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INTRODUCTION
METOSAFE XL 25MG contain Metoprolol Succinate which belongs to a group of medicine called beta-blockers. It is used to treat high blood pressure, irregular heartbeat and prevent heart attack and strokes, angina pectoris, migraine. High blood pressure is a condition in which the force of the blood against the artery wall. Improper beating of the heart, whether irregular, too fast, or too slow. This is also called as irregular heartbeat or arrhythmia.
Heart attack occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle. This is also called as myocardial infarction. Stroke occurs when a blood vessel that carries oxygen and nutrients to the brain is either blocked by a clot or bursts (or ruptures). Angina pectoris is a type of chest pain caused by reduced blood flow to the heart. Migraine is a neurological condition that can cause multiple symptoms. It is frequently characterized by intense, debilitating headache.
Always take METOSAFE XL 25MG exactly as your doctor has told you. This medicine must be taken with or without food. It is not recommended for use in children and adolescents under 18 years. It can be taken by adults over the age of 18 years. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.
USES OF METOSAFE XL 25MG
- Treat high blood pressure, irregular heartbeat
- Prevent heart attack and strokes, angina pectoris, migraine
HOW METOSAFE XL 25MG WORKS
METOSAFE XL 25MG works by changing the way your body responds to some nerve impulses, especially in the heart. It slows down your heart rate and makes it easier for your heart to pump blood around your body.
DIRECTIONS FOR USE
Always take METOSAFE XL 25MG exactly as your doctor has told you. This medicine must be taken with or without food. Try to take this medicine at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine.
SIDE EFFECTS OF METOSAFE XL 25MG
SERIOUS
- lung problems (symptoms such as shortness of breath, wheezing, and tightening of the chest)
- heart problems (symptoms such as shortness of breath with a cough that gets worse when you exercise (like walking upstairs), swollen ankles or legs, chest pain, an irregular heartbeat)
- thyrotoxicosis (symptoms such as fast heart rate, high temperature (38°C and above), trembling and confusion)
- liver problems (symptoms such as yellow skin or the whites of your eyes turn yellow)
- serious allergic reaction (such as anaphylaxis, skin rash that may include itchy, red, swollen, blistered or peeling skin, tightness of the throat, trouble breathing or talking, swelling of mouth, face, lips, tongue, or throat)
COMMON
- headache
- feeling tired, dizziness or weak
- cold hands or feet
- nausea
- stomach ache
HOW TO MANAGE SIDE EFFECTS
Headache:
Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.
Dizziness:
Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.
Nausea:
Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
Stomach ache:
Try to rest and relax. Eat and drink slowly or have smaller and frequent meals. Applying heat pad or covered hot water bottle on your stomach may also help. If still pain persists, speak to your doctor.
WARNING & PRECAUTIONS
PREGNANCY
METOSAFE XL 25MG should be used with caution in pregnant women. Consult your doctor before taking this medicine.
BREASTFEEDING
METOSAFE XL 25MG should be used with caution in breast feeding women. Consult your doctor before taking this medicine.
DRIVING AND USING MACHINES
Do not drive or operate any machine while taking this medicine it may cause dizziness.
ALCOHOL
Consumption of alcohol is not recommended during treatment with METOSAFE XL 25MG.
KIDNEY
METOSAFE XL 25MG should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.
LIVER
METOSAFE XL 25MG should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.
ALLERGY
Do not take METOSAFE XL 25MG if you are allergic (hypersensitive) to Metoprolol Succinate or any other ingredients in this medicine.
LUNGS
METOSAFE XL 25MG should be used with caution in patients suffering from active lung diseases(asthma). Consult your doctor for advice.
HEART DISEASE
METOSAFE XL 25MG should be used with caution in patients suffering from active heart diseases. Consult your doctor for advice.
OTHERS
Tell your doctor if you have or had a condition such as,
- low blood pressure
- metabolic acidosis
- overactive thyroid (hyperthyroidism) or thyrotoxicosis
- severe blood circulation problems in your limbs (such as Raynaud's phenomenon) which may make your fingers and toes tingle or turn pale or blue
- low blood sugar
INTERACTIONS
Talk to your doctor if you are taking,
- medicines for high blood pressure
- antidepressants (used to treat depression)
- nitrates (used to treat chest pain)
- baclofen (used for muscle relaxant)
- tamsulosin (used for an enlarged prostate)
- co-careldopa and levodopa (used to treat parkinson's disease)
- non-steroidal anti-inflammatory medicines (NSAIDs) such as ibuprofen
- pseudoephedrine or xylometazoline (used to treat cough)
- medicines for diabetes
- ephedrine, noradrenaline, or adrenaline (used to treat allergy)
- medicines for asthma or chronic obstructive pulmonary disease (COPD)
SYNOPSIS
| Drug | : | Metoprolol Succinate |
| Pharmacological Category | : | Beta-blockers |
| Therapeutic Indication | : | High blood pressure, irregular heartbeat, heart attack and strokes, angina pectoris, migraine |
| Dosage Forms | : | Tablet, Capsule, Injection |
MORE INFORMATION
Store below 20-25°C and keep out of reach of children.
FAQs ABOUT METOSAFE XL 25MG
Can METOSAFE XL 25MG be used in children?
No, this medicine is strictly not recommended for use in children and adolescents under 18 years.
Can I take METOSAFE XL 25MG during alcohol?
No, this medicine is strictly not recommended during alcohol consumption.
Can METOSAFE XL 25MG cause dizziness?
Yes, this medicine may cause dizziness in some individuals. Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.
REFERENCES
1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page-2539-2543.
2. Jason Morris; Alexis Dunham. Metoprolol. US National Library of Medicines, National Institutes of Health. 10 Jul 2020. [Accessed 23 Nov 2020] https://www.ncbi.nlm.nih.gov/books/NBK532923/
3. Dragos Vinereanu 1, Jindrich Spinar 2 3, Atul Pathak 4, Dariusz Kozlowski 5. Role of Metoprolol Succinate in the Treatment of Heart Failure and Atrial Fibrillation: A Systematic Review. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. Mar/ Apr 2020. [Accessed 23 Nov 2020] https://pubmed.ncbi.nlm.nih.gov/31385823/
4. National Health Service (NHS); Electronic Medicines Compendium (EMC); [Revised on 13 Dec 2018] [Accessed 23 Nov 2020] https://www.nhs.uk/medicines/metoprolol/
USEFUL DIAGNOSTIC TESTS
- Kidney function test
Manufacturer/Marketer Details
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