METHYLPREDNI 4 Tablet 10's

Hormonal Therapy Rx required

Best Price* ₹ 40.00 MRP ₹ 50.00
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: R T PHARMA * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

METHYLPREDNI 4 TABLET contains Methylprednisolone which belongs to the group of medicines called Corticosteroids. It is used to treat problematic conditions of the adrenal glands (such as adrenal insufficiency, congenital adrenal hyperplasia and nonsuppurative thyroiditis).

It can also be used to treat various inflammatory auto-immune disease conditions affecting the bones and joints (Ex. rheumatoid arthritis, ankylosing spondylitis), skin and collagen (Ex. systemic lupus erythematosus, psoriasis), eyes (Ex. optic neuritis, uveitis or iritis), respiratory tract (Ex. asthma, tuberculosis), blood or blood vessels (Ex. leukaemia), bowel and gut (Ex. Crohn’s disease and ulcerative colitis) and brain (Ex. tuberculous meningitis).

It is also indicated in the treatment of drug induced hypersensitivity reactions and in other allergic reactions (such as atopic dermatitis, allergic conjunctivitis and allergic rhinitis). It also helps in prevention of graft rejection following organ transplantation and increases urine output or reduces protein loss in urine among patients having kidney problems (such as nephrotic syndrome).

Take METHYLPREDNI 4 TABLET as advised by your physician. Do not stop taking METHYLPREDNI 4 TABLET or reduce the dose of methylprednisolone without consulting your doctor as it may lead to unpleasant withdrawal symptoms, especially if you are taking higher dose of methylprednisolone.

Before taking METHYLPREDNI 4 TABLET inform your doctor if you any viral infections, or any liver, kidney or heart problems. You must also inform your doctor if you have hypertension, diabetes, thyroid deficiency, glaucoma, skin problem, gut inflammation, muscle problems, osteoporosis, any types of tumors or cancer in the body, depression or any other forms of mental illness.

METHYLPREDNI 4 TABLET should be used in pregnant or breastfeeding women only if it is considered necessary by the physician. Avoid drinking grapefruit juice or eating grapefruit while taking METHYLPREDNI 4 TABLET as it may lead to unwanted side effects.

The most common side effects of taking METHYLPREDNI 4 TABLET are high blood pressure, swelling of body parts, muscle cramps or weakness, skin thinning, feeling sad or depressed and slowed growth in children. Consult your doctor if any of these side effect worsens.

You must also inform your doctor if you experience severe depression with suicidal thoughts or severe stomach pain with blood-stained stools or vomit.

USES OF METHYLPREDNI 4 TABLET

It is used to treat the following disease conditions:

  • adrenal insufficiency and its associated conditions
  • bone and joint problems (Ex. rheumatoid arthritis, ankylosing spondylitis)
  • skin and collagen disorders (Ex. systemic lupus erythematosus, psoriasis)
  • eye problems (Ex. optic neuritis, uveitis or iritis)
  • respiratory tract diseases (Ex. asthma, tuberculosis)
  • blood cancer (leukemia), lymph cancer (lymphoma)
  • problems of bowel and gut (Ex. Crohn’s disease and ulcerative colitis)
  • brain problems (Ex. tuberculous meningitis)
  • drug induced hypersensitivity reactions
  • allergic reactions (such as atopic dermatitis, allergic conjunctivitis and allergic rhinitis)

It can also:

  • prevent graft rejection following organ transplantation
  • improve urine output or reduces protein loss in urine among patients having nephrotic syndrome

HOW METHYLPREDNI 4 TABLET WORKS

METHYLPREDNI 4 TABLET is a corticosteroid medicine with anti-inflammatory and immune suppressant properties. It boosts your body with sufficient corticosteroid levels (cortisol, aldosterone) during deficient conditions and helps your body to function properly.

It also reduces the release of certain chemicals (prostaglandins) in the body that causes inflammation. It prevents graft rejection by suppressing the immune functions and protects your kidney from damage in patients with kidney problems.

DIRECTIONS FOR USE

Take METHYLPREDNI 4 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking METHYLPREDNI 4 TABLET without consulting your doctor.

SIDE EFFECTS OF METHYLPREDNI 4 TABLET

COMMON

  • high blood pressure (causing headache, or a general feeling of being unwell)
  • swelling of body parts
  • muscle cramps, weakness or wasting
  • cataract, blurred vision
  • slowed growth in children
  • moon shaped face (Cushingoid facies)
  • feeling sad, mood changes, mania, anxiety
  • problems in sleeping
  • difficulty in thinking, confusion, loss of memory, hallucinations
  • fear or frightening thoughts
  • acne, poor wound healing
  • skin thinning

RARE

Contact your doctor immediately if you experience any of the following side effects while undergoing therapy with METHYLPREDNI 4 TABLET:

  • signs of allergic reaction (such as skin rash, itching, blistering and peeling of the skin, swelling of the face, lips, mouth, throat which may lead to breathing difficulties)
  • signs of bleeding in the gut (such as stomach pain which radiates until your back, bleeding from the anus, black or blood-stained stools, blood in vomit)
  • increased infections causing fever or a general feeling of being unwell
  • signs of flare up of a previous tuberculosis infection (such as coughing blood or pain in the chest)
  • signs of pancreatitis (inflammation of pancreas causing severe stomach pain and vomiting)
  • signs of blood clot in lungs (such as sharp chest pain, shortness of breath, coughing up blood)
  • signs of increased pressure within the skull (such as severe headaches with vomiting, lack of energy and drowsiness) usually occurs once therapy is stopped
  • thrombophlebitis (blood clots in vein supplying the legs causing leg pain, swelling, redness and tenderness)
  • feeling depressed, suicidal thoughts
  • blurred vision or other visual disturbances

HOW TO MANAGE SIDE EFFECTS

Headache:  

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

WARNING & PRECAUTIONS

PREGNANCY

METHYLPREDNI 4 TABLET should be used in pregnant women only if it is considered necessary by the physician. Therefore, inform your doctor before taking METHYLPREDNI 4 TABLET if you are pregnant, think you may be pregnant or planning to have a baby.

BREASTFEEDING

METHYLPREDNI 4 TABLET should be used in breastfeeding women only if it is considered necessary by the physician. Therefore, inform your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or operate any heavy tools or machines if you experience dizziness after taking METHYLPREDNI 4 TABLET.

ALCOHOL

Avoid consumption of alcohol while taking METHYLPREDNI 4 TABLET as it may make you feel drowsier.

KIDNEY

METHYLPREDNI 4 TABLET should be used with caution in patients with kidney diseases. Therefore, consult your doctor before taking it.

LIVER

METHYLPREDNI 4 TABLET should be used with caution in patients with liver diseases. Therefore, consult your doctor before taking it.

ALLERGY

Do not take METHYLPREDNI 4 TABLET if you are allergic to Methylprednisolone.

LUNGS

METHYLPREDNI 4 TABLET is not recommended for use in patients with fungal infection of the lungs. Therefore, consult your doctor before taking it.

HEART DISEASE

METHYLPREDNI 4 TABLET should be used with caution in patients with heart problems (such as recent heart attack or heart failure). Therefore, consult your doctor before taking it.

OTHERS

METHYLPREDNI 4 TABLET is not recommended for use if you:

  • have serious untreated fungal infections (Ex. infection of lungs or esophagus)
  • got vaccinated recently or scheduled for any upcoming vaccinations

Before taking METHYLPREDNI 4 TABLET, inform your doctor if you:

  • have or had been in contact with someone who has chickenpox, measles or shingles
  • have or ever had severe depression or bipolar disorder
  • have a family history of mental illness
  • have diabetes or a family history of diabetes
  • have fits
  • have or have a family history of glaucoma
  • have viral or fungal infections of the eyes
  • have hypertension (high blood pressure)
  • have underactive thyroid gland (hypothyroidism)
  • have inflammation of pancreas or gut lining (peritonium)
  • have scleroderma (an autoimmune disorder causing skin tightness, cold extremities, joint pain and heart burn)
  • have Kaposi’s sarcoma (a type of skin cancer)
  • have any muscle problems (Ex. myasthenia gravis)
  • have osteoporosis (brittle bones)
  • have pheochromocytoma (a rare tumor of the adrenal glands)
  • have skin abscess
  • have stomach ulcer or other serious stomach or intestinal problems
  • have thrombophlebitis (clots in veins)
  • have or had tuberculosis
  • have Cushing’s disease
  • have brain injury due to trauma
  • have any unusual stress
  • are scheduled for any upcoming surgery (including dental surgery)

Use in pediatrics:

METHYLPREDNI 4 TABLET should be used in children and adolescents (aged below 18 years) only if prescribed by the physician. Therefore, consult your doctor for advice before taking it.

Use in geriatrics:

METHYLPREDNI 4 TABLET should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before taking it.

INTERACTIONS

A. Drug-Drug interactions:

Before taking METHYLPREDNI 4 TABLET, inform your doctor if you are taking any of the following medicines such as:

  • acetazolamide (a medicine used to treat glaucoma or edema)
  • aminoglutethimide or cyclophosphamide (used for treating cancer)
  • anticoagulants (used for blood thinning) such as acenocoumarol, phenindione and warfarin
  • anti-cholinergic medicines used to treat myasthenia gravis (such as distigmine and neostigmine)
  • medicines used to treat bacterial infections (Ex. isoniazid, erythromycin, clarithromycin and troleandomycin)
  • medicines used to treat diabetes (Ex. metformin, glipizide)
  • aprepitant or fosaprepitant (used to prevent nausea and vomiting)
  • non-steroidal anti-inflammatory medicines (used for fever and pain relief) such as aspirin, ibuprofen
  • medicines used to treat epilepsy (such as carbamazepine, phenytoin and primidone)
  • carbenoxolone and cimetidine (used to treat stomach ulcer and acid reflux)
  • ciclosporin, tacrolimus (medicines used to suppress immune function and to prevent graft rejection)
  • medicines used to treat chest pain, hypertension or irregular heartbeat (such as digoxin, diltiazem or mibefradil)
  • oral contraceptives (birth control pills) Ex. ethinylestridiol and norethisterone
  • medicines used to treat HIV infection (such as ritonavir, indinavir, cobicistat)
  • medicines used to treat fungal infection (such as ketoconazole, amphotericin B, itraconazole)
  • muscle relaxants (Ex. pancuronium or vecuronium)
  • diuretics (used to treat edema and hypertension) Ex. furosemide, chlorothiazide, hydrochlorothiazide
  • medicines used to treat asthma (such as aminophylline, salmeterol, formoterol)
  • rifampicin and rifabutin (used to treat tuberculosis)
  • live vaccines

B. Drug-Food interaction:

Avoid drinking grapefruit juice or eating grapefruit while taking METHYLPREDNI 4 TABLET as it may lead to unwanted side effects.

Overdosage:

If you or anyone else accidentally took more METHYLPREDNI 4 TABLET, consult your doctor immediately or visit the nearby hospital straight away.

SYNOPSIS

Drug :  

Methylprednisolone

Pharmacological Category :  

Synthetic Glucocorticoids

Therapeutic Indication :  

Adrenal insufficiency, Auto Immune Disease, Allergic reactions, Prevent graft rejection, Proteinuria

Dosage Forms :  

Tablet, Injection, Cream

MORE INFORMATION

  • Keep METHYLPREDNI 4 TABLET out of reach of children
  • Store METHYLPREDNI 4 TABLET at room temperature

FAQs ABOUT METHYLPREDNI 4 TABLET

What is METHYLPREDNI 4 TABLET used for?

METHYLPREDNI 4 TABLET is a corticosteroid medicine used to treat adrenal insufficiency. It can also be used to treat drug induced hypersensitivity reactions, allergic reactions and various inflammatory auto-immune disease conditions affecting the skin, collagen, bones and joints, brain, gut, eyes etc. It also helps in prevention of graft rejection following organ transplantation and increases urine output among patients having kidney problems.

How to take METHYLPREDNI 4 TABLET?

Swallow METHYLPREDNI 4 TABLET with a glass of water. Do not crush or chew the medicine.

Is METHYLPREDNI 4 TABLET a steroid?

Yes. METHYLPREDNI 4 TABLET is synthetic corticosteroid used to treat problems of adrenal gland and various allergic, hypersensitivity and inflammatory autoimmune disease conditions.

What are the most common side effects of METHYLPREDNI 4 TABLET?

The most common side effects of taking METHYLPREDNI 4 TABLET are high blood pressure, swelling of body parts, muscle cramps or weakness, skin thinning, feeling sad or depressed and slowed growth in children. Consult your doctor if any of these side effect worsens.

Can METHYLPREDNI 4 TABLET make you feel high?

Yes. METHYLPREDNI 4 TABLET may make you feel high. Such symptoms may disappear once the therapy has been stopped. However, consult your doctor if it bothers you.

How does METHYLPREDNI 4 TABLET works?

METHYLPREDNI 4 TABLET boosts your body with sufficient corticosteroid levels and helps your body to function properly. It also reduces the release of certain chemicals in the body that causes inflammation. It also prevents graft rejection by suppressing the immune functions and protects your kidney from damage in patients with kidney problems.

How long will it take for METHYLPREDNI 4 TABLET to control my disease?

The time taken by METHYLPREDNI 4 TABLET to control the disease may vary from person-to-person depending upon the dose of methylprednisolone administered and disease severity.

Is METHYLPREDNI 4 TABLET safe to use in diabetic patients?

METHYLPREDNI 4 TABLET may alter the blood sugar levels in your body. Therefore, it is necessary to inform your doctor if you have diabetes before taking METHYLPREDNI 4 TABLET as a precaution.

Who should not take METHYLPREDNI 4 TABLET?

METHYLPREDNI 4 TABLET is not recommended for use in patients with serious fungal infections. It is also not suitable for use in patients who got vaccinated recently.

Can I take a higher dose of METHYLPREDNI 4 TABLET?

No. It is not safe to take a higher dose of METHYLPREDNI 4 TABLET without consulting your doctor. If the prescribed dose is less effective for you, kindly consult your doctor for a suitable high dose or for an alternative therapy.

Can I take METHYLPREDNI 4 TABLET daily?

Your doctor will evaluate your health condition and suggests whether can you take METHYLPREDNI 4 TABLET every day or not.

Can I stop taking METHYLPREDNI 4 TABLET once by pain reduces?

Take METHYLPREDNI 4 TABLET for the stipulated duration recommended by your doctor to achieve maximum results. Do not stop taking METHYLPREDNI 4 TABLET or reduce the dose of methylprednisolone without consulting your doctor, as sudden cessation of the therapy may lead to unpleasant withdrawal symptoms such as skin itchiness, fever, headache, muscle pain, joint pain, runny nose, tiredness or weight loss, especially if you are taking higher dose of methylprednisolone.

Can METHYLPREDNI 4 TABLET be used in children?

METHYLPREDNI 4 TABLET should be used in children and adolescents (aged below 18 years) only if prescribed by the physician. Therefore, consult your doctor for advice before taking it.

What to do if I forgot to take a dose of METHYLPREDNI 4 TABLET?

If you forgot to take a dose of METHYLPREDNI 4 TABLET, take it as soon as you remember. However, if it is time for the next dose of METHYLPREDNI 4 TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of METHYLPREDNI 4 TABLET to compensate the missed ones.

Will METHYLPREDNI 4 TABLET alter the effects of birth control pills?

METHYLPREDNI 4 TABLET may reduce the effects of birth control pills. Therefore, try to avoid taking birth control pills along with METHYLPREDNI 4 TABLET. Consult your doctor for advice.

Can METHYLPREDNI 4 TABLET be used in pregnant women?

METHYLPREDNI 4 TABLET should be used in pregnant women only if it is considered necessary by the physician. Therefore, inform your doctor before taking METHYLPREDNI 4 TABLET if you are pregnant, think you may be pregnant or planning to have a baby.

REFERENCES

1. KD. Tripathi. Corticosteroids. Essentials of medical pharmacology. Eighth Edition. 2019. Page – 313.

2. Antonio Ocejo, Ricardo Correa. Methylprednisolone. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. [Revised in December 2021]. [Accessed on 8th October 2022] https://www.ncbi.nlm.nih.gov/books/NBK544340/

3. Jicheng Lv, MD, Hong Zhang, PhD, Muh Geot Wong, PhD. Effect of Oral Methylprednisolone on Clinical Outcomes in Patients with IgA Nephropathy: The TESTING Randomized Clinical Trial. JAMA Network. August 2017. [Accessed on 8th October 2022] https://jamanetwork.com/journals/jama/fullarticle/2646717

4. Pfizer Italia S.r.l. Electronic Medicines Compendium (EMC). [Revised in November 2018] [Accessed on 8th October 2022] https://www.medicines.org.uk/emc/files/pil.1085.pdf

5. Pfizer Italia S.r.l. Electronic Medicines Compendium (EMC). [Revised in November 2018] [Accessed on 8th October 2022] https://www.medicines.org.uk/emc/files/pil.1086.pdf

6. Methylprednisolone. Pfizer. [Revised in February 2019] [Accessed on 8th October 2022] https://labeling.pfizer.com/showlabeling.aspx?id=601

7. Central Drugs Standard Control Organization. Methylprednisolone Tablet 8mg. [Revised in September 2009]. [Accessed on 8th October 2022] https://cdscoonline.gov.in/CDSCO/Drugs

8. Predniwel 8. Leeford Healthcare Ltd. [Accessed on 8th October 2022] https://www.leeford.in/product/1072/predniwel-8

USEFUL DIAGNOSTIC TESTS

  • Absolute Eosinophil Count
  • Anti-Nuclear Antibody
  • Anti-ds-DNA Antibody
  • Anti-ds-DNA Antibody-IFA
  • Peripheral Smear Examination
  • Total IgE

PRODUCT DETAILS

    Country Of Origin
    India
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METHYLPREDNI 4 Tablet 10's

METHYLPREDNI 4 Tablet 10's Mkt: R T PHARMA

M.R.P.: Rs.50.00
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