL 12.5 TABLET should be used with caution in elderly patients aged 65 years or above. Contact your doctor before taking METOZEST XL 12.5 TABLET.

INTERACTIONS

A. Drug-Drug interactions:

Before taking METOZEST XL 12.5 TABLET inform your doctor if you are taking any of the following medicine:

  • reserpine, clonidine, hydralazine, alpha-methyldopa, guanfacine, diltiazem, and verapamil (medicines used for high blood pressure)
  • quinidine, amiodarone, propafenone, disopyramide (medicines used to treat arrhythmias)
  • fluoxetine, paroxetine, sertraline, phenelzine, tranylcypromine (medicines used to treat depression)
  • digitalis (a medicine used to treat heart failure)
  • cimetidine (a medicine used to treat ulcers)
  • terbinafine (a medicine used to treat fungal infection)
  • hydroxychloroquine (a medicine used to treat malaria)
  • medicines used to treat psychoses (Ex. chlorpromazine, triflupromazine, chlorprothixene)
  • diphenhydramine (medicines used to treat allergies)
  • celecoxib, indomethacin (medicines used to treat pain)
  • rifampicin (medicines used to treat tuberculosis)
  • other beta-blockers, Ex.  timolol eye drops
  • adrenaline, noradrenaline (medicines used to treat shock)
  • medicines used for diabetes mellitus Ex. glimepiride
  • lidocaine (a medicine used to induce numbness)

Overdosage:

If you or anyone else has accidentally taken too much of METOZEST XL 12.5 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are nausea, vomiting, bluish discolouration of the skin, severe bradycardia, low blood pressure (fatigue, dizziness), atrioventricular block, heart failure, bronchospasm or shortness of breath, hypoxia, cardiac arrest, cardiogenic shock, impairment of consciousness or coma.

SYNOPSIS

Drug :  

Metoprolol

Pharmacological Category :  

Beta-blockers

Therapeutic Indication :  

High blood pressure, Angina pectoris, Heart failure

Dosage Forms :  

Tablet, Capsule, Injection

MORE INFORMATION

  • Keep METOZEST XL 12.5 TABLET out of the sight and reach from children
  • Store METOZEST XL 12.5 TABLET at room temperature

FAQs ABOUT METOZEST XL 12.5 TABLET

How METOZEST XL 12.5 TABLET work?

In hypertension, METOZEST XL 12.5 TABLET works by blocking the effect of adrenaline on the heart and decreasing cardiac output, also reducing the outflow of sympathetic neurons and suppressing renin activity (normally responsible for an increase in blood pressure). Together, these actions lower blood pressure effectively.

In angina pectoris, METOZEST XL 12.5 TABLET works by blocking adrenaline effects on the heart and decreases the heart rate, blood pressure, and extent of heart contraction. It also reduces the oxygen requirements of the heart, providing relief from angina.

In heart failure, METOZEST XL 12.5 TABLET slows down the heart rate and makes it easier for the heart to pump blood around the body.

What is METOZEST XL 12.5 TABLET used for?

METOZEST XL 12.5 TABLET contains Metoprolol, which belongs to the group of medicines called Beta-blockers. It is used to treat high blood pressure, angina pectoris (chest pain), and heart failure. It is also used to treat arrhythmias or palpitations and to prevent heart attacks and migraines. Contact your doctor before taking METOZEST XL 12.5 TABLET.

Can METOZEST XL 12.5 TABLET be used for treating asthma?

METOZEST XL 12.5 TABLET is not recommended for use in patients with bronchospastic diseases like asthma or COPD. Contact your doctor before taking it.

Can METOZEST XL 12.5 TABLET cause high blood sugar?

Yes. METOZEST XL 12.5 TABLET may raise blood sugar levels and should be used with caution in patients with diabetes or low blood sugar. Contact your doctor before taking METOZEST XL 12.5 TABLET.

Can METOZEST XL 12.5 TABLET cause low blood pressure?

Yes. METOZEST XL 12.5 TABLET can cause low blood pressure and causes dizziness, headache, sweating, and faintness on standing up. Contact your doctor before taking METOZEST XL 12.5 TABLET.

Can I stop taking METOZEST XL 12.5 TABLET if I feel better?

Do not stop METOZEST XL 12.5 TABLET suddenly without informing your physician. As it may lead to an exacerbation of angina pectoris (chest pain) or myocardial infarction (heart attack). Contact your doctor before stop taking it.

REFERENCES

1. K D Tripathi. Cardiovascular drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page - 523, 545, 564.

2. Bethesda (MD). Metoprolol. National Institute of Health. NLM. National Centre for Biotechnology Information. PubMed, 2006. [Accessed on 30th June 2022] https://www.ncbi.nlm.nih.gov/books/NBK501156/

3. Jason Morris, Alexis Dunham. Metoprolol. National Institute of Health. NLM. National Centre for Biotechnology Information. Pubmed.gov, January 2022. [Accessed on 30th June 2022] https://www.ncbi.nlm.nih.gov/books/NBK532923/

4. Aralez Pharmaceuticals US Inc. Metoprolol. [Revised in December 2016] [Accessed on 30th June 2022] https://www.toprol-xlhcp.com/assets/Toprol-PI-Clean.pdf

5. Dr Reddy’s Laboratories Limited. Metoprolol. [Revised in April 2016] [Accessed on 30th June 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4d382c97-704d-1603-e054-00144ff8d46c

6. STADA Arzneimittel AG. Metoprolol. [Accessed on 30th June 2022] https://file.wuxuwang.com/hma/DK_H_1308_001_FinalPL.pdf

USEFUL DIAGNOSTIC TESTS

  • Kidney function test

PRODUCT DETAILS

    Country Of Origin
    India
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ALTERNATE BRANDS
METOLET XL 12.5 Tablet 10's
Prescription Hypertension Rx required
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METOZEST XL 12.5 Tablet 10's

METOZEST XL 12.5 Tablet 10's Mkt: Innovative Pharmaceuticals Pvt Ltd

M.R.P.: Rs.36.50
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